Nature Reviews Disease Primers, 2019 An estimated 20% of all patients with cancer will develop brain metastases, with the majority of brain metastases occurring in those with lung, breast and colorectal cancers, melanoma or renal cell carcinoma. Brain metastases are thought to occur via seeding of circulating tumour cells into the brain microvasculature; within this unique ...
Achrol, Achal Singh +10 more
exaly +8 more sources
Clinical Medicine, 2014 Brain metastases are the most frequent neurological complication of cancer and the most common brain tumour type. Lung and breast cancers, and melanoma are responsible for up to three-quarters of metastatic brain lesions. Most patients exhibit either headache, seizures, focal deficits, cognitive or gait disorders, which severely impair the quality of ...
Jaime, Gállego Pérez-Larraya +1 more
openaire +4 more sources
Ecancermedicalscience, 2012 Brain metastases are the most common neurologic complication related to systemic cancer. With continued improvements in systemic treatment, the incidence is expected to increase. This article reviews the clinical presentation, pathophysiology, prognostic factors, and treatment of metastatic brain tumors.Brain metastases from systemic cancer are up to ...
Christine, Lu-Emerson, April F, Eichler
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Value of screening and follow‐up brain MRI scans in patients with metastatic melanoma
Cancer Medicine, 2021 Background Novel treatments make long‐term survival possible for subsets of patients with melanoma brain metastases. Brain magnetic resonance imaging (MRI) may aid in early detection of brain metastases and inform treatment decisions. This study aimed to
Annemarie C. Eggen +7 more
doaj +1 more source
Stereotactic Radiosurgery Practice Patterns for Brain Metastases in the United States: A National Survey [PDF]
, 2018 Background: Stereotactic radiosurgery (SRS) has emerged as an important modality for the treatment of intracranial metastases. There are currently few established guidelines delineating indications for SRS use and fewer still regarding plan evaluation in
Bhamidipati, Deepak +7 more
core +2 more sources
Outcome of Patients with Non-Small Cell Lung Cancer (NSCLC) and Brain Metastases: Egyptian Experience [PDF]
Research in Oncology, 2016 Background: Lung cancer remains the most common primary tumor responsible for brain metastases making up to 40% to 50% of cases. Brain metastases from NSCLC is associated with poor prognosis. Aim: The aim of this study is to analyze the risk factors and
Salah Elmesidy +5 more
doaj +1 more source
Activity of eribulin mesylate in brain metastasis from breast cancer. a stone in a pond? [PDF]
, 2018 Background: Brain metastases develop in approximately 10-25% of patients with metastatic breast cancer (MBC) and are associated with a very poor prognosis.
Catania, G. +5 more
core +1 more source
The role of EGFR mutation as a prognostic factor in survival after diagnosis of brain metastasis in non-small cell lung cancer: A systematic review and meta-analysis [PDF]
, 2019 Background The brain is a common site for metastasis in non-small-cell lung cancer (NSCLC). This study was designed to evaluate the relationship between the mutational of the epidermal growth factor receptor (EGFR) and overall survival (OS) in NSCLC ...
Han, Yunan +11 more
core +2 more sources
Quality of life (QoL) as predictive mediator variable for survival in patients with intracerebral neoplasma during radiotherapy [PDF]
, 2003 Background: The prognosis for patients with malignant astrocytoma or brain metastases is often fatal despite intensive therapy. Therefore we wished to elucidate whether the quality of life (QoL) is a determinant of overall survival (OAS).
Aydemir, U. +6 more
core +1 more source
Brainstem metastases treated with Gamma Knife stereotactic radiosurgery: the Indiana University Health experience [PDF]
, 2018 Brainstem metastases offer a unique challenge in cancer treatment, yet stereotactic radiosurgery (SRS) has proven to be an effective modality in treating these tumors.
Ansari, Shaheryar +9 more
core +2 more sources