Results 51 to 60 of about 2,926,291 (344)

Immune suppressive microenvironment in brain metastatic non-small cell lung cancer: comprehensive immune microenvironment profiling of brain metastases versus paired primary lung tumors (GASTO 1060)

OncoImmunology, 2022
Lung cancer is one of the most common causes of brain metastases and is always associated with poor prognosis. We investigated the immunophenotypes of primary lung tumors and paired brain metastases, as well as immunophenotypes in the synchronous group ...
Meichen Li, Xue Hou, Ke Sai, Lihong Wu, Jing Chen, Baishen Zhang, Na Wang, Lijia Wu, Hongbo Zheng, Jiao Zhang, Yonggao Mou, Likun Chen   +11 more
doaj   +1 more source

Effect of Radiosurgery Alone vs Radiosurgery With Whole Brain Radiation Therapy on Cognitive Function in Patients With 1 to 3 Brain Metastases

Journal of the American Medical Association (JAMA), 2016
IMPORTANCE Whole brain radiotherapy (WBRT) significantly improves tumor control in the brain after stereotactic radiosurgery (SRS), yet because of its association with cognitive decline, its role in the treatment of patients with brain metastases remains
P. Brown, K. Jaeckle, K. Ballman, E. Farace, J. Cerhan, S. K. Anderson, X. Carrero, F. Barker, R. Deming, S. Burri, Cynthia Ménard, Cynthia Ménard, C. Chung, V. Stieber, B. Pollock, E. Galanis, J. Buckner, A. Asher   +17 more
semanticscholar   +1 more source

Brain Metastases from Colorectal Cancer: A Systematic Review of the Literature and Meta-Analysis to Establish a Guideline for Daily Treatment

Cancers, 2021
Simple Summary Brain metastases (BM) from colorectal cancer (CRC) are rare. There is little available information regarding incidence, risk factors, prognostic factors, treatment, and overall survival (OS).
Sophie Müller, F. Köhler, Anne Hendricks, C. Kastner, Kevin Börner, J. Diers, J. Lock, B. Petritsch, C. Germer, A. Wiegering   +9 more
semanticscholar   +1 more source

Brain malignancies: Glioblastoma and brain metastases

Seminars in Cancer Biology, 2020
Brain, the major organ of the central nervous system controls and processes most of body activities. Therefore, the most aggressive brain tumor - glioblastoma and metastases from other organs to the brain are lethal leaving the patients with very short time of survival.
Lah Turnšek, Tamara, Novak, Metka, biokemija, Breznik, Barbara   +2 more
openaire   +3 more sources

Revisiting Indications for Brain Imaging During the Clinical Staging Evaluation of Lung Cancer

JTO Clinical and Research Reports, 2022
Introduction: Available guidelines are inconsistent as to whether patients with newly diagnosed clinical stage II NSCLC should receive routine brain imaging.
Matthew D. Pichert, MD, Maureen E. Canavan, PhD, MPH, Richard C. Maduka, MD, Andrew X. Li, MD, Theresa Ermer, MD, Peter L. Zhan, MD, Michael Kaminski, BA, Brooks V. Udelsman, MD, MHS, Justin D. Blasberg, MD, MPH, Vincent J. Mase, Jr., MD, Andrew P. Dhanasopon, MD, Daniel J. Boffa, MD, MBA   +11 more
doaj   +1 more source

Dynamic contrast‐enhanced MRI perfusion for differentiating between melanoma and lung cancer brain metastases

Cancer Medicine, 2017
Brain metastases originating from different primary sites overlap in appearance and are difficult to differentiate with conventional MRI. Dynamic contrast‐enhanced (DCE)‐MRI can assess tumor microvasculature and has demonstrated utility in characterizing
Vaios Hatzoglou, Jamie Tisnado, Alpesh Mehta, Kyung K. Peck, Mariza Daras, Antonio M. Omuro, Kathryn Beal, Andrei I. Holodny   +7 more
doaj   +1 more source

Emerging principles of brain immunology and immune checkpoint blockade in brain metastases.

Brain : a journal of neurology, 2021
Brain metastases are the most common type of brain tumours, harbouring an immune microenvironment that can in principle be targeted via immunotherapy. Elucidating some of the immunological intricacies of brain metastases has opened a therapeutic window ...
Jawad Fares, I. Ulasov, P. Timashev, M. Lesniak   +3 more
semanticscholar   +1 more source

Treatment of brain metastases [PDF]

Biomedical Papers, 2016
Brain metastases are a very common neurological sequela in cancer patients. The ability of current anti-cancer therapies to prolong overall survival is beleaguered by this development in the case of a number of different cancers. This review provides a general overview of relevant treatment modalities, highlights major decision strategies used in ...
Marcel Matzenauer, David Vrana, Bohuslav Melichar   +2 more
openaire   +3 more sources

Methods and results of local treatment of brain metastases in patients with breast cancer [PDF]

, 2016
This article presents methods and results of surgical treatment and radiation therapy of brain metastases in breast cancer patients (brain metastases from breast cancer BMF-BC). Based on the literature data, it was shown that patients with single BMF-BC,
Pluta, Elżbieta, Agnieszka Szadurska, Tomasz Walasek, Mituś, Jerzy, Jerzy W. Mituś, Walasek, Tomasz, Blecharz, Paweł, Elżbieta Pluta, Paweł Blecharz, Jerzy Jakubowicz, Szadurska, Agnieszka, Jakubowicz, Jerzy   +11 more
core   +1 more source

Incidence and gender difference of brain metastases in newly diagnosed follicular thyroid cancer patients

European Thyroid Journal
Background: Population-based estimates of brain metastases in follicular thyroid cancer (FTC) patients with or without distant metastases (DMs) at diagnosis are lacking.
Ruiguo Zhang, Weijian Li, Hui Wang, Wenxin Zhang, Jinyan Chai, Pengpeng Chang, Qiang Jia, Wei Zheng   +7 more
doaj   +1 more source