Brain derived neurotrophic factor and secreted amyloid precursor protein-α response to moderate and high intensity exercise. [PDF]
Spencer FSE+5 more
europepmc +1 more source
Intratumoral Nerve Phased Development: A Promising Therapeutic Target
ABSTRACT The nervous system has emerged as a critical regulator of tumor biology, engaging in dynamic crosstalk with cancer cells. Although the protumorigenic role of innervation is well established, increasing attention is now directed toward reciprocal influences—how tumors actively shape and remodel local nerve networks within the tumor ...
Xiangxian Che+3 more
wiley +1 more source
Potential of Nerve Growth Factor (NGF)- and Brain-Derived Neurotrophic Factor (BDNF)-Targeted Gene Therapy for Alzheimer's Disease: A Narrative Review. [PDF]
Koya PC, Kolla SC, Madala V, Sayana SB.
europepmc +1 more source
Allogeneic Bone Marrow‐Derived Mesenchymal Stem Cells for Parkinson's Disease: A Randomized Trial
Abstract Background Neuroinflammation contributes to Parkinson's disease (PD) progression and motor dysfunction. Allogeneic human mesenchymal stem cells (allo‐hMSCs) may reduce neuroinflammation and improve motor symptoms. Objectives To evaluate the efficacy of repeated intravenous doses of 10 × 106/kg allo‐hMSCs in improving motor symptoms in patients
Mya C. Schiess+15 more
wiley +1 more source
Bioelectric stimulation outperforms brain derived neurotrophic factor in promoting neuronal maturation. [PDF]
Diego-Santiago MDP+6 more
europepmc +1 more source
ABSTRACT Neuropsychiatric disorders present a multifaceted challenge, characterized by cognitive, social, and motor impairments with manifold underlying mechanisms. Recent attention has turned to epigenetic mechanisms, particularly histone lysine methyltransferases (HKMTs), such as G9a, in understanding fundamental pathogenesis.
Malak Hajar+4 more
wiley +1 more source
Brain-derived neurotrophic factor drives muscle adaptation similar to aerobic training in mice. [PDF]
Brown AD+11 more
europepmc +1 more source
Nano‐biosensors offer real‐time monitoring of cognitive and emotional states through biomarkers like cortisol and dopamine. They enhance personalized learning, mental health interventions, and daily performance across sectors. Integrated into wearables and IoT, they promise a transformative impact while raising ethical, technological, and regulatory ...
Priscilla Adomako Gyasi+6 more
wiley +1 more source
Low-Cost, Disposable Biosensor for Detection of the Brain-Derived Neurotrophic Factor Biomarker in Noninvasively Collected Saliva toward Diagnosis of Mental Disorders. [PDF]
Gomes NO+5 more
europepmc +1 more source