Results 11 to 20 of about 276,027 (337)
Veterinary Pathology, 2002 Animal models have played a critical role in elucidating the complex pathogenesis of traumatic brain injury, the major cause of death and disability in young adults in Western countries. This review discusses how different types of animal models are useful for the study of neuropathologic processes in traumatic, blunt, nonmissile head injury.
Finnie, J., Blumbergs, P.
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CNS Neuroscience & Therapeutics, 2020 A head trauma is any injury that results in trauma to the skull, scalp, or brain. Every patient with a suspected head trauma should initially undergo a focused neurological examination which consists of the Glasgow Coma Scale Score (GCS), plus pupillary reactivity, that classifies the traumatic brain injury (TBI) as mild, moderate, or severe.
Julian E. Bailes, Cesar V. Borlongan
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Journal of Anesthesia and Anesthetic Drugs, 2022 The risk of developing an addiction to alcohol, tobacco, or drugs increases in the period immediately following mild traumatic brain injury (mTBI) but decreases over time, new research shows. The historical prospective study showed that in the short-term, individuals with mTBI had a significantly increased risk for alcohol dependence, nicotine ...
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Rehabilitation Research and Practice, 2012 Mild traumatic brain injury (mTBI), commonly known as concussion, is one of the most common neurologic disorders [1]. Based on emergency room visits, hospitalizations, and deaths, an estimated 1.7 million people sustain a traumatic brain injury (TBI) annually in the United States [2]. About 80% of TBIs that occur each year are mild TBI [3].
Anne Felicia Ambrose +2 more
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Traumatic brain injuries [PDF]
Nature Reviews Disease Primers, 2016 Traumatic brain injuries (TBIs) are clinically grouped by severity: mild, moderate and severe. Mild TBI (the least severe form) is synonymous with concussion and is typically caused by blunt non-penetrating head trauma. The trauma causes stretching and tearing of axons, which leads to diffuse axonal injury - the best-studied pathogenetic mechanism of ...
Gerard M. Ribbers +9 more
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Astrocytes and Brain Injury [PDF]
Journal of Cerebral Blood Flow & Metabolism, 2003 Astrocytes are the most numerous cell type in the central nervous system. They provide structural, trophic, and metabolic support to neurons and modulate synaptic activity. Accordingly, impairment in these astrocyte functions during brain ischemia and other insults can critically influence neuron survival.
Yongmei Chen, Raymond A. Swanson
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Data-driven decomposition of brain dynamics with principal component analysis in different types of head impacts [PDF]
, 2021 Strain and strain rate are effective traumatic brain injury predictors. Kinematics-based models estimating these metrics suffer from significant different distributions of both kinematics and the injury metrics across head impact types. To address this, previous studies focus on the kinematics but not the injury metrics.
arxiv +1 more source