Results 321 to 330 of about 236,444 (370)

Plasma brain-derived neurotrophic factor before hemodialysis reduces the risk of depression in patients with chronic renal failure. [PDF]

open access: yesRen Fail
Suárez-Cuenca JA   +13 more
europepmc   +1 more source

Sevoflurane induces the inattention, cognitive impairment, and motor dysfunction by hypermethylation of retinoic acid receptor α in the medial prefrontal cortex of neonatal mice

open access: yesVIEW, EarlyView.
The mechanisms underlying neurodevelopmental toxicity induced by repeated exposure to general anesthesia in neonatal mice remain to be fully elucidated. In this study, neonatal mice were exposed to sevoflurane on postnatal days 6, 8, and 10. On postnatal day 30, the medial prefrontal cortex was collected for whole‐genome bisulfite sequencing and RNA ...
Yu Hou   +10 more
wiley   +1 more source

TSP50 in Neural Stem Cells Regulates Aging‐Related Cognitive Decline and Neuroinflammation by Altering the Gut Microbiota

open access: yesAging Cell, EarlyView.
TSP50 expression declines in the hippocampus of aged humans and mice. TSP50 deficiency in NSCs accelerates mouse aging, causing cognitive impairments and neuroinflammation. Restoring gut microbiota via FMT and TSP50 overexpression alleviates these phenotypes. Our study shows TSP50's critical role in aging and gut microbiota as a key mediator.
Xiaoli Li   +15 more
wiley   +1 more source

Rat models of fetal alcohol spectrum disorders for studying the critical role of cerebellar damage: A scoping review

open access: yesAlcohol, Clinical and Experimental Research, EarlyView.
In rat models used to study the effects of early alcohol exposure on cerebellum function and structure during pregnancy and lactation, the following conclusions can be drawn: (1) Exposure to ethanol during the first and second‐trimester equivalent in humans affects biochemical pathways in the cerebellum, but produces fewer structural changes.
Fátima Nogales   +5 more
wiley   +1 more source

Cognitive and Psychomotor Processing Speed in Medication‐Naïve Individuals With First‐Episode of Psychosis: The Role of Peripheral Inflammatory Markers

open access: yesActa Psychiatrica Scandinavica, EarlyView.
ABSTRACT Background and Hypothesis Deficits in processing speed (PS) and psychomotor speed (PMS) are core cognitive impairments in schizophrenia spectrum disorders, including first‐episode psychosis (FEP). Neuroinflammation has been proposed as a potential contributor to these deficits.
Ángel Yorca‐Ruiz   +8 more
wiley   +1 more source

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