Results 51 to 60 of about 3,343,469 (285)

Globalization, brain drain and development [PDF]

open access: yes
This paper reviews four decades of economics research on the brain drain, with a focus on recent contributions and on development issues. We first assess the magnitude, intensity and determinants of the brain drain, showing that brain drain (or high ...
Frédéric DOCQUIER, Hillel RAPOPORT
core   +3 more sources

Epilepsy-linked kinase CDKL5 phosphorylates voltage-gated calcium channel Cav2.3, altering inactivation kinetics and neuronal excitability

open access: yesNature Communications, 2023
Developmental and epileptic encephalopathies (DEEs) are a group of rare childhood disorders characterized by severe epilepsy and cognitive deficits. Numerous DEE genes have been discovered thanks to advances in genomic diagnosis, yet putative molecular ...
Marisol Sampedro-Castañeda   +9 more
doaj   +1 more source

Imaging brain development: The adolescent brain

open access: yesNeuroImage, 2012
The past 15 years have seen a rapid expansion in the number of studies using neuroimaging techniques to investigate maturational changes in the human brain. In this paper, I review MRI studies on structural changes in the developing brain, and fMRI studies on functional changes in the social brain during adolescence.
openaire   +2 more sources

The Actin-binding Protein Moesin and Memory Formation in Drosophila : A thesis presented to Massey University in partial fulfillment of the requirements for the degree of Master of Science in Biochemistry [PDF]

open access: yes, 2016
Moesin is a cytoskeletal adaptor protein that plays an important role in modification of the actin cytoskeleton and the formation of dendritic spines, which may be crucial to long-term potentiation.
Freymuth, Patrick Stephen
core  

Monoamine oxidase A expression is vital for embryonic brain development by modulating developmental apoptosis [PDF]

open access: yes, 2011
Monoamine oxidases (MAO-A, MAO-B) metabolize biogenic amines and have been implicated in neuronal apoptosis. Although apoptosis is an important process in embryo development, the role of MAO isoenzymes has not been investigated in detail.
Alwan   +45 more
core   +1 more source

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee   +9 more
wiley   +1 more source

Enhancement of Vivid-based photo-activatable Gal4 transcription factor in mammalian cells

open access: yesCell Structure and Function, 2022
The Gal4/UAS system is a versatile tool to manipulate exogenous gene expression of cells spatially and temporally in many model organisms. Many variations of light-controllable Gal4/UAS system are now available, following the development of photo ...
Shinji C. Nagasaki   +6 more
doaj   +1 more source

Role of brain imaging in disorders of brain-gut interaction: a Rome Working Team Report. [PDF]

open access: yes, 2019
Imaging of the living human brain is a powerful tool to probe the interactions between brain, gut and microbiome in health and in disorders of brain-gut interactions, in particular IBS.
Aziz, Qasim   +8 more
core   +2 more sources

Feasibility and Safety of High‐Dose Proton Re‐Irradiation in Recurrent Pediatric Central Nervous System Tumors: A Single‐Institution Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song   +15 more
wiley   +1 more source

Longitudinal analysis of the developing rhesus monkey brain using magnetic resonance imaging: birth to adulthood. [PDF]

open access: yes, 2016
We have longitudinally assessed normative brain growth patterns in naturalistically reared Macaca mulatta monkeys. Postnatal to early adulthood brain development in two cohorts of rhesus monkeys was analyzed using magnetic resonance imaging.
Amaral, David G   +7 more
core   +1 more source

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