Results 151 to 160 of about 193,384 (260)

Toward Predictable Nanomedicine: Current Forecasting Frameworks for Nanoparticle–Biology Interactions

Advanced Intelligent Discovery, EarlyView.
Predictive models successfully screen nanoparticles for toxicity and cellular uptake. Yet, complex biological dynamics and sparse, nonstandardized data limit their accuracy. The field urgently needs integrated artificial intelligence/machine learning, systems biology, and open‐access data protocols to bridge the gap between materials science and safe ...
Mariya L. Ivanova, Michael Nicholls, Nicola Russo, Gueorgui Mihaylov, Konstantin Nikolic   +4 more
wiley   +1 more source

Associations of three immune inflammatory markers with the risk of brain metastasis from lung cancer: a systematic review and meta-analysis. [PDF]

Front Oncol
Liu M, Shi Y, Chen A, Hu X.
europepmc   +1 more source

KDLM: Lightweight Brain Tumor Segmentation via Knowledge Distillation

Advanced Intelligent Systems, EarlyView.
A lightweight student network is designed, which is based on multiscale and multilevel feature fusion and combined with the residual channel attention mechanism to achieve efficient feature extraction and fusion with very few parameters. A dual‐teacher collaborative knowledge distillation framework is proposed.
Baotian Li, Haoyu Tang, Jun Zhu, Fang Fang Gou, Jia Wu   +4 more
wiley   +1 more source

Clinicopathologic Characteristics of Brain Metastasis of Pancreatic Ductal Adenocarcinoma. [PDF]

Am J Surg Pathol
Elzamly S, Alsawas M, Yousef MMG, Zhao D, Katz MH, Prakash LR, Wang H, Li Z, Wolff RA, Maitra A, Wang H.   +10 more
europepmc   +1 more source

Zebrafish and CRISPR—A synergistic approach to decipher and cure human diseases

Animal Models and Experimental Medicine, EarlyView.
Zebrafish, with high genetic homology to humans, serves as a powerful vertebrate model for disease modeling and drug discovery. Integration of CRISPR/Cas9 technology enables precise genome editing, facilitating the development of translational models for human diseases.
Manikandan Sivaprakasam, Aashika Raagavi Jeanpierre, Salma Mohammed, Rajesh Srinivasan, Aman Kumar Mohanty   +4 more
wiley   +1 more source

Tumor Mutational Burden-High Intrahepatic Cholangiocarcinoma Presenting with Solitary Brain Metastasis: A Case of Precision Oncology. [PDF]

Surg Case Rep
Maehata T, Ushida Y, Sugawara G, Yamashita Y, Inoue M.   +4 more
europepmc   +1 more source

A preclinical mouse model mimicking the ovarian cancer‐induced estrogen deficiency‐depression axis

Animal Models and Experimental Medicine, EarlyView.
A preclinical mouse model of ovarian cancer–related depression was developed by combining intraperitoneal tumor cell injection, ovariectomy, and chronic restraint stress. The model replicates key clinical features including estrogen deficiency, depressive‐like behaviors, and tumor progression, and provides a reliable tool for studying the endocrine ...
Jiamin Liu, Yafei Yang, Chunxi Liu, Danting Wen, Tingyu Zhao, Ping Xie, Jing Xiao   +6 more
wiley   +1 more source

Association of sarcopenia with survival and treatment response in brain metastasis of non-small cell lung cancer. [PDF]

Sci Rep
Schmidt L, Krenzlin H, Schmitz A, Jankovic D, Dauth A, Alessandri B, Sommer C, Brockman MA, Ringel F, Keric N.   +9 more
europepmc   +1 more source

Cancer therapy‐induced ototoxicity: Current challenges and emerging management strategies

Animal Models and Experimental Medicine, EarlyView.
This review comprehensively examines the key risk factors for cancer therapy‐induced ototoxicity, including cumulative drug dose, genetic susceptibility, and combined treatment regimens. It highlights current challenges in ototoxicity monitoring, such as insufficient timeliness and limited clinical adoption, and advocates for standardized auditory ...
Yuqi Huang, Baoying Xu, Xinru Chen, Yu Chen, Dehong Yu   +4 more
wiley   +1 more source