Results 141 to 150 of about 193,384 (260)

Tumor Exosomal L1 Cell Adhesion Molecule Promotes Brain Metastasis of Lung Cancer. [PDF]

Research (Wash D C)
Kim DH, Lee CW, Choi YJ, Kim DS, Ban K, Hong J, Moon GJ, Kim SY, Pack CG, Baek IJ, Baek IJ, Jeong JY, Woo DC, Oh JH, Sung CO, Kim K, Kim HY, Jung HY, Ji W, Kim MJ, Choi CM, Lee JC, Rho JK.   +22 more
europepmc   +1 more source

Natural Resistance to Ovarian Hyperstimulation Syndrome in Estrildid Finches Reveals Macrophage GPR183 as a Potential Therapeutic Target

Advanced Science, EarlyView.
Ovarian macrophage depletion reverses OHSS resistance in estrildid finches and exacerbates OHSS symptoms in rats. Activating macrophage GPR183 alleviates OHSS by reducing pro‐inflammatory factors, increasing immunomodulatory molecules, remodeling CD44/SDC4‐mediated communication, and restoring immune homeostasis.
Xiaofei Yan, Yongjie Huang, Jiabao Yang, Su Ma, Songsong Liu, Xuan Huang, Juergen Brosius, Huaping Zheng, Bing Yao, Li Chen, Shanshan Lai, Cheng Deng   +11 more
wiley   +1 more source

Deciphering brain metastasis in epithelial ovarian cancer: multimodal analysis and potential biomarkers. [PDF]

NPJ Precis Oncol
Trozzi R, Salvi M, Karimi M, Minucci A, Raspaglio G, De Donato M, Buttarelli M, Piermattei A, Vaccaro L, Grimaldi A, De Santis R, Massa M, Sillano F, Giacò L, Mastrantoni L, Iacobelli V, Camarda F, Cesana M, Duranti S, Sassu MC, Mattogno P, Fagotti A, Marchetti C, Scambia G, Nero C, Cacchiarelli D.   +25 more
europepmc   +1 more source

Combining Spatial Multi‐Omics Data to Decipher Spatial Domains and Elucidate Cell Heterogeneity Based on Self‐Supervised Graph Learning

Advanced Science, EarlyView.
A self‐supervised multi‐view graph fusion framework integrates spatial multi‐omics, excelling in domain identification and denoising. It reconstructs spatial pseudo‐expression, jointly analyzes multi‐omics data, infers RNA velocity, predicts spatial omics features from single‐cell multi‐omics, and detects spatially dark genes and transcription factors,
Yuejing Lu, Rui Qiao, Ying Li, Junhong Li, Nuoya Yue, Jing Ge, Jiao Wang, Luonan Chen, Peiluan Li   +8 more
wiley   +1 more source

A Skull Bone Marrow‐to‐Brain Axis Links Osteoblastic Activity to Myeloid Cell Trafficking, Cerebral Blood Flow, and Cognition in Alzheimer's Progression

Advanced Science, EarlyView.
This study reveals that Alzheimer's disease–linked APP expression in bone‐forming cells drives skull bone marrow remodeling and alters its vascular connections to the brain. These changes disrupt immune cell trafficking, cerebral blood flow, and cognition. Targeting bone marrow macrophages restores brain function, highlighting a previously unrecognized
Lei Xiong, Dong Sun, Hao‐Han Guo, Daehoon Lee, Zhipeng Liu, Lin Mei, Wen‐Cheng Xiong   +6 more
wiley   +1 more source

Modeling dose to normal brain following hypofractionated stereotactic radiotherapy to a single brain metastasis. [PDF]

J Appl Clin Med Phys
Johns E, Hargrave C, Nissen L, Barry TJ, Bernard A, Pinkham MB.   +5 more
europepmc   +1 more source

Bona Fide Intersegmental Plane Hepatectomy Along the Glissonean Branches (BIPHG)

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT This review traces the author's personal journey over three decades in the evolution of liver resection techniques, culminating in the proposal of the Bona Fide Intersegmental Plane Hepatectomy Along Glissonean Branches (BIPHG). Beginning with pioneering experiences in laparoscopic and robotic liver surgeries, the author highlights key ...
Go Wakabayashi, Taiga Wakabayashi
wiley   +1 more source

Downregulated lysyl oxidase in plasma extracellular vesicles: a biomarker linked to brain metastasis risk in lung adenocarcinoma. [PDF]

BMC Med
Li J, Pei Y, Sun JL, Hu F, Yang HX, Zhou J, Wu CT, Hao X, Gong W, Yao Y, Liu Y.   +10 more
europepmc   +1 more source

Artificial Intelligence for Bone: Theory, Methods, and Applications

Advanced Intelligent Discovery, EarlyView.
Advances in artificial intelligence (AI) offer the potential to improve bone research. The current review explores the contributions of AI to pathological study, biomarker discovery, drug design, and clinical diagnosis and prognosis of bone diseases. We envision that AI‐driven methodologies will enable identifying novel targets for drugs discovery. The
Dongfeng Yuan, Haicang Zhang, Liping Tong, Di Chen   +3 more
wiley   +1 more source

Clinicopathological characteristics and prognosis of brain metastasis in non-small cell lung cancer: A retrospective study. [PDF]

Medicine (Baltimore)
Fu X, Liu Q, Jia J, Wang M.
europepmc   +1 more source