Results 61 to 70 of about 1,871,454 (260)

Ex-vivo HRMAS of adult brain tumours: metabolite quantification and assignment of tumour biomarkers [PDF]

, 2010
Background: High-resolution magic angle spinning (HRMAS) NMR spectroscopy allows detailed metabolic analysis of whole biopsy samples for investigating tumour biology and tumour classification.
B Bell, Griffiths, John R, Griffiths John R, Fellows, G.A., Wilson, M, Bell, B Anthony, Wright, Alan J, Wilson M, Fellows, Greg A, Howe, F.A., Bell, B.A., John R Griffiths, Wright, AJ, Wright Alan J, Fellows Greg A, Bell, BA, Bell B, Franklyn A Howe, Alan J Wright, Griffiths, JR, Greg A Fellows, Wright, A.J., Wilson, Martin; id_orcid, Griffiths, J.R., Wilson, M., Fellows, GA, Howe, FA, Howe Franklyn A, Howe, Franklyn A, M Wilson   +29 more
core   +2 more sources

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Clinical presentation of brain metastases from endometrial carcinoma: A case series

Gynecologic Oncology Reports, 2019
Brain metastases from endometrial carcinoma are rare, however they do occur, and they are associated with an especially poor prognosis. There is evidence demonstrating improved outcomes with early diagnosis and subsequent multimodal treatment. This study
Marisa R. Moroney, Lindsay J. Wheeler, Bradley R. Corr   +2 more
doaj   +1 more source

Total-liver-volume perfusion CT using 3-D image fusion to improve detection and characterization of liver metastases [PDF]

, 2008
The purpose of this study was to evaluate the feasibility of a totalliver- volume perfusion CT (CTP) technique for the detection and characterization of livermetastases.
Cornelis van Kuijk, van Waesberghe, Jan, Meijer, Sybren, Weide, Lineke van der, Sybren Meijer, van Kuijk, C., van den Tol, Petrousjka, Lineke van der Weide, van den Tol, M.P., van der Weide, L., Meijer, S., van der Weide, Lineke, Meijerink, Martijn, Martijn R. Meijerink, Jan Hein T. M. van Waesberghe, Meijerink, M.R., van Waesberghe, J.H.T.M., Kuijk, Cornelis van, Petrousjka van den Tol, Waesberghe, Jan van, Tol, Petrousjka van den   +20 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Predicting local control of brain metastases after stereotactic radiotherapy with clinical, radiomics and deep learning features

This data package contains the information needed to replicate the research titled - 'Predicting local control of brain metastases after stereotactic radiotherapy with clinical, radiomics and deep learning ...
Kanakarajan, Hemalatha, Sitskoorn, Margriet, De Baene, Wouter, Hanssens, Patrick   +3 more
core   +1 more source

Systemic treatment of non-small cell lung cancer brain metastases

, 2016
In the systemic treatment of brain metastases from non-small cell lung cancer (BMF-NSCLC) chemo- and targeted therapy are used. Response rates after platinum-based chemotherapy, range from 23% to 45%.
Maksymilian A. Kruczała, Tomasz Walasek, Ida Cedrych, Jerzy Jakubowicz, Paweł Blecharz, Marian Reinfuss   +5 more
core   +1 more source

Methods and results of locoregional treatment of brain metastases in patients with non-small cell lung cancer [PDF]

, 2016
This article presents methods and results of surgery and radiotherapy of brain metastases from non-small cell lung cancer (BMF-NSCLC). Patients with single BMF-NSCLC, with Karnofsky score ≥ 70 and controlled extracranial disease are the best candidates ...
Anna Patla, Walasek, Tomasz, Blecharz, Paweł, Jerzy Jakubowicz, Marian Reinfuss, Patla, Anna, Anna Mucha-Małecka, Jakubowicz, Jerzy, Tomasz Walasek, Mituś, Jerzy, Reinfuss, Marian, Paweł Blecharz, Jerzy Władysław Mituś, Mucha-Małecka, Anna   +13 more
core   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Revised guideline 'Brain metastases': More treatment options [PDF]

, 2020
The guideline on brain metastasis from the Netherlands Society of Neurology has been updated. Important changes have been made, particularly with regard to treatment of brain metastases. Treatment of patients with brain metastases is complex and requires
Gijtenbeek, J M M, Lagerwaard, Frank J, Hilkens, Nina A, Enting, Roelien H, de Vos, Filip Y F L, Hendriks, Lizza E L   +5 more
core   +5 more sources