Results 31 to 40 of about 205,089 (292)

Revisiting Indications for Brain Imaging During the Clinical Staging Evaluation of Lung Cancer

JTO Clinical and Research Reports, 2022
Introduction: Available guidelines are inconsistent as to whether patients with newly diagnosed clinical stage II NSCLC should receive routine brain imaging.
Matthew D. Pichert, MD, Maureen E. Canavan, PhD, MPH, Richard C. Maduka, MD, Andrew X. Li, MD, Theresa Ermer, MD, Peter L. Zhan, MD, Michael Kaminski, BA, Brooks V. Udelsman, MD, MHS, Justin D. Blasberg, MD, MPH, Vincent J. Mase, Jr., MD, Andrew P. Dhanasopon, MD, Daniel J. Boffa, MD, MBA   +11 more
doaj   +1 more source

Regression of experimental NIS-expressing breast cancer brain metastases in response to radioiodide/gemcitabine dual therapy. [PDF]

, 2016
Treating breast cancer brain metastases (BCBMs) is challenging. Na+/I- symporter (NIS) expression in BCBMs would permit their selective targeting with radioiodide (131I-).
Ahmad, Ahn, Carlson, Carrasco, Carrasco, Carrasco, Carrasco, Carrasco, Clarke, Desai, Dirbas, Dominguez, Gambhir, Gonzalez-Angulo, Grollman, Harrington, Haveman, Ikeda, Jhiang, Jhiang, Jhiang, Kalkanis, Kang, Kirova, Lawrence, Lawrence, Lind, Link, Liu, Lorusso, Mier, Morris, Neuwelt, Nishimura, Russell, Schlumberger, Seidman, Smith, Spitzweg, Steeg, Studebaker, Vermorken, Vermorken, Wapnir, Wapnir, Wapnir, Wapnir   +46 more
core   +1 more source

A call for the aggressive treatment of oligometastatic and oligo-recurrent non-small cell lung cancer. [PDF]

, 2012
Metastatic non-small cell lung cancer (NSCLC) carries a dismal prognosis. Clinical evidence suggests the existence of an intermediate, or oligometastatic, state when metastases are limited in number and/or location.
Niibe, Yuzuru, Patel, Pretesh R, Salama, Joseph K, Urbanic, James J, Yoo, David S   +4 more
core   +3 more sources

Linear accelerator-based stereotactic radiosurgery in 140 brain metastases from malignant melanoma [PDF]

, 2015
Background: To retrospectively access outcome and prognostic parameters of linear accelerator-based stereotactic radiosurgery in brain metastases from malignant melanoma. Methods: Between 1990 and 2011 140 brain metastases in 84 patients with malignant
Combs, Stephanie E., Debus, Jürgen, Hauswald, Henrik, Stenke, Alina   +3 more
core   +1 more source

Dynamic contrast‐enhanced MRI perfusion for differentiating between melanoma and lung cancer brain metastases

Cancer Medicine, 2017
Brain metastases originating from different primary sites overlap in appearance and are difficult to differentiate with conventional MRI. Dynamic contrast‐enhanced (DCE)‐MRI can assess tumor microvasculature and has demonstrated utility in characterizing
Vaios Hatzoglou, Jamie Tisnado, Alpesh Mehta, Kyung K. Peck, Mariza Daras, Antonio M. Omuro, Kathryn Beal, Andrei I. Holodny   +7 more
doaj   +1 more source

Phase I Study of Ipilimumab Combined with Whole Brain Radiation Therapy or Radiosurgery for Melanoma Patients with Brain Metastases [PDF]

, 2018
Purpose: We performed a phase I study to determine the maximum tolerable dose (MTD) and safety of ipilimumab with stereotactic radiosurgery (SRS) or whole brain radiotherapy (WBRT) in patients with brain metastases (BM) from melanoma.
Andrews MD, David W., Daskalakis, Constantine, Dicker, Adam, MD, PhD, Eldredge-Hindy, Harriet B., Evans, James J., Farrell, MD, Christopher J, Feeney, Kendra J., Garg, Shivank, Judy, MD, Kevin, Kendra, Kari L., Kim, Lyndon, Kim, MD, Hyun, Liebner, David A., Mastrangelo, Michael, Olencki, Thomas, Palmer, Joshua D., Sato, Takami, Shi, Wenyin, Werner-Wasik, Maria, Williams, Noelle L., Wuthrick, Evan J.   +20 more
core   +2 more sources

Incidence and gender difference of brain metastases in newly diagnosed follicular thyroid cancer patients

European Thyroid Journal
Background: Population-based estimates of brain metastases in follicular thyroid cancer (FTC) patients with or without distant metastases (DMs) at diagnosis are lacking.
Ruiguo Zhang, Weijian Li, Hui Wang, Wenxin Zhang, Jinyan Chai, Pengpeng Chang, Qiang Jia, Wei Zheng   +7 more
doaj   +1 more source

Identification of CD37, cystatin A, and IL-23A gene expression in association with brain metastasis: analysis of a prospective trial

The International Journal of Biological Markers, 2019
Purpose/Objectives: We aimed to assess the predictive value of a lung cancer gene panel for the development of brain metastases. Materials/Methods: Between 2011 and 2015, 102 patients with lung cancer were prospectively enrolled in a clinical trial in ...
Ammoren Dohm, Jing Su, Emory R. McTyre, James M. Taylor, Lance D. Miller, W. Jeffrey Petty, Fei Xing, Hui-Wen Lo, Linda J. Metheny-Barlow, Stacey O’Neill, Christina Bellinger, Travis Dotson, Boris Pasche, Kounosuke Watabe, Michael D. Chan, Jimmy Ruiz   +15 more
doaj   +1 more source

Serial monitoring of cerebrospinal fluid in patients with leptomeningeal metastases in lung cancer via the Ommaya reservoir as a predictive indicator of therapeutic efficacy and clinical prognosis

npj Precision Oncology
Leptomeningeal metastasis (LM) is a severe neurological complication in patients with lung adenocarcinoma (LUAD), typically indicating terminal stage and poor survival.
Hehui Fang, Haitao Luo, Shujin Li, Naimeng Yan, Shu Xu, Na Liu, Xiaoyue Wang, Ting Xu, Wanwan Cheng, Yong Liu, Chuanyong Yu, Shencun Fang   +11 more
doaj   +1 more source

Mutational signatures of synchronous and metachronous brain metastases from lung adenocarcinoma

Experimental Hematology & Oncology, 2023
Brain metastasis (BM) is an important cause of mortality for cancer patients. Many patients were diagnosed with brain metastases at their first visit who have not received any treatment while a subset of patients did not have distant metastases at the ...
Jianing Chen, Hainan Yang, Chao Zhao, Tao Lin, Da Liu, Weiping Hong, Changguo Shan, Cheng Zhou, Ling Bao, Caicun Zhou, Linbo Cai, Chunxia Su, Zhaoming Zhou, Lei Wen   +13 more
doaj   +1 more source