Results 81 to 90 of about 4,854,049 (293)

Do sleep difficulties exacerbate deficits in sustained attention following traumatic brain injury? [PDF]

, 2010
Sustained attention has been shown to be vulnerable following traumatic brain injury (TBI). Sleep restriction and disturbances have been shown to negatively affect sustained attention. Sleep disorders are common but under-diagnosed after TBI.
Espie, C.A., Bloomfield, I.L.M., Espie, CA, Evans, J.J., Bloomfield, IL, Evans, JJ   +5 more
core   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Enlarged infarct volume and loss of BDNF mRNA induction following brain ischemia in mice lacking FGF-2 [PDF]

, 2006
FGF-2, a potent multifunctional and neurotrophic growth factor, is widely expressed in the brain and upregulated in cerebral ischemia. Previous studies have shown that intraventricularly or systemically administered FGF-2 reduces the size of cerebral ...
Kiprianova, Irina, Dono, Rosanna, Schindowski, Katharina, Krause, Sonja, Bohlen und Halbach, Oliver von, Schwaninger, Markus, Unsicker, Klaus   +6 more
core   +1 more source

Conceptual approaches to the treatment of neurosurgical pathology (based on examples of chronic subdural hematomas and severe brain contusions)

Клинический разбор в общей медицине
Introduction. General development tendency for modern neurosurgery is characterized by neuroimaging of focal brain damage at an early stage, choice of conceptual approaches to treatment tactics and minimization of operative interventions themselves ...
Leonid B. Likhterman, Vladimir A. Okhlopkov, Alexander D. Kravchuk, Boleslav L. Lichterman   +3 more
doaj   +1 more source

Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu, Xiaoning Ren, Cuihua Fan, Chun Li, Lijie Zhang, Zaiqiang Zhang, Shaowu Li, Zhongmeng Lai, Bin Cai, Ying Fu, Yi Lin, Zhibao Zhu   +11 more
wiley   +1 more source

Emotion recognition in chronic treatment-resistant depression : before and after neurosurgical treatment [PDF]

, 2013
The neuroanatomical structures underlying Major Depressive Disorder (MDD) are not fully understood. Invasive treatment options now exist that target the brain structures associated with MDD.
Grant, Frazer Alexander Lockhart
core   +2 more sources

The effects of the dopamine agonist rotigotine on hemispatial neglect following stroke [PDF]

, 2012
Hemispatial neglect following right-hemisphere stroke is a common and disabling disorder, for which there is currently no effective pharmacological treatment. Dopamine agonists have been shown to play a role in selective attention and working memory, two
Kulinskaya, Elena, Singh-Curry, Victoria, Nair, Ajoy, Singh-Curry, V, Ward, N, Ward, Nick, Mah, Y-H, Mah, Yee-Haur, Greenwood, Richard, Cohen, D, Simister, R, Hadji-Michael, M, Greenwood, R, Cohen, David, Mah, YH, Machner, Bjoern, Husain, M, Malhotra, Paresh, Kulinskaya, E, Gorgoraptis, N, Gorgoraptis, Nikos, Machner, B, Malhotra, P, Nair, A, Hadji-Michael, Maria, Simister, Robert, Husain, Masud   +26 more
core   +1 more source

Prenatal Brain Damage in Preeclamptic Animal Model Induced by Gestational Nitric Oxide Synthase Inhibition

Journal of Pregnancy, 2011
Cerebral palsy is a major neonatal handicap with unknown aetiology. There is evidence that prenatal brain injury is the leading cause of CP. Severe placental pathology accounts for a high percentage of cases.
Begoña Pellicer, Sonia Herraiz, Antonio Leal, Carlos Simón, Antonio Pellicer   +4 more
doaj   +1 more source

The involvement of secondary neuronal damage in the development of neuropsychiatric disorders following brain insults

Frontiers in Neurology, 2014
Neuropsychiatric disorders are one of the leading causes of disability worldwide and affect the health of billions of people. Previous publications have demonstrated that neuropsychiatric disorders can cause histomorphological damage in particular ...
Yun eChen, Gregory eGarcia, Wei eHuang, Shlomi eConstantini   +3 more
doaj   +1 more source

Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons, Nuria Guillen, Jordi Sarto, Neus Falgàs, Sergi Borrego‐Écija, Diana Esteller‐Gauxax, Magda Castellví, Adrià Tort‐Merino, Agnès Pérez‐Millan, Anna Antonell, Josep M. Augè Fradera, Gerard Piñol, Iolanda Riba, Anna Carnes‐Vendrell, Marta Cullell, Maria Teresa Osuna, Lorena Bajo, Teresa Romero, Eva Bonjoch, Joan Bello, Susana Fernández, Marta Balagué, Isabel Gómez‐Ruiz, Anuncia Boltes, Claustre Pont, Raquel Cuevas, Sara Carrillo, Laura Iglesias, Teresa Maria Casadevall Codina, Lorena Grau Guinea, Fernando Jose Espada, Raquel Sánchez‐Valle, Mircea Balasa, Albert Lladó   +33 more
wiley   +1 more source