Results 31 to 40 of about 1,871,454 (260)

Methods and results of local treatment of brain metastases in patients with breast cancer [PDF]

, 2016
This article presents methods and results of surgical treatment and radiation therapy of brain metastases in breast cancer patients (brain metastases from breast cancer BMF-BC). Based on the literature data, it was shown that patients with single BMF-BC,
Pluta, Elżbieta, Agnieszka Szadurska, Tomasz Walasek, Mituś, Jerzy, Jerzy W. Mituś, Walasek, Tomasz, Blecharz, Paweł, Elżbieta Pluta, Paweł Blecharz, Jerzy Jakubowicz, Szadurska, Agnieszka, Jakubowicz, Jerzy   +11 more
core   +1 more source

Serial monitoring of cerebrospinal fluid in patients with leptomeningeal metastases in lung cancer via the Ommaya reservoir as a predictive indicator of therapeutic efficacy and clinical prognosis

npj Precision Oncology
Leptomeningeal metastasis (LM) is a severe neurological complication in patients with lung adenocarcinoma (LUAD), typically indicating terminal stage and poor survival.
Hehui Fang, Haitao Luo, Shujin Li, Naimeng Yan, Shu Xu, Na Liu, Xiaoyue Wang, Ting Xu, Wanwan Cheng, Yong Liu, Chuanyong Yu, Shencun Fang   +11 more
doaj   +1 more source

Incidence and gender difference of brain metastases in newly diagnosed follicular thyroid cancer patients

European Thyroid Journal
Background: Population-based estimates of brain metastases in follicular thyroid cancer (FTC) patients with or without distant metastases (DMs) at diagnosis are lacking.
Ruiguo Zhang, Weijian Li, Hui Wang, Wenxin Zhang, Jinyan Chai, Pengpeng Chang, Qiang Jia, Wei Zheng   +7 more
doaj   +1 more source

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

Identification of CD37, cystatin A, and IL-23A gene expression in association with brain metastasis: analysis of a prospective trial

The International Journal of Biological Markers, 2019
Purpose/Objectives: We aimed to assess the predictive value of a lung cancer gene panel for the development of brain metastases. Materials/Methods: Between 2011 and 2015, 102 patients with lung cancer were prospectively enrolled in a clinical trial in ...
Ammoren Dohm, Jing Su, Emory R. McTyre, James M. Taylor, Lance D. Miller, W. Jeffrey Petty, Fei Xing, Hui-Wen Lo, Linda J. Metheny-Barlow, Stacey O’Neill, Christina Bellinger, Travis Dotson, Boris Pasche, Kounosuke Watabe, Michael D. Chan, Jimmy Ruiz   +15 more
doaj   +1 more source

Brain Metastasis in Patients with Non-Small Cell Lung Cancer: Immunohistochemical Markers

, 2015
Lung cancer is the leading cause of cancer death in developed countries. Because of the lack of diagnostic tools for early detection and of efficient treatment for advanced disease, the prognosis of lung cancer is still poor, with 5-year survival ...
Saad, Ali G, Ali G. Saad
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

The Risk of Hippocampal Metastasis and the Associated High-Risk Factors in 411 Patients With Brain Metastases

Frontiers in Oncology, 2022
Background and AimsTo retrospectively analyze the incidence of hippocampal metastasis and the associated high-risk factors in patients with brain metastases and evaluate the safety of hippocampal avoidance whole-brain radiation therapy (HA-WBRT ...
Peng Xie, Hui Qiao, Huiling Hu, Wenlong Xin, Huanyu Zhang, Ning Lan, Xiaohua Chen, Yan Ma   +7 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source