Results 311 to 320 of about 236,444 (370)

Biomaterial‐Based Emergency Intervention for Secondary Spinal Cord Injury

open access: yesSmall Science, EarlyView.
Emergency intervention using advanced biomaterials targets key pathological mechanisms to block secondary spinal cord injury (SCI) by inhibiting inflammation, reducing excitotoxicity, restoring the blood−spinal cord barrier, and limiting scar formation, which provides significant neural protection and promotes neural regeneration, offering promising ...
Jincheng Li   +5 more
wiley   +1 more source

Design of the Hydrophobic Core of Self‐Assembling Peptide Fibrils for Enhanced Neural Regeneration

open access: yesSmall Science, EarlyView.
This study reports the design of neurosupportive peptide fibrils by systematically varying the hydrophobic core of EF‐C‐derived peptide variants. Peptides containing phenylalanine or isoleucine side chains are identified as having high aggregation propensities and performing superior in cell culture studies.
Yu‐Liang Tsai   +9 more
wiley   +1 more source

Developments of Thermosensitive Hydrogel for Maxillofacial Bone Regeneration

open access: yesSmall Science, EarlyView.
Thermosensitive hydrogel with seed cells and growth factors presents a new method for bone regeneration, changing states with temperature and offering fluidity, injectability, and controlled drug release. This article reviews thermosensitive hydrogel's role in angiogenesis, neurogenesis, and osteogenesis in maxillofacial bone regeneration and discusses
Qinrou Zhang   +11 more
wiley   +1 more source

Circadian rhythm of brain-derived neurotrophic factor in serum and plasma. [PDF]

open access: yesExp Physiol
Ehrhardt M   +8 more
europepmc   +1 more source

Neuroprotective effects of remote limb ischemic preconditioning through enhanced cerebral blood flow via activation of the PI3K/AKT pathway in ischemic stroke

open access: yesVIEW, EarlyView.
Stroke is a leading cause of death and disability worldwide, often due the inadequate restoration of cerebral blood flow following vascular recanalization. Our study demonstrates that a simple technique called RLIPC (remote limb ischemic preconditioning), which involves briefly restricting blood flow in a limb, protects the brain during a stroke by ...
Chaoran Dou   +8 more
wiley   +1 more source

Nanotechnology and cell death: Revolutionizing disease treatment with nanoparticle strategies

open access: yesVIEW, EarlyView.
Traditional disease treatments often face issues such as poor drug targeting and significant side effects, with many complex diseases lacking effective therapies. Our research utilizes tiny nanomaterials to treat diseases by regulating natural cell death processes, improving the immune environment, etc., enabling drugs to act more precisely.
Yiwen Wan   +6 more
wiley   +1 more source

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