Results 121 to 130 of about 36,498 (214)

Kinetic and structural characterisation of domain‐specific angiotensin I‐converting enzyme inhibition by captopril, rentiapril and zofenoprilat

The FEBS Journal, Volume 293, Issue 11, Page 3399-3414, June 2026.
Angiotensin I‐converting enzyme (ACE) contains two catalytic domains (nACE and cACE) and is a key therapeutic target for hypertension and cardiovascular disease. Current ACE inhibitors (ACEi) nonselectively inhibit both domains, causing adverse effects. Selective inhibition requires an understanding of domain‐specific binding.
Kyle S. Gregory, Vinasha Ramasamy, Edward D. Sturrock, K. Ravi Acharya   +3 more
wiley   +1 more source

Modest Contribution of Bradykinin to Blood Pressure Reduction by Sacubitril/Valsartan in Chronic Heart Failure. [PDF]

Circ Heart Fail
Gupta DK, Stevenson LW, Garner EM, Maulion C, Nian H, Wright PR, Turcu AF, Wei S, Brown NJ.   +8 more
europepmc   +1 more source

Loss of Striatal Bradykinin B2 Receptor Alters Anxiety and Motivational Behaviors in Male Mice

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
Impaired signaling of the bradykinin B2 receptor (B2R) in dorsal striatal neurons decreases anxiety‐like behavior and sucrose preference while enhancing voluntary running in mice. These results reveal a novel role for B2R in dopaminergic circuits that modulate motivation and emotional behavior.
Mariana Rosolen Tavares, Ronaldo Carvalho Araujo, Marina Galleazzo Martins, Jose Donato Jr, Michael Bader, Frederick Wasinski   +5 more
wiley   +1 more source

Acquired Angioedema-A Challenge in Medical Practice: A Narrative Review. [PDF]

J Clin Med
Poznańska-Kurowska K, Skibińska M, Lorenz D, Aman Ur Rahman W, Kurowski M.   +4 more
europepmc   +1 more source

ACE inhibitor-induced bradykinin-mediated angioedema presenting as small bowel obstruction and life-threatening airway angioedema: a rare dual presentation. [PDF]

BMJ Case Rep
Ghimire P, Sathya DA, Tang A, Yaqoob H.
europepmc   +1 more source

Glycocalyx strengthens endothelial barrier function and protects from angioedema inducing compounds. [PDF]

Front Immunol
Reich A, Lehnert E, Möhrle R, Gierke A, Brunner C, Hoffmann TK, Greve J, Hahn J, Lochbaum R.   +8 more
europepmc   +1 more source

Case Report: Hereditary Angioedema Accompanied by Chronic Spontaneous Urticaria. [PDF]

Clin Cosmet Investig Dermatol
Wang H, Shen Y.
europepmc   +1 more source

Bradykinin [PDF]

, 2019
openaire   +1 more source

The immunomodulatory potential of bradykinin signaling in autoimmune conditions. [PDF]

Front Immunol
Szaryńska M, Olejniczak-Kęder A.
europepmc   +1 more source

Lisinopril-Induced Angioedema Triggered by Tattoo Cellulitis and Acute Kidney Injury: A Case Report. [PDF]

Cureus
Zedan M, Howard S, Foryt P, Aroriode T.
europepmc   +1 more source