Results 91 to 100 of about 183,340 (290)
Advanced Science, EarlyView.This study establishes a bio‐electroceutical interface by synergizing engineered exosome‐derived biological signals with electroconductive microneedle‐delivered electrical cues, achieving dual‐pathway reprogramming of the diabetic neurovascular niches and accelerating wound healing. Abstract Diabetic wound healing remains a major clinical challenge due
Di Liu +5 more
wiley +1 more source
Psychiatric disorders and brain-derived neurotrophic factor test: A summary on clinical reports
Journal of the Scientific SocietyBrain-derived neurotrophic factor is a neurotrophin that is related to canonical nerve growth factor (BDNF). The protein BDNF is produced by the human nervous system.
Rujittika Mungmunpuntipantip +1 more
doaj +1 more source
Multiscale Construction, Evaluation, and Application of Organoids
Advanced Science, EarlyView.Organoids are pivotal models with transformative biomedical potential. A comprehensive multi‐scale perspective is presented, encompassing dual‐scale construction, four‐dimensional evaluation, triple‐point application, and an analysis of the current challenges faced by organoid technology, aiming to advance organoid research and its biomedical ...
Wanting Ma +5 more
wiley +1 more source
The effect of exercise intensity on brain derived neurotrophic factor and memory in adolescents
Environmental Health and Preventive Medicine, 2017 Background Brain derived neurotrophic factor (BDNF) seems to serve as an important regulatory mechanism in the growth and development of neurons in many areas of the brain.Insulin-like growth factor 1 (IGF-1) is related to neurogenesis and regulation of ...
Yong Kyun Jeon, Chang Ho Ha
doaj +1 more source
Brain-Derived Neurotrophic Factor, a New Predictor of Coronary Artery Calcification
, 2021 Hong Jin +6 more
openalex +1 more source
Brain-Derived Neurotrophic Factor Signaling in the Pathophysiology of Alzheimer’s Disease: Beneficial Effects of Flavonoids for Neuroprotection [PDF]
, 2021 Tadahiro Numakawa, Haruki Odaka
openalex +1 more source
Advanced Science, EarlyView.A tri‐component biomimetic bioink(gelatin/alginate/fibrinogen) is developed to protect cells in critical pathological environments in AD. Using this bioink, a 3D‐printed NPC construct optimized for hippocampal transplantation is provided to improve cell retention and differentiation in an AD‐like model. This approach enhances memory recovery and offers
Ke Gai +12 more
wiley +1 more source
Advanced Science, EarlyView.ACE can modulate the CBL‐mediated K48 ubiquitination degradation of PSAP by altering its glycosylation levels in NP cells. As a result, NP cells secrete PSAP, which interacts with GPR37 on macrophage surfaces, facilitating their polarization toward the M2 phenotype. These M2 macrophages subsequently secrete TGFβ, which exerts feedback effects on the NP
Youfeng Guo +6 more
wiley +1 more source
Long-Term Deleterious Effects of Short-term Hyperoxia on Cancer Progression—Is Brain-Derived Neurotrophic Factor an Important Mediator? An Experimental Study [PDF]
, 2020 Adrian Tiron +5 more
openalex +1 more source
Advanced Science, EarlyView.TNEA improves cognition in 5xFAD mice by modulating parvalbumin‐positive interneurons in hippocampal CA1. TNEA enhances gamma oscillations during rest and theta power during novel object recognition, restoring excitation/inhibition balance. These findings support TNEA as a minimally invasive therapy for Alzheimer's disease.
Zhongzhao Guo +15 more
wiley +1 more source