Results 81 to 90 of about 6,869,970 (289)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

The ‘Little Ice Age’ in the Southern Hemisphere in the context of the last 3000 years : Peat-based proxy-climate data from Tierra del Fuego [PDF]

open access: yes, 2014
DM’s research (at Department of Earth Sciences, Uppsala University) was supported through a European Community Marie Curie Fellowship (Contract HPMF-CT-2000-01056).Peer ...
Brain, Sally A.   +4 more
core   +2 more sources

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

SSVEP-Based Brain-Computer Interface Controlled Robotic Platform With Velocity Modulation [PDF]

open access: diamond, 2023
Yue Zhang   +5 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Financial Engineering and Rationality: Experimental Evidence Based on the Monty Hall Problem [PDF]

open access: yes
Financial engineering often involves redefining existing financial assets to create new financial products. This paper investigates whether financial engineering can alter the environment so that irrational agents can quickly learn to be rational.
Brain Kluger, Daniel Friedman
core  

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

La segregación, los guetos y la integración social urbana: mitos y claves

open access: yesEURE (Santiago) - Revista Latinoamericana de Estudios Urbano Regionales, 2008
Predominan en el medio académico y político las nociones "naturalistas" sobre la segregación social del espacio en las ciudades latinoamericanas. Las desigualdades o el "clasismo", hechos fuertes y persistentes, harían de la segregación algo inevitable ...
FRANCISCO SABATINI, ISABEL BRAIN
doaj  

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