Results 21 to 30 of about 205,089 (292)

Unveiling the tumor immune microenvironment of organ-specific melanoma metastatic sites

Journal for ImmunoTherapy of Cancer, 2022
Background The liver is a known site of resistance to immunotherapy and the presence of liver metastases is associated with shorter progression-free and overall survival (OS) in melanoma, while lung metastases have been associated with a more favorable ...
John F Thompson, Serigne Lo, Ines Pires da Silva, Georgina V Long, Richard A Scolyer, Andrew J Spillane, Robert V Rawson, Tasnia Ahmed, Jordan W Conway, Matteo S Carlino, Ismael A Vergara, James S Wilmott, Grace Heloise Attrill, Tuba N Gide, Robyn P M Saw, Kerwin F Shannon, Brindha Shivalingam, Alexander Maxwell Menzies   +17 more
doaj   +1 more source

Characterization of the immune microenvironment in brain metastases from different solid tumors

Cancer Medicine, 2020
Background Brain metastases are one of the most common intracranial neoplasms. Increasing evidence have indicated that systemic immunotherapy may provide long‐term benefits for brain metastases.
Jinling Jiang, Lihong Wu, Fei Yuan, Jun Ji, Xiaojing Lin, Wanning Yang, Junwei Wu, Min Shi, Hui Yang, Yanna Ma, Xue Song, Zhenggang Zhu, Henghui Zhang, Jun Zhang   +13 more
doaj   +1 more source

Longitudinal MRI evaluation of intracranial development and vascular characteristics of breast cancer brain metastases in a mouse model. [PDF]

PLoS ONE, 2013
Longitudinal MRI was applied to monitor intracranial initiation and development of brain metastases and assess tumor vascular volume and permeability in a mouse model of breast cancer brain metastases.
Heling Zhou, Min Chen, Dawen Zhao
doaj   +1 more source

Erlotinib in patients with previously irradiated, recurrent brain metastases from non-small cell lung cancer: Two case reports [PDF]

, 2008
Background: With the current improvements in primary lung care, the long-term control of brain metastases becomes a clinical challenge. No established therapeutic approaches exist for cranial relapse after response to previous radiotherapy and systemic ...
Abrey LE, Barbara Poellinger, Ceresoli GR, Delattre Y, Horst Wagner, Hotta K, Joachim von Pawel, Khantia D, Lai CS, Namba Y, Regine WF, Rodrigus P, Thomas Duell, Zabel A   +13 more
core   +1 more source

Small vessel ischemic disease of the brain and brain metastases in lung cancer patients. [PDF]

PLoS ONE, 2009
Brain metastases occur commonly in patients with lung cancer. Small vessel ischemic disease is frequently found when imaging the brain to detect metastases.
Peter J Mazzone, Nicola Marchi, Vince Fazio, J Michael Taylor, Thomas Masaryk, Luke Bury, Tarek Mekhail, Damir Janigro   +7 more
doaj   +1 more source

Emerging treatment options for the management of brain metastases in patients with HER2-positive metastatic breast cancer. [PDF]

, 2013
The widespread use of trastuzumab in the past decade has led to a significant and measureable improvement in the survival of patients with human epidermal growth factor receptor-2 (HER2) overexpressing breast cancer, and in many ways has redefined the ...
Chien, A Jo, Rugo, Hope S
core   +1 more source

Brain and spinal cord metastases with seminoma: A case report

IJU Case Reports, 2022
Introduction Brain and spinal cord metastases from testicular cancer occur rarely, and metastases with seminoma are extremely rare. Case presentation A 42‐year‐old man who was diagnosed with seminoma and multiple metastases underwent first‐line and ...
Tetsuya Yumioka, Shuichi Morizane, Karen Makishima, Tadashi Adachi, Emika Moriyasu, Hideto Iwamoto, Katsuya Hikita, Masashi Honda, Yoshihisa Umekita, Atsushi Takenaka   +9 more
doaj   +1 more source

Immune suppressive microenvironment in brain metastatic non-small cell lung cancer: comprehensive immune microenvironment profiling of brain metastases versus paired primary lung tumors (GASTO 1060)

OncoImmunology, 2022
Lung cancer is one of the most common causes of brain metastases and is always associated with poor prognosis. We investigated the immunophenotypes of primary lung tumors and paired brain metastases, as well as immunophenotypes in the synchronous group ...
Meichen Li, Xue Hou, Ke Sai, Lihong Wu, Jing Chen, Baishen Zhang, Na Wang, Lijia Wu, Hongbo Zheng, Jiao Zhang, Yonggao Mou, Likun Chen   +11 more
doaj   +1 more source

Characteristics and treatments of large cystic brain metastasis: radiosurgery and stereotactic aspiration. [PDF]

, 2015
Brain metastasis represents one of the most common causes of intracranial tumors in adults, and the incidence of brain metastasis continues to rise due to the increasing survival of cancer patients. Yet, the development of cystic brain metastasis remains
Cheok, Stephanie, Chung, Lawrance K, Kim, Chang Jin, Kim, Jeong Hoon, Kim, Moinay, Kwon, Do Hoon, Lee, Percy, Tenn, Stephen, Thill, Kimberly, Ung, Nolan, Voth, Brittany, Yang, Isaac   +11 more
core   +1 more source

Patient-Specific Fetal Dose Determination for Multi-Target Gamma Knife Radiosurgery: Computational Model and Case Report. [PDF]

, 2017
A 42-year-old woman at 29 weeks gestation via in vitro fertilization who presented with eight metastatic brain lesions received Gamma Knife stereotactic radiosurgery (GKSRS) at our institution. In this study, we report our clinical experience and a ...
Braunstein, Steve, Ma, Lijun, McDermott, Michael, Paulsson, Anna K, Phillips, Justin, Sneed, Patricia K, Theodosopoulos, Philip V   +6 more
core   +1 more source