Results 71 to 80 of about 4,854,049 (293)

Fluoxetine restores spatial learning but not accelerated forgetting in mesial temporal lobe epilepsy

, 2012
Learning and memory dysfunction is the most common neuropsychological effect of mesial temporal lobe epilepsy, and because the underlying neurobiology is poorly understood, there are no pharmacological strategies to help restore memory function in these ...
Shtaya, Anan, Taylor, Matthew, Hamilton, Derek A., Gray, William Peter, Barkas, Lisa, Redhead, Edward, Gray, William P.   +6 more
core   +1 more source

Microglia Involvement into Acute and Chronic Brain Damage in Diabetic Rats: Impact of GLP-1RA and SGLT-2i

Frontiers in Bioscience-Landmark
Background: Acute and chronic brain damage in type 2 diabetes mellitus (DM) determines the need to investigate the neuroprotective potential of glucose-lowering drugs.
Anna Simanenkova, Oksana Fuks, Natalya Timkina, Alina Islamova, Dina Sufieva, Оlga Kirik, Dmitrii Korzhevskii, Timur Vlasov, Tatiana Karonova   +8 more
doaj   +1 more source

Roles of White Matter in Central Nervous System Pathophysiologies

ASN Neuro, 2012
The phylogenetic enlargement of cerebral cortex culminating in the human brain imposed greater communication needs that have been met by the massive expansion of WM (white matter).
Carlos Matute, Bruce R Ransom
doaj   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

Conventional Brain MRI in Carbon Monoxide Poisoning

Journal of Nepal Medical Association, 2015
Carbon monoxide poisoning is a common fatal condition which can have acute or chronic presentation with varying severity. It commonly involves globus pallidus and putamen but can involve other parts of brain.
Ashish Khanal, Subash Thapa, Pramod Kumar Chhetri   +2 more
doaj   +3 more sources

A self-insertable 5-μm-diameter flexible microneedle for minimally invasive and stable in vivo neural recording

Sensing and Bio-Sensing Research
Implantable intracortical microelectrodes are essential tools for neuroscience research, clinical applications, and brain–computer interfaces. Achieving stable chronic recording of neuronal activity, however, remains challenging due to tissue damage ...
Hinata Sasaki, Sayaki Shimizu, Rexy Alvian Nerchan, Koji Yamashita, Naohiro Takahashi, Rina Chinone, Yurika Kurashige, Rika Numano, Kowa Koida, Masahiro Ohsawa, Takeshi Kawano   +10 more
doaj   +1 more source

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen, Stéphane Jean, Weihong Liu, Yihai Dai, Xinrong Fang, Xiaoqiang Wei, Shan Chen, Shiwei Song   +7 more
wiley   +1 more source

Huanglian Jiedu decoction alleviates neurobehavioral damage in mice with chronic alcohol exposure through the RAS-RAF-MEK-ERK pathway

Heliyon
Objective: Long-term alcohol consumption can cause organic damage to the brain, resulting in mental and nervous system abnormalities and intellectual impairment.
Yun Chen, Lianyan Jiang, Mao Li, Yuling Shen, Shanyu Liu, Dongdong Yang   +5 more
doaj   +1 more source

An Assessment of Melatonin’s Therapeutic Value in the Hypoxic-Ischemic Encephalopathy of the Newborn

Frontiers in Synaptic Neuroscience, 2019
Hypoxic-ischemic encephalopathy (HIE) is one of the most frequent causes of brain injury in the newborn. From a pathophysiological standpoint, a complex process takes place at the cellular and tissue level during the development of newborn brain damage ...
Daniel P. Cardinali
doaj   +1 more source

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich, Jonathan A. Gernert, Hanna Zimmermann, Lisa Tagnin, Marianthi Zeinaki, Laura Sanzo, Letizia Vogler, Elisabeth Kaufmann, Justina Dargvainiene, Frank Leypoldt, Gérard N. Bischof, Robert Perneczky, Boris‐Stephan Rauchmann, Simon Lindner, Günter U. Höglinger, Rudolf A. Werner, Martin Kerschensteiner, Tania Kümpfel, Matthias Brendel, Franziska S. Thaler   +19 more
wiley   +1 more source