Results 211 to 220 of about 1,136,218 (264)
Some of the next articles are maybe not open access.
Schizophrenia as a Brain Disease
Archives of Neurology, 1993It is now widely accepted that schizophrenia is a brain disease, yet the pathophysiology of this illness is still obscure. In some ways, we are at the same point in understanding the symptoms of this illness that medicine was in understanding the symptoms of heart failure before the circulatory system was discovered.
openaire +4 more sources
Mitochondrial Diseases of the Brain
Free Radical Biology and Medicine, 2013Neurodegenerative disorders are debilitating diseases of the brain, characterized by behavioral, motor and cognitive impairments. Ample evidence underpins mitochondrial dysfunction as a central causal factor in the pathogenesis of neurodegenerative disorders including Parkinson's disease, Huntington's disease, Alzheimer's disease, Amyotrophic lateral ...
Rajnish K, Chaturvedi, M, Flint Beal
openaire +2 more sources
Molecular Neurobiology, 2001
Zinc is one of the most abundant transition metals in the brain. A substantial fraction (10-15%) of brain zinc is located inside presynaptic vesicles of certain glutamatergic terminals in a free or loosely bound state. This vesicle zinc is released with neuronal activity or depolarization, probably serving physiologic functions.
openaire +2 more sources
Zinc is one of the most abundant transition metals in the brain. A substantial fraction (10-15%) of brain zinc is located inside presynaptic vesicles of certain glutamatergic terminals in a free or loosely bound state. This vesicle zinc is released with neuronal activity or depolarization, probably serving physiologic functions.
openaire +2 more sources
Selenium and selenoproteins in the brain and brain diseases
Journal of Neurochemistry, 2003AbstractOver the past three decades, selenium has been intensively investigated as an antioxidant trace element. It is widely distributed throughout the body, but is particularly well maintained in the brain, even upon prolonged dietary selenium deficiency.
Jun, Chen, Marla J, Berry
openaire +2 more sources
Hormesis, the concept that low doses of potentially harmful stressors can elicit adaptive, beneficial effects, plays a significant role in brain health and aging. Neurohormesis refers to the adaptive response of neurons to mild stress, activating pathways that enhance cellular repair.
Vernise J T, Lim +4 more
openaire +2 more sources
Vernise J T, Lim +4 more
openaire +2 more sources
Evolution and Disease of the Brain
Perspectives in Biology and Medicine, 1958become fossilized, but some evidence can be obtained by making casts of the interior of the cranium. In this way it has been possible for T. Edinger (i) to follow the evolution of the brain of the horse. Most of the reconstruction, however, has been inferred from laborious study of the brains of surviving animals believed, for sufficient reasons, to be
openaire +2 more sources
Lung Disease and Brain Development
Neonatology, 2006With the technical progress made in fetal and neonatal intensive care, perinatal mortality has decreased by 25% over the last decade and has expanded the surviving premature population. Prematurity drastically changes the environment of the developing organism.
Hüppi, Petra Susan +2 more
openaire +4 more sources
Hirschsprung’s disease and the brain
Pediatric Surgery International, 2010A link between factors governing brain development and the development of the ENS is not surprising as both processes are largely controlled by the same or similar neural growth factors which are expressed at more or less in the same spatio-temporal time frame.
openaire +3 more sources
Brain ventricles as windows into brain development and disease
Neuron, 2022Dilation of the fluid-filled cerebral ventricles (ventriculomegaly) characterizes hydrocephalus and is frequently seen in autism and schizophrenia. Recent work suggests that the genomic study of congenital hydrocephalus may be unexpectedly fertile ground for revealing insights into neural stem cell regulation, human cerebrocortical development, and ...
Phan Q. Duy +8 more
openaire +2 more sources
Acta Neuropsychiatrica, 2002
Cytokines (e.g. various interleukins and subfamily members, tumor necrosis factors, interferons, chemokines and growth factors) act in the brain as immunoregulators and neuromodulators. Over a decade ago, the integrative article ‘Immunoregulators in the Nervous System’ (Neurosci Biobehav Rev1991; 15: 185–215) provided a comprehensive framework of ...
openaire +2 more sources
Cytokines (e.g. various interleukins and subfamily members, tumor necrosis factors, interferons, chemokines and growth factors) act in the brain as immunoregulators and neuromodulators. Over a decade ago, the integrative article ‘Immunoregulators in the Nervous System’ (Neurosci Biobehav Rev1991; 15: 185–215) provided a comprehensive framework of ...
openaire +2 more sources