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Brain Derived Neurotrophic Factor

2014
Brain-derived neurotrophic factor (BDNF), is a member of neurotrophin family having roles in survival, growth and function of neurons in the central and peripheral nervous system. BDNF mRNA and protein levels have been identified in the cerebellum, hippocampus, bulbus olfactorius, spinal cord, thalamus, prefrontal cerebral cortex, hypothalamus ...
YARIM, Gül, KAZAK, Filiz
openaire   +3 more sources

Brain-derived neurotrophic factor.

Growth factors (Chur, Switzerland), 2005
Since the purification of BDNF in 1982, a great deal of evidence has mounted for its central roles in brain development, physiology, and pathology. Aside from its importance in neural development and cell survival, BDNF appears essential to molecular mechanisms of synaptic plasticity.
Devin K, Binder, Helen E, Scharfman
openaire   +1 more source

Brain‐derived neurotrophic factor and post‐stroke depression

Journal of Neuroscience Research, 2019
Brain‐derived neurotrophic factor (BDNF) is well known to play a critical role in cognition. Its role in mood disorders, including post stroke depression (PSD), is also recognized with more evidence surfacing. In patients with PSD, their serum BNDF level
Eric T. Zhang, Ping Liao
semanticscholar   +1 more source

Brain-derived neurotrophic factor in multiple sclerosis

Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova, 2019
The review presents data on brain-derived neurotrophic factor (BDNF), its structure and functions, the effect on the pathogenesis of experimental autoimmune encephalomyelitis and multiple sclerosis (MS). The correlation of BDNF level with clinical manifestations of MS and the changes of its level during disease-modifying therapy is considered.
A A, Semkina   +4 more
openaire   +2 more sources

Brain-Derived Neurotrophic Factor (BDNF): Novel Insights into Regulation and Genetic Variation

The Neuroscientist, 2018
Since its discovery, brain-derived neurotrophic factor (BDNF) has spawned a literature that now spans 35 years of research. While all neurotrophins share considerable overlap in sequence homology and their processing, BDNF has become the most widely ...
M. Notaras, M. van den Buuse
semanticscholar   +1 more source

Brain-derived neurotrophic factor in neurodegenerative diseases

Nature Reviews Neurology, 2009
Changes in the levels and activities of neurotrophic factors, such as brain-derived neurotrophic factor (BDNF), have been described in a number of neurodegenerative disorders, including Huntington disease, Alzheimer disease and Parkinson disease. It is only in Huntington disease, however, that gain-of-function and loss-of-function experiments have ...
C. Zuccato, E. Cattaneo
openaire   +2 more sources

Brain-derived neurotrophic factor in romantic attachment.

Psychological medicine, 2009
Social attachment is fundamental for its relevant impact upon survival and reproduction in several animals and particularly so in humans. Recently, much research efforts have been directed towards the understanding of the neurobiological basis of social attachment.
MARAZZITI D   +8 more
openaire   +3 more sources

Molecular cloning and expression of brain-derived neurotrophic factor

Nature, 1989
J. Leibrock   +7 more
semanticscholar   +1 more source

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