Results 101 to 110 of about 236,444 (370)
Advanced Healthcare Materials, EarlyView.The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley +1 more source
Human umbilical cord mesenchymal stem cells promote peripheral nerve repair via paracrine mechanisms
Neural Regeneration Research, 2015 Human umbilical cord-derived mesenchymal stem cells (hUCMSCs) represent a promising young-state stem cell source for cell-based therapy. hUCMSC transplantation into the transected sciatic nerve promotes axonal regeneration and functional recovery.
Zhi-yuan Guo +4 more
doaj +1 more source
PLoS ONE, 2016 Background The mechanisms through which physical activity supports healthy brain function remain to be elucidated. One hypothesis suggests that increased brain-derived neurotrophic factor (BDNF) mediates some cognitive and mood benefits.
Adam Dinoff +6 more
semanticscholar +1 more source
The Brain Derived Neurotrophic Factor and Personality [PDF]
Advances in Biology, 2014 The study of the biological basis of personality is a timely research endeavor, with the aim of deepening our understanding of human nature. In recent years, a growing body of research has investigated the role of the brain derived neurotrophic factor (BDNF) in the context of individual differences across human beings, with a focus on personality ...
openaire +2 more sources
Population Genetic Study of the Brain-Derived Neurotrophic Factor (BDNF) Gene [PDF]
, 2011 Genetic variants in the brain-derived neurotrophic factor (BDNF) gene, predominantly the functional Val66Met polymorphism, have been associated with risk of bipolar disorder and other psychiatric disorders. However, not all studies support these findings,
Aldinger, Kimberly A. +8 more
core +1 more source
Advanced Healthcare Materials, EarlyView.Granular hydrogels are emerging microporous platforms for cell culture and delivery, showing great potential for replicating the complex, heterogeneous environments found in natural tissues. This review outlines the design principles of granular hydrogels, highlighting critical factors that determine the final physicochemical properties of the entire ...
Shuhan Feng, Kaiyang Chen, Shiqi Wang
wiley +1 more source
Current Neuropharmacology, 2016 Depression is the most prevalent and among the most debilitating of psychiatric disorders. The precise neurobiology of this illness is unknown. Several lines of evidence suggest that peripheral and central inflammation plays a role in depressive symptoms,
Ji-chun Zhang, W. Yao, K. Hashimoto
semanticscholar +1 more source
Role of the brain‐derived neurotrophic factor at glutamatergic synapses [PDF]
British Journal of Pharmacology, 2008 The neurotrophin brain‐derived neurotrophic factor (BDNF) plays an important role in the activity‐dependent regulation of synaptic structure and function, particularly of the glutamatergic synapses. BDNF may be released in the mature form, which activates preferentially TrkB receptors, or as proBDNF, which is coupled to the stimulation of the p75NTR ...
Carvalho, A. L. +3 more
openaire +3 more sources
Brain-derived neurotrophic factor stimulates energy metabolism in developing cortical neurons. [PDF]
, 2003 Brain-derived neurotrophic factor (BDNF) promotes the biochemical and morphological differentiation of selective populations of neurons during development.
Allaman, I. +4 more
core +1 more source
Wireless Acousto‐Piezoelectric Conduit with Aligned Nanofibers for Neural Regeneration
Advanced Materials, EarlyView.An ultrasound‐driven, highly aligned piezoelectric nanofiber‐based nerve guidance conduit (APNF‐NGC) designed for effective peripheral nerve repair has been demonstrated in this study. Featuring aligned topology, cell‐adhesive surfaces, and an axial electric field, the APNF‐NGC collectively promotes significant nerve regeneration.
Sera Jeon +8 more
wiley +1 more source