Results 51 to 60 of about 268,974 (335)
Computational analysis reveals increased blood deposition following repeated mild traumatic brain injury. [PDF]
, 2012 Mild traumatic brain injury (mTBI) has become an increasing public health concern as subsequent injuries can exacerbate existing neuropathology and result in neurological deficits.
Bhanu, Bir +5 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction The kappa‐free light chain (κ‐FLC) index is known to be highly sensitive and specific for diagnosing multiple sclerosis (MS), while little is understood about lambda (λ)‐FLC. This study assessed the κ‐FLC and λ‐FLC indices in autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy.
Michael Levraut +11 more
wiley +1 more source
Attenuation of Focal Cerebral Ischemic Injury Following Post Ischemic Inhibition of Angiotensin Converting Enzyme (ACE) Activity in Normotensive Rat [PDF]
Central renin angiotensin system has an important role on the cerebral microcirculation and metabolism. Our previous work showed that inhibition of angiotensin converting enzyme (ACE) activity prior to induction of ischemia protected the brain from ...
دهقان, غلامعباس +1 more
core +1 more source
Post-ischaemic treatment with the cyclooxygenase-2 inhibitor nimesulide reduces blood-brain barrier disruption and leukocyte infiltration following transient focal cerebral ischaemia in rats [PDF]
, 2007 Several studies suggest that cyclooxygenase (COX)-2 plays a pivotal role in the progression of ischemic brain damage. In the present study, we investigated the effects of selective inhibition of COX-2 with nimesulide (12 mg/kg) and selective inhibition ...
Candelario-Jalil, Eduardo +4 more
core +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The cervical spinal cord (cSC) is highly relevant to clinical dysfunction in multiple sclerosis (MS) but remains understudied using quantitative magnetic resonance imaging (MRI). We assessed magnetization transfer ratio (MTR), a semi‐quantitative MRI measure sensitive to MS‐related tissue microstructural changes, in the cSC and its ...
Lisa Eunyoung Lee +26 more
wiley +1 more source
Scientific Reports, 2023 Acute ischemic stroke is a sudden neurological event caused by brain ischemia. Patients with large vessel occlusion are at high risk of developing significant cerebral edema, which can lead to rapid neurological decline.
Alexandre Guimarães de Almeida Barros +8 more
doaj +1 more source
Pathogenesis of Brain Edema and Investigation into Anti-Edema Drugs [PDF]
International Journal of Molecular Sciences, 2015 Brain edema is a potentially fatal pathological state that occurs after brain injuries such as stroke and head trauma. In the edematous brain, excess accumulation of extracellular fluid results in elevation of intracranial pressure, leading to impaired nerve function.
Shotaro Michinaga, Yutaka Koyama
openaire +3 more sources
Glial Fibrillary Acidic Protein Astrocytopathy Based on a Two‐Center Chinese Cohort Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Glial fibrillary acidic protein astrocytopathy (GFAP‐A) is a recently defined nosological form belonging to the class of autoimmune inflammatory disorders affecting the central nervous system (CNS). Here, we report the clinical and MRI characteristics, treatment, and prognosis of a GFAP‐A cohort from two centers in China.
Ti Wu +13 more
wiley +1 more source
miR-7-5p Affects Brain Edema After Intracerebral Hemorrhage and Its Possible Mechanism
Frontiers in Cell and Developmental Biology, 2020 Objective: To explore the relationship between miR-7-5p and brain edema after intracerebral hemorrhage and the role of butylphthalide (NBP) in brain edema after intracerebral hemorrhage.Method: Routine blood testing, C-reactive protein results, and ...
Xiqian Chen +7 more
doaj +1 more source
EDEMA OF THE BRAIN IN THE INFECTIOUS DISEASES [PDF]
Journal of the American Medical Association, 1919 Little is to be found in the literature relative to edema of the brain in the infectious diseases as a clinical entity, and much less, therefore, if anything, as to edema as a clinical type of an infectious disease. We are all familiar with the occurrence of meningismus in acute diseases, and during the febrile stage are not surprised to have some ...
openaire +3 more sources