Cell Reports, 2020 Summary: Brain CD11c+ cells share features with microglia and dendritic cells (DCs). Sterile inflammation increases brain CD11c+ cells, but their phenotype, origin, and functions remain largely unknown.
Mattia Gallizioli +16 more
doaj
Hypothermia selectively protects the anterior forebrain mesocircuit during global cerebral ischemia
Neural Regeneration Research, 2022 Hypothermia is an important protective strategy against global cerebral ischemia following cardiac arrest. However, the mechanisms of hypothermia underlying the changes in different regions and connections of the brain have not been fully elucidated ...
Xiao-Hua Wang +7 more
doaj +1 more source
Non-invasive Deep-Brain Imaging with 3D Integrated Photoacoustic Tomography and Ultrasound Localization Microscopy (3D-PAULM) [PDF]
arXiv, 2023 Photoacoustic computed tomography (PACT) is a proven technology for imaging hemodynamics in deep brain of small animal models. PACT is inherently compatible with ultrasound (US) imaging, providing complementary contrast mechanisms. While PACT can quantify the brain's oxygen saturation of hemoglobin (sO$_2$), US imaging can probe the blood flow based on
arxiv
APIS: A paired CT-MRI dataset for ischemic stroke segmentation challenge [PDF]
, 2023 Stroke is the second leading cause of mortality worldwide. Immediate attention and diagnosis play a crucial role regarding patient prognosis. The key to diagnosis consists in localizing and delineating brain lesions. Standard stroke examination protocols include the initial evaluation from a non-contrast CT scan to discriminate between hemorrhage and ...
arxiv +1 more source
Brain tissue responses to ischemia [PDF]
Journal of Clinical Investigation, 2000 The brain is particularly vulnerable to ischemia. Complete interruption of blood flow to the brain for only 5 minutes triggers the death of vulnerable neurons in several brain regions, whereas 20–40 minutes of ischemia is required to kill cardiac myocytes or kidney cells.
Gregory J. Zipfel +3 more
openaire +3 more sources
Enlarged infarct volume and loss of BDNF mRNA induction following brain ischemia in mice lacking FGF-2 [PDF]
, 2006 FGF-2, a potent multifunctional and neurotrophic growth factor, is widely expressed in the brain and upregulated in cerebral ischemia. Previous studies have shown that intraventricularly or systemically administered FGF-2 reduces the size of cerebral ...
Bohlen und Halbach, Oliver von +6 more
core
Emergency decompressive craniectomy after removal of convexity meningiomas [PDF]
, 2016 BACKGROUND: Convexity meningiomas are benign brain tumors that are amenable to complete surgical resection and are associated with a low complication rate.
D'Elia, Alessandro +8 more
core +2 more sources
RatLesNetv2: A Fully Convolutional Network for Rodent Brain Lesion Segmentation [PDF]
, 2020 We present a fully convolutional neural network (ConvNet), named RatLesNetv2, for segmenting lesions in rodent magnetic resonance (MR) brain images. RatLesNetv2 architecture resembles an autoencoder and it incorporates residual blocks that facilitate its optimization.
arxiv +1 more source
MicroRNA responses to focal cerebral ischemia in male and female mouse brain
Frontiers in Molecular Neuroscience, 2014 Stroke occurs with greater frequency in men than in women across diverse ethnic backgrounds and nationalities. Work from our lab and others have revealed a sex-specific sensitivity to cerebral ischemia whereby males exhibit a larger extent of brain ...
Theresa Ann Lusardi +7 more
doaj +1 more source
Ischemic neurons recruit natural killer cells that accelerate brain infarction [PDF]
, 2014 Brain ischemia and reperfusion activate the immune system. The abrupt development of brain ischemic lesions suggests that innate immune cells may shape the outcome of stroke.
A. La Cava +38 more
core +1 more source