Results 51 to 60 of about 1,871,454 (260)

Cystic brain metastases had slower speed of tumor shrinkage but similar prognosis compared with solid tumors that underwent radiosurgery treatment

Cancer Management and Research, 2019
Hui Wang,* Xiaoye Liu,* Xuechao Jiang, Yongchun Song, Xiaoguang Wang, Jingsheng Wang, Yang Dong, Fengtong Li, Zhiqiang Wu, Yuhan Zhang, Zhiyong Yuan Department of Radiation Oncology, Tianjin Medical University Cancer Institute and Hospital, National ...
Wang H, Liu X, Jiang X, Song Y, Wang X, Wang J, Dong Y, Li F, Wu Z, Zhang Y, Yuan Z   +10 more
doaj  

O-6-Methylguanine-DNA Methyltransferase Expression and Prognostic Value in Brain Metastases of Lung Cancers

, 2011
O(6)-Methylguanine-DNA methyltransferase (MGMT) is critical for repairing pro-mutagenic DNA bases and is correlated with response to alkylating agents in cancers.
吳佩芳;郭冠廷;郭律廷;林怡婷;盧彥伸;楊志新;吳瑞美;杜永光;蔡瑞章;曾漢民;曾勝弘;鄭安理;林璟宏, WU, PEI-FANG;KUO, KUAN-TING;KUO, LU-TING;LIN, YI-TING;LU, YEN-SHEN;YANG, CHIH-HSIN;WU, RUEY-MEEI;TU, YONG-KWANG;TSAI, JUI-CHANG;TSENG, HAN-MIN;TSENG, SHENG-HONG;CHENG, ANN-LII;LIN, CHING-HUNG   +1 more
core   +1 more source

Music and the brain: disorders of musical listening [PDF]

, 2006
The study of the brain bases for normal musical listening has advanced greatly in the last 30 years. The evidence from basic and clinical neuroscience suggests that listening to music involves many cognitive components with distinct brain substrates ...
Stewart, Lauren, Griffiths, Timothy D., Warren, J., Lauren Stewart, Von Kriegstein, K., Stewart, L., Katharina Von Kriegstein, Timothy D. Griffiths, Griffiths, T., Warren, Jason D., Jason D. Warren, JD, Warren, TD, Griffiths, von Kriegstein, K, Stewart, L; id_orcid   +14 more
core   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Extrathoracic Metastases in Pleural Mesothelioma

JTO Clinical and Research Reports, 2023
Introduction: Guidelines recommend obtaining a computed tomography scan of the chest for the staging of pleural mesothelioma and for assessing response to treatment.
Ibiayi Dagogo-Jack, MD, Beow Y. Yeap, ScD, Mari Mino-Kenudson, MD, Subba R. Digumarthy, MD   +3 more
doaj   +1 more source

White matter damage and cognitive impairment after traumatic brain injury [PDF]

, 2010
White matter disruption is an important determinant of cognitive impairment after brain injury, but conventional neuroimaging underestimates its extent.
Powell, Jane Hilary, Leech, R, K. M. Kinnunen, Counsell, Serena Jane; id_orcid, Bonnelle, V., Bonnelle, V, Sharp, D. J., Kinnunen, K. M., Hawkins, Peter Charlie; id_orcid, Patel, Maneesh Chandrakant, Patel, MC, M. C. Patel, Sharp, David James, Greenwood, Richard, D. J. Sharp, Hawkins, PC, Leech, R., Patel, M. C., Powell, Jane H., Greenwood, R, J. H. Powell, Counsell, S. J., Sharp, DJ, P. C. Hawkins, Counsell, SJ, Powell, JH, R. Greenwood, Kinnunen, KM, R. Leech, Bonnelle, Valerie, Leech, Robert, V. Bonnelle, Kinnunen, Kirsi Maria, Hawkins, R. C., S. J. Counsell   +34 more
core   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Therapy of breast cancer brain metastases: challenges, emerging treatments and perspectives

Therapeutic Advances in Medical Oncology, 2018
Brain metastases are the most common central nervous system tumors in adults, and incidence of brain metastases is increasing due to both improved diagnostic techniques (e.g.
Nuria Kotecki, Florence Lefranc, Daniel Devriendt, Ahmad Awada   +3 more
doaj   +1 more source

Alterations of functional and structural connectivity in patients with brain metastases.

PLoS ONE, 2020
Metastases are the most prevalent tumors in the brain and are commonly associated with high morbidity and mortality. Previous studies have suggested that brain tumors can induce a loss of functional connectivity and alter the brain network architecture ...
Bo Hua, Xin Ding, Minghua Xiong, Fanyu Zhang, Yi Luo, Jurong Ding, Zhongxiang Ding   +6 more
doaj   +1 more source

Effect of whole-brain radiotherapy with platinum-based chemotherapy in non-small cell lung cancer patients with multiple metastases including brain metastases

Scientific Reports, 2023
Current guidelines recommend that cytotoxic chemotherapy be considered first in non-small cell lung cancer (NSCLC) patients with multiple metastases, and whole-brain radiotherapy (WBRT) is not initially recommended even if brain metastases are present ...
Woo Kyung Ryu, Hyung Keun Cha, Woochul Kim, Ha Young Lee, Hyun-Jung Kim, Jeong-Seon Ryu, Jun Hyeok Lim   +6 more
doaj   +1 more source