Results 21 to 30 of about 2,926,291 (344)

Radiation Therapy for Brain Metastases: ASCO Guideline Endorsement of ASTRO Guideline

Journal of Clinical Oncology, 2022
PURPOSE American Society of Radiation Oncology (ASTRO) has developed a guideline on appropriate radiation therapy for brain metastases. ASCO has a policy and set of procedures for endorsing clinical practice guidelines that have been developed by other ...
D. Schiff, H. Messersmith, P. Brastianos, P. Brown, S. Burri, I. Dunn, L. Gaspar, V. Gondi, J. Jordan, Julia Maués, N. Mohile, Navid Redjal, G. Stevens, E. Sulman, M. J. van den Bent, H. Wallace, G. Zadeh, M. Vogelbaum   +17 more
semanticscholar   +1 more source

Serum Biomarkers Associated with Clinical Outcomes Fail to Predict Brain Metastases in Patients with Stage IV Non-Small Cell Lung Cancers. [PDF]

PLoS ONE, 2016
Lung cancers account for the majority of brain metastases which pose major therapeutic challenges. Biomarkers prognosticating for the development of brain metastases in patients with non-small cell lung cancers (NSCLC) may improve personalized care.
Bob T Li, Emil Lou, Meier Hsu, Helena A Yu, Jarushka Naidoo, Marjorie G Zauderer, Camelia Sima, Melissa L Johnson, Mariza Daras, Lisa M DeAngelis, Martin Fleisher, Mark G Kris, Christopher G Azzoli   +12 more
doaj   +1 more source

Brain metastases.

Ecancermedicalscience, 2012
Brain metastases are the most common neurologic complication related to systemic cancer. With continued improvements in systemic treatment, the incidence is expected to increase. This article reviews the clinical presentation, pathophysiology, prognostic factors, and treatment of metastatic brain tumors.Brain metastases from systemic cancer are up to ...
Christine, Lu-Emerson, April F, Eichler
  +7 more sources

Mutational profiles of primary pulmonary adenocarcinoma and paired brain metastases disclose the importance of KRAS mutations. [PDF]

, 2021
BACKGROUND Brain metastases present a significant complication in lung cancer with an unmet therapeutic need. METHODS In this single-centre, retrospective study, we genotyped a clinico-pathologically well-annotated cohort of consecutively ...
Berezowska, Sabina, Schmid, R.A., Fung, C., Scherz, Amina, Herrmann, Evelyn, Kashani, Elham, Berezowska, S., Kündig, Alexandra, Ermis, E., Kashani, E., Ermis, Ekin, Schmid, Ralph A., Vassella, Erik, Kündig, A., Vassella, E., Zens, Philipp, Scherz, A., Fung, Christian, Herrmann, E., Zens, P.   +19 more
core   +1 more source

Hippocampal Avoidance During Whole-Brain Radiotherapy Plus Memantine for Patients With Brain Metastases: Phase III Trial NRG Oncology CC001.

Journal of Clinical Oncology, 2020
PURPOSE Radiation dose to the neuroregenerative zone of the hippocampus has been found to be associated with cognitive toxicity. Hippocampal avoidance (HA) using intensity-modulated radiotherapy during whole-brain radiotherapy (WBRT) is hypothesized to ...
P. Brown, V. Gondi, S. Pugh, W. Tomé, J. Wefel, T. Armstrong, J. Bovi, C. Robinson, A. Konski, D. Khuntia, D. Grosshans, T. Benzinger, D. Bruner, M. Gilbert, D. Roberge, V. Kundapur, K. Devisetty, Sunjay A. Shah, K. Usuki, B. Anderson, B. Stea, H. Yoon, Jing Li, N. Laack, T. Kruser, S. Chmura, W. Shi, S. Deshmukh, M. Mehta, L. Kachnic   +29 more
semanticscholar   +1 more source

Cellular Architecture of Human Brain Metastases

Cell, 2022
SUMMARY Brain metastasis (BrM) is the most common form of brain cancer, characterized by neurologic disability and abysmal prognosis. Unfortunately, our understanding of the biology underlying human BrMs remains rudimentary.
Hugo Gonzalez, Wenbin Mei, I. Robles, C. Hagerling, Breanna M. Allen, Trine Line Hauge Okholm, Ankitha Nanjaraj, T. Verbeek, Sandhya Kalavacherla, Merel van Gogh, Stephen Georgiou, M. Daras, J. Phillips, M. Spitzer, J. Roose, Z. Werb   +15 more
semanticscholar   +1 more source

A National Consensus Survey for Current Practice in Brain Tumor Management III: Brain Metastasis and Primary Central Nervous System Lymphoma [PDF]

, 2020
Background: The Guideline Working Group of the Korean Society for Neuro-Oncology (KSNO) conducted the nationwide questionnaire survey for diverse queries facing to treat patients with brain tumor.
김세훈, 윤홍인, 장종희
core   +1 more source

Value of screening and follow‐up brain MRI scans in patients with metastatic melanoma

Cancer Medicine, 2021
Background Novel treatments make long‐term survival possible for subsets of patients with melanoma brain metastases. Brain magnetic resonance imaging (MRI) may aid in early detection of brain metastases and inform treatment decisions. This study aimed to
Annemarie C. Eggen, Thijs T. Wind, Ingeborg Bosma, Miranda C. A. Kramer, Peter Jan vanLaar, Hiska L. van derWeide, Geke A. P. Hospers, Mathilde Jalving   +7 more
doaj   +1 more source

Differential Distribution of Brain Metastases from Non-Small Cell Lung Cancer Based on Mutation Status

Brain Sciences, 2023
Non-small cell lung cancer (NSCLC) has a high rate of brain metastasis. The purpose of this study was to assess the differential distribution of brain metastases from primary NSCLC based on mutation status.
Bihong T. Chen, Taihao Jin, Ningrong Ye, Sean W. Chen, Russell C. Rockne, Stephanie Yoon, Isa Mambetsariev, Ebenezer Daniel, Ravi Salgia   +8 more
doaj   +1 more source

Erlotinib in patients with previously irradiated, recurrent brain metastases from non-small cell lung cancer: Two case reports [PDF]

, 2008
Background: With the current improvements in primary lung care, the long-term control of brain metastases becomes a clinical challenge. No established therapeutic approaches exist for cranial relapse after response to previous radiotherapy and systemic ...
Pawel, Joachim, Wagner, Horst, Poellinger, Barbara, Duell, Thomas   +3 more
core   +1 more source