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The Brain-Gut Axis in Health and Disease
2014The interaction between the brain and the gut has been recognized for many centuries. This bidirectional interaction occurs via neural, immunological and hormonal routes, and is important not only in normal gastrointestinal function but also plays a significant role in shaping higher cognitive function such as our feelings and our subconscious decision-
Yasser, Al Omran, Qasim, Aziz
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The Brain-Gut Axis and the Gender
2019The term brain-gut axis depicts an anatomic and functional substrate in which the brain and psychosocial factors influence the GI tract and vice versa. The hardwiring between the brain and gut is mainly, but not solely, represented by a complex integrated circuitry that exchanges information from emotional and cognitive centers of the brain to the ...
Giovanni Barbara +4 more
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Brain-Gut-Microbiota Axis and Mental Health
Psychosomatic Medicine, 2017ABSTRACT Objective The brain-gut-microbiota axis has been put forward as a new paradigm in neuroscience, which may be of relevance to mental illness. The mechanisms of signal transmission in the brain-gut-microbiota axis are complex and involve bidirectional communications that enable gut microbes to communicate with ...
Timothy G. Dinan, John F. Cryan
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The Future of Probiotics for Disorders of the Brain-Gut Axis
2014Probiotics, or at the very least products that might have probiotic properties, have been with us for decades, if not centuries, but it has only been in recent years that they have been subjected to serious scientific study. This surge in interest in probiotics has coincided with the era of the microbiome; as more and more is understood about the gut ...
Eamonn M M, Quigley, Fergus, Shanahan
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Bombesin and the brain-gut axis.
Peptides, 2001Bombesin is the first peptide shown to act in the brain to influence gastric function and the most potent peptide to inhibit acid secretion when injected into the cerebrospinal fluid (CSF) in rats and dogs. Bombesin responsive sites include specific hypothalamic nuclei (paraventricular nucleus, preoptic area and anterior hypothalamus), the dorsal vagal
V, Martinez, Y, Taché
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Gastroenterologie clinique et biologique, 2010
There is a bidirectional relation between the central nervous system and the digestive tract, i.e., the brain-gut axis. Numerous data argue for a dysfunction of the brain-gut axis in the pathophysiology of irritable bowel syndrome (IBS). Visceral hypersensitivity is a marker of IBS as well as of an abnormality of the brain-gut axis.
B, Bonaz, J-M, Sabate
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There is a bidirectional relation between the central nervous system and the digestive tract, i.e., the brain-gut axis. Numerous data argue for a dysfunction of the brain-gut axis in the pathophysiology of irritable bowel syndrome (IBS). Visceral hypersensitivity is a marker of IBS as well as of an abnormality of the brain-gut axis.
B, Bonaz, J-M, Sabate
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Understanding Microbial Mediation of the Brain-Gut Axis
Gastroenterology Clinics of North AmericaBidirectional communications between the gut and the brain play an important role in the regulation of food intake, pain perception, mood, and cognitive function. The involved communication pathways are modulated by signals generated by the gut microbiome.
Jill A, Horn +2 more
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The pathogenesis of obesity: Stress and the brain-gut axis
Surgery for Obesity and Related Diseases, 2005Energy balance, stress, and eating It has become fashionable to view the world through “stress-colored glasses” as new technology has enabled studies of molecular pathways and functional neuroimaging. The thesis of this review is that any challenge to the nutritional integrity of any form of life is the most important stressor and the ultimate stimulus
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Prostaglandins and brain-gut axis.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2008Prostaglandins (PGs) have well documented physiological and pharmacological actions on the gastrointestinal (GI) tract. This communication reviews the evidence for peripheral and central nervous system (CNS) physiological actions of PGs in order to determine their role in the brain-gut axis, if any.
E Z, Dajani, T G, Shahwan, N E, Dajani
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Microbiota-Brain-Gut Axis and Neurodegenerative Diseases
Current Neurology and Neuroscience Reports, 2017The purposes of this review were as follows: first, to provide an overview of the gut microbiota and its interactions with the gut and the central nervous system (the microbiota-gut-brain axis) in health, second, to review the relevance of this axis to the pathogenesis of neurodegenerative diseases, such as Parkinson's disease, and, finally, to assess ...
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