Results 111 to 120 of about 36,498 (214)

Neurocognitive Aging Following Acute Illness: Pathobiology and a Framework for Developing Neurotherapeutic Agents

open access: yesBrain and Behavior, Volume 16, Issue 6, June 2026.
In this review, we discuss the scientific basis for how neurocognitive aging occurs after critical illness, including sepsis, trauma, and burns, and the clinical need to develop therapies to reduce inflammation, protect the blood–brain barrier, remove senescent cells, and enhance neuroplasticity.
Errin Lawrence   +14 more
wiley   +1 more source

The Silent Link: Exploring the Impact of Periodontal Diseases on Head and Neck Carcinogenesis

open access: yesClinical and Experimental Dental Research, Volume 12, Issue 3, June 2026.
ABSTRACT Objectives Oral dysbiosis can accelerate the progression of head and neck squamous cell carcinoma (HNSCC) by fostering a pro‐inflammatory, immunosuppressive, and metabolically altered environment. This narrative review examines the relationships between periodontitis‐associated bacteria and HNSCC, focusing on their impact on oncogenic pathways,
Yashmin Afshar, Nima Rezaei
wiley   +1 more source

Buck Wheat: Nutritional, Bioactive Characteristics, Health Benefits, and Side Effects

open access: yesFuture Postharvest and Food, Volume 3, Issue 2, Page 142-162, June 2026.
ABSTRACT Micronutrient deficits have resulted from an over‐reliance on a small number of cereal crops for food security. The agricultural sector faces severe sustainability issues due to the rapid growth of the world's population and sudden climatic changes.
Momina Farooq   +2 more
wiley   +1 more source

Unraveling Inflammatory Pain: A Narrative Review of Molecular Pathways and Multidisciplinary Treatments

open access: yesHealth Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background Inflammatory pain is a widespread global health concern arising from complex molecular pathways triggered by a consequence of tissue damage and immune activation. It significantly impacts quality of life and functional outcomes, necessitating a comprehensive understanding of underlying mechanisms and multidisciplinary approaches for
Fatma Mohamed Elmansy   +6 more
wiley   +1 more source

Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends

open access: yesMed Research, Volume 2, Issue 2, Page 309-342, June 2026.
The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
wiley   +1 more source

Investigating the Phytochemical Constituents, Anti‐Inflammatory, and Neuropharmacological Activities of Podocarpus neriifolius Leaves Through FT‐IR, GC–MS, Experimental Studies, Molecular Docking, and Molecular Dynamics Simulations

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Podocarpus neriifolius, a widely distributed medicinal plant in South and Southeast Asia, has traditionally been used to treat rheumatism and joint pain. This study aimed to investigate the phytochemical profile and therapeutic potential of the ethanolic leaf extract of P.
Neamul Hoque   +9 more
wiley   +1 more source

Ca2+‐Activated Cl− Channels: Do Bestrophins and TMEM16A Interact?

open access: yesActa Physiologica, Volume 242, Issue 6, June 2026.
ABSTRACT Aim Ca2+‐activated Cl– conductances are present in many cell types and are important for regulating membrane potential as well as other cellular functions. TMEM16A is widely accepted as the principal molecular basis for Ca2+‐activated Cl– conductances, but also members of the bestrophin family may be important for some Ca2+‐activated Cl ...
Christian Aalkjær   +4 more
wiley   +1 more source

Evaluation of Antioxidant Activity of Methanolic Extracts and some Fractions of Salvia verticillata L. Using Three Different Methods

open access: yesJournal of Medicinal Plants, 2007
Background: Bradykinin has effects on histaminic response,vessels seepage,cellular reproduction,causing fever, pain and coughs caused by ACE controllers (3,4,6).
E Souri   +3 more
doaj  

GRKs and arrestins: Nomenclature and functions in GPCR‐dependent and ‐independent signalling

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 11, Page 2619-2633, June 2026.
G protein‐coupled receptor (GPCR) kinases (GRKs) and arrestins play a critical role in the regulation of GPCR signalling. Historic names of mammalian GRKs were replaced by systematic ones in the 1990s; however, both kinds of names are currently in use for mammalian arrestins.
Vsevolod V. Gurevich
wiley   +1 more source

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