Results 181 to 190 of about 174,356 (352)

Exploration of Therapeutic Targets Using CDK4 Inhibitors for Head and Neck Mucosal Melanoma

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Mucosal melanoma (MM) is an extremely aggressive malignant tumor in the head and neck region associated with a poor prognosis. In the present study, we conducted cell proliferation assay and western blotting using cell lines derived from MM and the immunohistochemical analysis of pathological MM tissues to identify novel therapeutic ...
Takayoshi Hattori, Makiko Fujii, Tsutomu Ueda, Akira Ishikawa, Yuichi Mine, Bingwen Xu, Tomoya Suehiro, Minoru Hattori, Hiroaki Tahara, Yuki Sato, Nobuyuki Chikuie, Takayuki Taruya, Takao Hamamoto, Takashi Ishino, Sachio Takeno   +14 more
wiley   +1 more source

Influence of the tumor microenvironment on genetic mutations in thyroid carcinoma. [PDF]

PLoS One
Zhou L, Xu S, Song Y, Jiang D, Chen S.
europepmc   +1 more source

The BRAF and NRAS mutation prevalence in dermoscopic subtypes of acquired naevi reveals constitutive mitogen‐activated protein kinase pathway activation [PDF]

, 2018
J.M. Tan, Loosli Tom, K. Jagirdar, D. Lambie, H. Schaider, R.A. Sturm, H. Peter Soyer, Mitchell Stark   +7 more
openalex   +1 more source

Integrating artificial intelligence (AI) into colorectal cancer reporting

The Journal of Pathology, EarlyView.
Abstract Artificial intelligence (AI) and deep learning (DL) are transforming cancer research and clinical care, with histopathology playing a central role in this transformation. In colorectal cancer (CRC), the second leading cause of cancer mortality world‐wide, multimodal and vision‐language models (VLMs) hold particular promise for enhancing the ...
Konstantin Bräutigam, Ann‐Marie Baker, Viktor H Koelzer, Jakob N Kather, Trevor A Graham   +4 more
wiley   +1 more source

Concordance and Discordance Rates of V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF) ^V600E Status in Metastatic against Primary Lesion of Melanoma: A Meta-analysis

, 2020
Hiroshi Yokomichi, Takashi Inozume, Makoto Wada, Jun Asai, Hiroshi Igaki, Kenjiro Namikawa, Ayato Hayashi, Satoshi Fukushima, Taku Fujimura, Hiroshi Koga, Yasuhiro Nakamura, M. Mochizuki, Zentaro Yamagata   +12 more
openalex   +1 more source

A clinical validation study of RASKET-B: A multiple detection kit for RAS and BRAF gene mutations in colorectal cancer [PDF]

, 2017
Takeshi Kajiwara, Tomohiro Nishina, Hiroya Taniguchi, Kei Muro, Kiwamu Akagi, Hiroki Hara, Tadamichi Denda, Shuichi Hironaka, Toshihiro Kudo, Taroh Satoh, Wataru Okamoto, Takayuki Yoshino   +11 more
openalex   +1 more source

BRAF Inhibitor [PDF]

, 2020
openaire   +1 more source

The Evolution of Pneumocystis jirovecii Pneumonia Prophylaxis for Pediatric Patients With Extracranial Solid Tumors: A Review of Historical Insights and Future Directions

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pneumocystis jirovecii pneumonia (PJP) remains a modern‐day complication for pediatric patients receiving treatment for extracranial solid tumors (ST), highlighting the need for reconsideration of our current approach toward PJP prophylaxis. This critical review aims to evaluate both universal and risk‐stratified approaches to PJP prophylaxis ...
Kriti Kumar, Denise M. Connolly, Ellen Kellington, Elyse Zelunka, Karla Kerrigan, Furqan Shaikh, Paul C. Nathan, Meredith S. Irwin, Sarah Cohen‐Gogo   +8 more
wiley   +1 more source

A CLIP on the Ear: Spitz Melanocytoma Harbouring a CLIP2-BRAF Gene Fusion. [PDF]

Case Rep Dermatol Med
Moutasim KA, Atweh M, Theaker JM.
europepmc   +1 more source

The somatic affairs of BRAF : tailored therapies for advanced malignant melanoma and orphan non-V600E (V600R-M) mutations

, 2013
Giovanni Ponti, Giovanni Pellacani, Aldo Tomasi, Fabio Gelsomino, Andrea Spallanzani, Roberta Depenni, Samer Al Jalbout, Lisa Simi, Lorella Garagnani, Stefania Borsari, Andrea Conti, Cristel Ruini, Annalisa Fontana, Gabriele Luppi   +13 more
openalex   +2 more sources