Results 71 to 80 of about 2,529,991 (308)

Disruption of the Serotonergic System after Neonatal Hypoxia-Ischemia in a Rodent Model

Neurology Research International, 2012
Identifying which specific neuronal phenotypes are vulnerable to neonatal hypoxia-ischemia, where in the brain they are damaged, and the mechanisms that produce neuronal losses are critical to determine the anatomical substrates responsible for ...
Kathryn M. Buller, Julie A. Wixey, Hanna E. Reinebrant   +2 more
doaj   +1 more source

Protective effects of Echium amoenum Fisch. and C.A. Mey. against cerebral ischemia in the rats

Advanced Biomedical Research, 2015
Background: This study was designed to evaluate the protective effect of Echium amoenum total anthocyanin extract (ETAE) on partial/transient cerebral ischemia in the rats.
Leila Safaeian, Abolfazl Azami Tameh, Alireza Ghannadi, Elmira Akbari Naghani, Hamed Tavazoei, Samaneh Sadat Alavi   +5 more
doaj   +1 more source

Mechanisms Underlying Curcumin-Induced Neuroprotection in Cerebral Ischemia

Frontiers in Pharmacology, 2022
Ischemic stroke is the leading cause of death and disability worldwide, and restoring the blood flow to ischemic brain tissues is currently the main therapeutic strategy.
Feng Fan, Meng Lei
doaj   +1 more source

SARS‐CoV‐2 Is Linked to Brain Volume Loss in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The impact of SARS‐CoV‐2 infection on brain and spinal cord pathology in patients with multiple sclerosis (pwMS) remains unclear. We aimed to describe changes in brain lesion activity and brain and spinal cord volumes following SARS‐CoV‐2 infection.
Tomas Uher, Dominika Stastna, Ingrid Menkyova, Vaclav Capek, Jiri Lindner, Petra Nytrova, Jan Krasensky, Eliza Varju, Miguel D'haeseleer, Eva Kubala Havrdova, Dana Horakova, Manuela Vaneckova, Niels Bergsland   +12 more
wiley   +1 more source

Time course of oxidative damage in different brain regions following transient cerebral ischemia in gerbils [PDF]

, 2001
The time course of oxidative damage in different brain regions was investigated in the gerbil model of transient cerebral ischemia. Animals were subjected to both common carotid arteries occlusion for 5 min.
Al-Dalain, Saied M., Candelario-Jalil, Eduardo, Leon, Olga S., Martinez, Gregorio, Mhadu, Noel H.   +4 more
core  

Dysregulation of Amyloid-β Protein Precursor, β-Secretase, Presenilin 1 and 2 Genes in the Rat Selectively Vulnerable CA1 Subfield of Hippocampus Following Transient Global Brain Ischemia

Journal of Alzheimer's Disease, 2015
The interaction between brain ischemia and Alzheimer’s disease (AD) has been intensively investigated recently. Nevertheless, we have not yet understood the nature and mechanisms of the ischemic episodes triggering the onset of AD and how they influence ...
J. Kocki, Marzena Ułamek-Kozioł, A. Bogucka-Kocka, S. Januszewski, M. Jabłoński, Paulina Gil-Kulik, J. Brzozowska, Alicja Petniak, W. Furmaga-Jabłońska, J. Bogucki, S. Czuczwar, R. Pluta   +11 more
semanticscholar   +1 more source

To the problems of modeling the brain ischemia in small animals

Journal of Education, Health and Sport, 2019
In the review article the problems of modeling cerebral ischemia in small mammals are consecrated. The advantages of experimental studies that are based on the similarity of the blood circulation of the brain in humans and animals are indicated ...
A. N. Stoyanov, S. S. Mashchenko, I. O. Ostapenko, I. K. Bakumenko, S. M. Oleinik, V. Z. Skorobreha   +5 more
doaj   +3 more sources

Intravenous tPA therapy does not worsen acute intracerebral hemorrhage in mice [PDF]

, 2013
Tissue plasminogen activator (tPA) is the only FDA-approved treatment for reperfusing ischemic strokes. But widespread use of tPA is still limited by fears of inadvertently administering tPA in patients with intracerebral hemorrhage (ICH).
Arai, Ken, Cianchetti, Flor A., Fan, Xiang, Förch, Christian, Lauer, Arne, Leyen, Klaus van, Lo, Eng H., Mandeville, Emiri, Rosidi, Nathanael L., Schaffer, Chris B., Schlunk, Frieder, Steinmetz, Helmuth, Wang, Xiaoying, Yigitkanli, Kazim   +13 more
core   +7 more sources

An investigation of postmortem urotensin II receptor levels in brain and kidney tissues in a rat model of cardiac ischemia

Journal of Forensic Science and Medicine, 2018
This study aimed to investigate changes in postmortem urotensin II receptor (UTR) levels in brain and kidney tissues in a rat model of cardiac ischemia. The rats were divided into two groups: a control group and a cardiac ischemia-induced group.
Mustafa Talip Sener, Erol Akpinar, Elif Cadirci, Zekai Halici, Irfan Cinar, Ahmet Nezih Kok   +5 more
doaj   +1 more source

Muscle activity and emotional behavior changes in rats with chronic brain ischemia via comprehensive pathogenetic correction

Journal of Education, Health and Sport, 2023
Cerebrovascular pathology has evolved from a medical concern to a social issue, with the efficacy of secondary neuroprotection remaining a pertinent question.
V. Kirchev
doaj   +1 more source