Results 11 to 20 of about 3,164,098 (302)
Association of the fibronectin type III domain–containing protein 5 rs1746661 single nucleotide polymorphism with reduced brain glucose metabolism in elderly humans [PDF]
, 2023 Lima-Filho et al. reported that cognitively unimpaired elders carrying the FNDC5 rs1746661(T) allele develop low brain glucose metabolism and increased amyloid deposition.
Andréa L Benedet +19 more
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Metabolism and Brain Cancer [PDF]
Clinics, 2011 Cellular energy metabolism is one of the main processes affected during the transition from normal to cancer cells, and it is a crucial determinant of cell proliferation or cell death. As a support for rapid proliferation, cancer cells choose to use glycolysis even in the presence of oxygen (Warburg effect) to fuel macromolecules for the synthesis of ...
Marie, Suely Kazue Nagahashi +1 more
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A model of brain circulation and metabolism: NIRS signal changes during physiological challenges [PDF]
, 2008 We construct a model of brain circulation and energy metabolism. The model is designed to explain experimental data and predict the response of the circulation and metabolism to a variety of stimuli, in particular, changes in arterial blood pressure, CO2
Mallet, Alfred +18 more
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Association between cognitive performance and cortical glucose metabolism in patients with mild Alzheimer's disease [PDF]
, 2005 Background: Neuronal and synaptic function in Alzheimer's disease (AD) is measured in vivo by glucose metabolism using positron emission tomography (PET). Objective: We hypothesized that neuronal activation as measured by PET is a more sensitive index of
Teipel, S. J. +12 more
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Phosphorus Metabolism in Brain
Nutrition Reviews, 2009 Abstract The metabolism of the brain in vivo has been studied by measuring the rate of uptake of radioactive phosphorus into the different phosphorus-containing fractions of the mouse brain. By the use of specific-activity ratios referred to the acid-soluble fraction of the brain, satisfactorily constant values were obtained for the ...
R M C, DAWSON, D, RICHTER
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Brain endothelial miR-146a negatively modulates T-cell adhesion through repressing multiple targets to inhibit NF-κB activation. [PDF]
, 2014 Pro-inflammatory cytokine-induced activation of nuclear factor, NF-κB has an important role in leukocyte adhesion to, and subsequent migration across, brain endothelial cells (BECs), which is crucial for the development of neuroinflammatory disorders ...
Susanne MA van der Pol +52 more
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Human brain glycogen content and metabolism: Implications on its role in brain energy metabolism [PDF]
, 2007 The adult brain relies on glucose for its energy needs and stores it in the form of glycogen, primarily in astrocytes. Animal and culture studies indicate that brain glycogen may support neuronal function when the glucose supply from the blood is ...
Gruetter, R. +8 more
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Metabolic Recruitment in Brain Tissue
Annual Review of Physiology, 2023 Information processing imposes urgent metabolic demands on neurons, which have negligible energy stores and restricted access to fuel. Here, we discuss metabolic recruitment, the tissue-level phenomenon whereby active neurons harvest resources from their surroundings. The primary event is the neuronal release of K+that mirrors workload.
Barros, Luis Felipe +4 more
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Allometry of brain metabolism [PDF]
Proceedings of the National Academy of Sciences, 2013 Allometry refers to biological scaling relationships (1). With regard to metabolic rate, the earliest allometric studies demonstrated a complex inverse relationship between body size and resting metabolic rate (2⇓–4). Subsequent studies have focused, without much success, on describing the cellular mechanisms of this relationship.
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