Results 121 to 130 of about 183,340 (290)

Leveraging the Mononuclear Phagocyte System for Advancing Glioma Theranostics: Current Insights and Future Directions

Aggregate, EarlyView.
Mononuclear phagocytic cells with their natural ability to cross the blood brain barrier may provide new possibilities for glioma diagnosis and treatment. This review focused on mechanistic insights of the role of mononuclear phagocyte system (MPS) in central nerve system and glioma development, as well as the critical evaluation of development ...
Wenhui Wang, Ruijing Wen, Qianbei Li, Zhen Cai, Zihao Ou, Lei Zheng   +5 more
wiley   +1 more source

Investigating the Role of BDNF in Insomnia: Current Insights

Nature and Science of Sleep, 2023
Marta Ditmer,* Agata Gabryelska,* Szymon Turkiewicz, Marcin Sochal Department of Sleep Medicine and Metabolic Disorders, Medical University of Lodz, Lodz, 92-215, Poland*These authors contributed equally to this workCorrespondence: Marcin ...
Ditmer M, Gabryelska A, Turkiewicz S, Sochal M   +3 more
doaj  

Growth Standards for Children With Smith–Magenis Syndrome (SMS)

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Smith–Magenis syndrome (SMS, OMIM 182290) is a complex syndromic diagnosis marked by neurobehavioral differences and distinct facial dysmorphisms, caused by haploinsufficiency of the retinoic acid‐1 (RAI1) gene either by a pathogenic sequence variant or deletion at chromosome 17p11.2 involving a portion or all of this gene.
Julie Hoover‐Fong, John McGready, Leah Fleming, Kerry Schulze, Folami Duncan, Alexis Leonard, Marie Christine de Blois Boucard, Danilo Moretti‐Ferreira, Andrea L. Gropman, Wendy J. Introne, Ann C. M. Smith   +10 more
wiley   +1 more source

PROTECTIVE EFFECTS OF SPIRULINA MICROALGAE AGAINST ADOLESCENT STRESS-INDUCED OXIDATIVE STRESS, BRAIN-DERIVED NEUROTROPHIC FACTOR ALTERATIONS AND MORPHOLOGICAL REMODELING IN THE PREFRONTAL CORTEX OF ADULT FEMALE RATS

, 2023
Nasrollah Moradikor, Motahareh Haghipanah, Ali Rashidy‐Pour   +2 more
openalex   +1 more source

Treg Cells Modulate Neuroinflammation and Behavioral Deficits in Autism: Evidence From MR‐Based Genetic Analyses and Experimental Models

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental condition that is increasingly linked to immune dysfunction and neuroinflammation. Regulatory T cells (Tregs), which are crucial in maintaining immune homeostasis, have been implicated in the pathogenesis of ASD.
Zuqing Nie, Xinyi Xu, Junhao Chen, Huiling Chen, Meng Li, Yang Zhang, Zhiwei Li, Chen Shen, Jie Wen, Xia Cao   +9 more
wiley   +1 more source

Electrophysiological correlates of the brain-derived neurotrophic factor (BDNF) Val66Met polymorphism [PDF]

, 2020
Nikita Roy, Robert J. Barry, Francesca Fernandez, Chai K. Lim, Mahmoud A. Al‐Dabbas, Diana Karamacoska, Samantha J. Broyd, Nadia Solowij, Christine L. Chiu, Genevieve Z. Steiner   +9 more
openalex   +1 more source

Transplanting neural stem cells overexpressing miRNA‐21 can promote neural recovery after cerebral hemorrhage through the SOX2/LIN28‐let‐7 signaling pathway

Animal Models and Experimental Medicine, EarlyView.
Abstract Background Intracerebral hemorrhage (ICH) remains a devastating neurological disorder with limited therapeutic options. Neural stem cell (NSC)‐based therapies have emerged as a potential regenerative approach, yet the molecular mechanisms regulating NSC behavior require further elucidation.
Wei Dai, Yongxia Li, Jiarui Du, Gang Shen, Meimei Fan, Zuopeng Su, Fulin Xu, Fang Yuan   +7 more
wiley   +1 more source

Continuous decrease in serum brain-derived neurotrophic factor (BDNF) levels in a neuropsychiatric syndrome of systemic lupus erythematosus patient with organic brain changes

Neuropsychiatric Disease and Treatment, 2008
Atsuko Ikenouchi-Sugita, Reiji Yoshimura, Nobuhisa Ueda, Yuki Kodama, Wakako Umene-Nakano, Jun NakamuraDepartment of Psychiatry, School of Medicine, University of Occupational and Environmental Health, Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka ...
Atsuko Ikenouchi-Sugita, Reiji Yoshimura, Nobuhisa Ueda, Yuki Kodama, Wakako Umene-Nakano, Jun Nakamura   +5 more
doaj  

Impact of low dose nicotine on brain-derived neurotrophic factor after global hypoxia in newborn piglets

Journal of Perinatal Medicine
The aim of this study was to assess the effect of low-dose nicotine on the expression of brain-derived neurotrophic factor (BDNF) mRNA, its antisense alternative splice form brain-derived neurotrophic factor antisense (BDNF-AS), and its protein levels ...
Vølstad Karianne B., Melheim Maria, Iversen Marie H., Stiris Tom, Saugstad Ola D., Baumbusch Lars O., Andresen Jannicke H.   +6 more
doaj   +1 more source

A potential strategy for improving offspring behavior in maternal immune activation: Amantadine‐mediated suppression of neuroinflammation

Animal Models and Experimental Medicine, EarlyView.
Amantadine (AMA) regulates neurocyte apoptosis and inhibits neurocyte inflammation to prevent maternal immune activation (MIA) from affecting offspring behavior. Abstract Background Maternal viral infection during pregnancy can lead to maternal immune activation (MIA), increasing the risk of neurodevelopmental disorders in offspring.
Jianfei Wu, Yu Liu, Binglong Wang, Yilin Wang, Bo Liu, Youguo Tan, Duanfang Cai, Kezhi Liu, Daixu Wei   +8 more
wiley   +1 more source