Results 101 to 110 of about 249,425 (238)

Psychiatric disorders and brain-derived neurotrophic factor test: A summary on clinical reports

Journal of the Scientific Society
Brain-derived neurotrophic factor is a neurotrophin that is related to canonical nerve growth factor (BDNF). The protein BDNF is produced by the human nervous system.
Rujittika Mungmunpuntipantip, Viroj Wiwanitkit   +1 more
doaj   +1 more source

Targeting bone morphogenetic protein signalling in midbrain dopaminergic neurons as a therapeutic approach in Parkinson's disease. [PDF]

, 2017
Parkinson's disease (PD) is the second most common neurodegenerative disease, characterized by the degeneration of midbrain dopaminergic (mDA) neurons and their axons, and aggregation of α-synuclein, which leads to motor and late-stage cognitive ...
Hegarty, Shane V., O'Keefe, Gerard W., Sullivan, Aideen M.   +2 more
core   +1 more source

Clinical Importance of Serum BDNF (Brain Derived Neurotrophic Factor) Level for the Management of Pregnancies Complicated with Meconium-Stained Amniotic Fluid

Diyala Journal of Medicine
Background: Meconium-stained amniotic fluid complicates pregnancies and is associated with high risk of neonatal meconium aspiration syndrome. Early detection of meconium-stained amniotic fluid is essential to prevent adverse neonatal outcomes ...
Firdaws Midhat Jihad, Esraa Abdulkareem Mohammed   +1 more
doaj   +1 more source

Brain-derived neurotrophic factor: a new adipokine

Biomedical Reviews, 2007
Since leptin discovery in 1994, an extensive body of work has been demonstrating that adipose tissue (mainly its white phenotype) expresses not only metabolic, but also endocrine and paracrine phenotypes, particularly in adipobiology of disease. This new biology is achieved predominantly through secretion of adipokines, which include more than hundred ...
Sornelli F, Fiore M, Chaldakov GN, Aloe L   +3 more
openaire   +2 more sources

Activated Human T Cells, B Cells, and Monocytes Produce Brain-derived Neurotrophic Factor In Vitro and in Inflammatory Brain Lesions: A Neuroprotective Role of Inflammation?

Journal of Experimental Medicine, 1999
Brain-derived neurotrophic factor (BDNF) has potent effects on neuronal survival and plasticity during development and after injury. In the nervous system, neurons are considered the major cellular source of BDNF.
M. Kerschensteiner, E. Gallmeier, L. Behrens, Vivian Vargas Leal, T. Misgeld, W. Klinkert, R. Kolbeck, E. Hoppe, R. Oropeza-Wekerle, I. Bartke, C. Stadelmann, H. Lassmann, H. Wekerle, R. Hohlfeld   +13 more
semanticscholar   +1 more source

Microglia overexpressing brain-derived neurotrophic factor promote vascular repair and functional recovery in mice after spinal cord injury

Neural Regeneration Research
Spinal cord injury represents a severe form of central nervous system trauma for which effective treatments remain limited. Microglia is the resident immune cells of the central nervous system, play a critical role in spinal cord injury. Previous studies
Fanzhuo Zeng, Yuxin Li, Xiaoyu Li, Xinyang Gu, Yue Cao, Shuai Cheng, He Tian, Rongcheng Mei, Xifan Mei   +8 more
doaj   +1 more source

CLINICAL AND DIAGNOSTIC VALUE OF PEROXYNITRITE AND BRAIN-DERIVED NEUROTROPHIC FACTOR IN INFANTS WITH PERINATAL HYPOXIC LESIONS OF THE CNS

Медицинский вестник Юга России, 2013
Purpose: To determine the diagnostic value of peroxynitrite and brain-derived neurotrophic factor in the genesis of perinatal lesions of the central nervous system.Materials and methods: 67 children were comprehensive survey during the first three months
A. A. Afonin, I. G. Loginova, E. A. Papsheva, S. G. Bobrova, N. A. Drukker   +4 more
doaj   +1 more source

Brain Derived Neurotrophic Factor and cognitive markers in subjects with Alzheimer’s disease

Revista Habanera de Ciencias Médicas
Introduction: The brain derived neurotrophic factor is a neurotrophin modulator of cognitive processes. Current studies in Alzheimer’s disease patients show alterations in biomarkers at outlying levels.
Naybí Prendes Rivero, Levis Verde Corvo, Belkis López González, Iris Dany Carmenate Rodríguez, Nibaldo B Mesa Hernández, María A Robinson Agramonte   +5 more
doaj  

Reduced mesencephalic astrocyte–derived neurotrophic factor expression by mutant androgen receptor contributes to neurodegeneration in a model of spinal and bulbar muscular atrophy pathology

Neural Regeneration Research
Spinal and bulbar muscular atrophy is a neurodegenerative disease caused by extended CAG trinucleotide repeats in the androgen receptor gene, which encodes a ligand-dependent transcription factor.
Yiyang Qin, Wenzhen Zhu, Tingting Guo, Yiran Zhang, Tingting Xing, Peng Yin, Shihua Li, Xiao-Jiang Li, Su Yang   +8 more
doaj   +1 more source

Diversity of Microglia-Derived Molecules with Neurotrophic Properties That Support Neurons in the Central Nervous System and Other Tissues

Molecules
Microglia, the brain immune cells, support neurons by producing several established neurotrophic molecules including glial cell line-derived neurotrophic factor (GDNF) and brain-derived neurotrophic factor (BDNF).
Kennedy R. Wiens, Naved Wasti, Omar Orlando Ulloa, Andis Klegeris   +3 more
doaj   +1 more source