Results 141 to 150 of about 187,908 (321)

RGS14 (414)-mediated prevention of an episodic memory loss: a study of molecular mechanism [PDF]

, 2015
A large proportion of human populations suffer memory impairments either caused by normal aging or afflicted by diverse neurological and neurodegenerative diseases. Memory enhancers and other drugs tested so far against memory loss have failed to produce
Navarro Lobato, Irene
core   +1 more source

Immunoaffinity‐Mimetic Assembly of Peptide‐Aptamer Conjugates and Stem Cell‐Derived Exosomes into Hierarchical Microgels for Spinal Cord Injury Repair

Advanced Science, EarlyView.
Inspired by antibody‐antigen binding, this study develops an unprecedented immunoaffinity‐mimetic assembly strategy, with Peptide‐AptCD63 conjugates acting as antibody surrogates binding CD63 epitopes on mesenchymal stem cell‐derived exosomes. This creates a hierarchical microstructure intended to synergistically integrate antioxidative and anti ...
Dantong Zheng, Yuxin Bai, Zhibo Liu, Zinan Zhao, Yiming Kong, Yao Xu, Qi Jia, Rongrong Zhu, Yong Hu   +8 more
wiley   +1 more source

Migrasomes in Ischemic Stroke: Molecular Landscape and Pathophysiological Impact

Advanced Science, EarlyView.
Multi‐omics profiling of stroke patients exposes systemic molecular fingerprints of immune activation, oxidative stress and metabolic collapse. Complement and coagulation cascade, and cholesterol metabolism emerge as shared functional hallmarks of plasma migrasomes in stroke patients and migrasomes isolated from experimental stroke mice.
Huifen Zhou, Yingying Zhang, Peng Zhou, Haofang Wan, Lingling Li, Bin Xu, Yuping Wan, Yingming Song, Yi Kang, Hongbo Zhang, Min Shi, Qun Hou, Jiehong Yang, Chen Ding, Wei Fu, Buchang Zhao, Haitong Wan   +16 more
wiley   +1 more source

Identification of the isoforms of Ca²⁺/calmodulin‐dependent protein kinase II and expression of brain‐derived neurotrophic factor mRNAs in the substantia nigra [PDF]

, 2005
Akifumi Kamata, Yusuke Takeuchi, Kohji Fukunaga   +2 more
openalex   +1 more source

Diet transition to a high-fat diet for 3 weeks reduces brain omega-3-fatty acid levels, alters BDNF signaling and induces anxiety & depression-like behavior in adult rats [PDF]

, 2012
Background: The consumption of diets high in calories and low in nutrient value is becoming increasingly common in modern society, which can lead to metabolic disorders like diabetes and obesity, and potentially to psychiatric disorders.
Fernando Gomez-Pinilla, Sandeep Sharma, Yumei Zhuang   +2 more
core   +1 more source

Growth Standards for Children With Smith–Magenis Syndrome (SMS)

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Smith–Magenis syndrome (SMS, OMIM 182290) is a complex syndromic diagnosis marked by neurobehavioral differences and distinct facial dysmorphisms, caused by haploinsufficiency of the retinoic acid‐1 (RAI1) gene either by a pathogenic sequence variant or deletion at chromosome 17p11.2 involving a portion or all of this gene.
Julie Hoover‐Fong, John McGready, Leah Fleming, Kerry Schulze, Folami Duncan, Alexis Leonard, Marie Christine de Blois Boucard, Danilo Moretti‐Ferreira, Andrea L. Gropman, Wendy J. Introne, Ann C. M. Smith   +10 more
wiley   +1 more source

Impact of low dose nicotine on brain-derived neurotrophic factor after global hypoxia in newborn piglets

Journal of Perinatal Medicine
The aim of this study was to assess the effect of low-dose nicotine on the expression of brain-derived neurotrophic factor (BDNF) mRNA, its antisense alternative splice form brain-derived neurotrophic factor antisense (BDNF-AS), and its protein levels ...
Vølstad Karianne B., Melheim Maria, Iversen Marie H., Stiris Tom, Saugstad Ola D., Baumbusch Lars O., Andresen Jannicke H.   +6 more
doaj   +1 more source

EFFECTS OF BRAIN-DERIVED NEUROTROPHIC FACTOR AND ITS SIGNALING PATHWAY ON SENSORY NEURONAL ACTIVATION DURING COLITIS

, 2015
Fiza Hashmi
openalex   +2 more sources

Brain-Derived Neurotrophic Factor: Concepts and Concerns in Clinical Chemistry: a Short Review

, 2021
Sora Yasri, Viroj Wiwanitkit, M Notaras, M Van Den Buuse, C Zuccato, E Cattaneo, L Iughetti, L Lucaccioni, F Fugetto, B Predieri, A Berardi, F Ferrari, P Di Carlo, G Punzi, G Ursini, B Lima Giacobbo, J Doorduin, H Klein, R Dierckx, E Bromberg, E De Vries, L Wang, J Li, L Yu, Y Xiao, R Huang, H Kuang, B Hai, B, H Kurku, M Soran, A Yar, N Akdam, Arslan, M Gnen, C Sekerci, Y Tanidir, T Toprak, B Basok, F Isman, F Simsek, C Akbal, T Tarcan, P Smeele, S Almeida, C Meiller, A.-L Chn, C Liddell, L Cellerin, F Montagne, S Deshayes, S Benziane, M.-C Copin, P Hofman, F Le Pimpec-Barthes, H Porte, A Scherpereel, M Grgoire, D Jean, C Blanquart, B Duysinx, A Paulus, V Heinen, D Nguyen, M Henket, J Corhay, R Louis, A Mandel, H Ozdener, V Utermohlen, M Miranda, J Morici, M Zanoni, P Bekinschtein, Y Naegelin, H Dingsdale, K Suberli, S Schdelin, L Kappos, Y Barde, P Gaub, A De Lon, J Gibon, V Soubannier, G Dorval, P Sgula, P Barker, B Riffault, N Kourdougli, C Dumon, N Ferrand, E Buhler, F Schaller, C Chambon, C Rivera, J Gaiarsa, C Porcher, B Michalski, M Fahnestock, T Shen   +99 more
openalex   +1 more source

Treg Cells Modulate Neuroinflammation and Behavioral Deficits in Autism: Evidence From MR‐Based Genetic Analyses and Experimental Models

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental condition that is increasingly linked to immune dysfunction and neuroinflammation. Regulatory T cells (Tregs), which are crucial in maintaining immune homeostasis, have been implicated in the pathogenesis of ASD.
Zuqing Nie, Xinyi Xu, Junhao Chen, Huiling Chen, Meng Li, Yang Zhang, Zhiwei Li, Chen Shen, Jie Wen, Xia Cao   +9 more
wiley   +1 more source