Results 81 to 90 of about 1,871,454 (260)
, 2018 a. Total volume of brain metastases (mm3) of rats injected with MPIO-labeled (n = 13) or unlabeled (n = 8) cancer cells; data acquired 3 and 4 weeks post-injection. b.
Pieter Mollet (6065858) +10 more
core +1 more source
Advanced Functional Materials, EarlyView.Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou +6 more
wiley +1 more source
Advances in Bevacizumab Therapy for Non-small Cell Lung Cancer with Brain Metastases
Chinese Journal of Lung Cancer, 2016 Brain metastases are frequently encountered in patients with non-small cell lung cancer (NSCLC) and are a significant cause of morbidity and mortality.
Liyan QU, Rui GENG, Xia SONG
doaj +1 more source
Brain metastases in patients with low-grade endometrial carcinoma
Gynecologic Oncology Reports, 2018 Objective: To report characteristics of patients with low-grade endometrioid endometrial carcinoma (EC) who develop brain metastases. Methods: We retrospectively identified all patients treated at our institution for FIGO grades 1/2 EC from 1/2000–12 ...
Paulina Cybulska +8 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Biologically derived and hybrid nonviral nanovectors are examined as distinct but convergent design approaches. Integrating synthetic components with biologically functionalized membranes allows efficient interactions with complex cellular environments.
Clara Baldari +10 more
wiley +1 more source
Genetic Characterization of Brain Metastases in the Era of Targeted Therapy
Frontiers in Oncology, 2017 In the current era of molecularly targeted therapies and precision medicine, choice of cancer treatment has been increasingly tailored according to the molecular or genomic characterization of the cancer the individual has.
Catherine H. Han +2 more
doaj +1 more source
Brain metastases from renal cell carcinoma
, 2015 Brain metastasis is a major cause of morbidity and mortality in renal cancer patients. Treatment of metastatic renal cancer is difficult because most of RCCs are resistant to several therapeutic strategies: main studies support surgery as a therapeutic ...
FRATI, ALESSANDRO +3 more
core
Brain metastases: an overview [PDF]
, 2015 So far brain metastases represent a critical stage of a disease course and the frequency is increasing over the years. The treatment of brain metastases should be individualized for each patient: in case of single brain metastasis, surgery or ...
Spallanzani, A. +4 more
core +1 more source
Advanced Materials for Biologics Delivery to Brain Tumors
Advanced Materials, EarlyView.Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng +4 more
wiley +1 more source
Advanced Materials, EarlyView.A cholesterol‐conjugated lipid library enabled the identification of a ligand‐free LNP platform for efficient mRNA delivery to brain endothelial cells via systemic administration. This platform achieves selective BBB targeting without disrupting barrier integrity, and enables modulation of neuroinflammation and vascular function without requiring trans‐
Zeru Tian +7 more
wiley +1 more source