Results 201 to 210 of about 1,978,642 (301)

AMPA Receptors in Synaptic Plasticity, Memory Function, and Brain Diseases. [PDF]

Cell Mol Neurobiol
de León-López CAM, Carretero-Rey M, Khan ZU.   +2 more
europepmc   +1 more source

Pyogenic Brain Disease [PDF]

Annals of Otology, Rhinology & Laryngology, 1897
openaire   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Progress on the Mechanisms and Neuroprotective Benefits of Dexmedetomidine in Brain Diseases. [PDF]

Brain Behav
Tao Z, Li P, Zhao X.
europepmc   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Human cerebral organoids: Complex, versatile, and human-relevant models of neural development and brain diseases. [PDF]

Neural Regen Res
Coronel R, González-Sastre R, Mateos-Martínez P, Maeso L, Llorente-Beneyto E, Martín-Benito S, Costa Gagosian VS, Foti L, González-Caballero MC, López-Alonso V, Liste I.   +10 more
europepmc   +1 more source

TBK1‐Associated Primary Lateral Sclerosis Followed by Right Temporal Variant Frontotemporal Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We report a 58‐year‐old woman with a novel splice‐site variant in the TANK‐binding kinase 1 (TBK1:c.993–2A>C p.Ala332TyrfsTer39) who sequentially developed primary lateral sclerosis (PLS) followed by right temporal variant frontotemporal dementia (rtvFTD). Neuroimaging demonstrated right anterior temporal atrophy before cognitive symptoms, and
Tomoyasu Matsubara, Naoki Kihara, Satoko Miyatake, Koji Fujita, Konoka Tachibana, Ryosuke Miyamoto, Hiroki Yamazaki, Yusuke Osaki, Nazere Keyoumu, Yuki Kuwano, Nobutoshi Morimoto, Suzuran Saito, Eriko Koshimizu, Yoichi Otomi, Kenji Ishibashi, Masafumi Harada, Naomichi Matsumoto, Hiroyuki Morino, Yuishin Izumi   +18 more
wiley   +1 more source

Health-Related Behaviors and Risk of Common Age-Related Brain Diseases Across Severities of Genetic Risk. [PDF]

Neurology
Marini S, Kimball TN, Mayerhofer E, Tack RWP, Senff JR, Prapiadou S, Rivier CA, Duskin J, Kourkoulis C, Falcone GJ, Yechoor N, Tanzi RE, Rosand J, Singh S, Parodi L, Anderson CD.   +15 more
europepmc   +2 more sources

Drug Delivery Targeting Neuroinflammation to Treat Brain Diseases. [PDF]

Bioconjug Chem
Wang J, Jia R, Wan W, Han H, Wang G, Li Z, Li J.   +6 more
europepmc   +1 more source

Arteriosclerotic Brain Disease [PDF]

Journal of Neurology, Neurosurgery & Psychiatry, 1984
openaire   +1 more source