Results 21 to 30 of about 685,589 (294)
Frontiers in Physiology, 2012 We recently reported that the neuropathic pain medication, gabapentin (GBP; Neurontin), significantly attenuated both noxious colorectal distension (CRD)-induced autonomic dysreflexia (AD) and tail pinch-induced spasticity compared to saline-treated ...
Alexander G. Rabchevsky +12 more
doaj +1 more source
Acute inflammatory profiles differ with sex and age after spinal cord injury
Journal of Neuroinflammation, 2021 Background Sex and age are emerging as influential variables that affect spinal cord injury (SCI) recovery. Despite a changing demographic towards older age at the time of SCI, the effects of sex or age on inflammation remain to be elucidated. This study
Andrew N. Stewart +8 more
doaj +1 more source
Genetic Approach to Elucidate the Role of Cyclophilin D in Traumatic Brain Injury Pathology
Cells, 2021 Cyclophilin D (CypD) has been shown to play a critical role in mitochondrial permeability transition pore (mPTP) opening and the subsequent cell death cascade.
Ryan D. Readnower +4 more
doaj +1 more source
Evidence of the role of the cerebellum in cognitive theory of mind using voxel-based lesion mapping
Scientific Reports, 2022 Theory of Mind (ToM) is a social-cognitive skill that allows the understanding of the intentions, beliefs, and desires of others. There is a distinction between affective and cognitive ToM, with evidence showing that these processes rely on partially ...
Pierre-Aurélien Beuriat +5 more
doaj +1 more source
Trials, 2017 Background An acquired brain injury (ABI) is a complex injury often followed by a broad range of cognitive, physical, emotional, and behavioral disabilities. Because of these disabilities, vocational rehabilitation (VR) is a challenging task, however, of
Louise K. Hoeffding +8 more
doaj +1 more source
Sedation-Induced Burst Suppression Predicts Positive Outcome Following Traumatic Brain Injury
Frontiers in Neurology, 2021 While electroencephalogram (EEG) burst-suppression is often induced therapeutically using sedatives in the intensive care unit (ICU), there is hitherto no evidence with respect to its association to outcome in moderate-to-severe neurological patients. We
Joel Frohlich +11 more
doaj +1 more source
Journal of Neurosurgery, 2016 OBJECT Helmets are used for sports, military, and transportation to protect against impact forces and associated injuries. The common belief among end users is that the helmet protects the whole head, including the brain. However, current consensus among biomechanists and sports neurologists indicates that helmets do not provide significant protection
Frank Conidi, John D Lloyd
openaire +3 more sources
Apolipoprotein E4 impairs spontaneous blood brain barrier repair following traumatic brain injury
Molecular Neurodegeneration, 2018 Background Traumatic Brain Injury (TBI) is a major cause of disability and mortality, to which there is currently no comprehensive treatment. Blood Brain Barrier (BBB) dysfunction is well documented in human TBI patients, yet the molecular mechanisms ...
Bevan S. Main +10 more
doaj +1 more source
Scientific Reports, 2023 Traumatic brain injury (TBI) affects how the brain functions in the short and long term. Resulting patient outcomes across physical, cognitive, and psychological domains are complex and often difficult to predict.
Andrew Tritt +9 more
doaj +1 more source