Results 281 to 290 of about 236,444 (370)

Intratumoral Nerve Phased Development: A Promising Therapeutic Target

open access: yesMedicine Bulletin, EarlyView.
ABSTRACT The nervous system has emerged as a critical regulator of tumor biology, engaging in dynamic crosstalk with cancer cells. Although the protumorigenic role of innervation is well established, increasing attention is now directed toward reciprocal influences—how tumors actively shape and remodel local nerve networks within the tumor ...
Xiangxian Che   +3 more
wiley   +1 more source

Allogeneic Bone Marrow‐Derived Mesenchymal Stem Cells for Parkinson's Disease: A Randomized Trial

open access: yesMovement Disorders, EarlyView.
Abstract Background Neuroinflammation contributes to Parkinson's disease (PD) progression and motor dysfunction. Allogeneic human mesenchymal stem cells (allo‐hMSCs) may reduce neuroinflammation and improve motor symptoms. Objectives To evaluate the efficacy of repeated intravenous doses of 10 × 106/kg allo‐hMSCs in improving motor symptoms in patients
Mya C. Schiess   +15 more
wiley   +1 more source

Bioelectric stimulation outperforms brain derived neurotrophic factor in promoting neuronal maturation. [PDF]

open access: yesSci Rep
Diego-Santiago MDP   +6 more
europepmc   +1 more source

Targeting Histone H3K9 Methyltransferase G9a as a Potential Therapeutic Strategy for Neuropsychiatric Disorders

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Neuropsychiatric disorders present a multifaceted challenge, characterized by cognitive, social, and motor impairments with manifold underlying mechanisms. Recent attention has turned to epigenetic mechanisms, particularly histone lysine methyltransferases (HKMTs), such as G9a, in understanding fundamental pathogenesis.
Malak Hajar   +4 more
wiley   +1 more source

Brain-derived neurotrophic factor drives muscle adaptation similar to aerobic training in mice. [PDF]

open access: yesFASEB J
Brown AD   +11 more
europepmc   +1 more source

Nano‐Biosensors for Continuous Cognitive and Stress Monitoring: Applications in Learning and Mental Well‐Being

open access: yesNano Select, EarlyView.
Nano‐biosensors offer real‐time monitoring of cognitive and emotional states through biomarkers like cortisol and dopamine. They enhance personalized learning, mental health interventions, and daily performance across sectors. Integrated into wearables and IoT, they promise a transformative impact while raising ethical, technological, and regulatory ...
Priscilla Adomako Gyasi   +6 more
wiley   +1 more source

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