Results 21 to 30 of about 2,048,757 (259)

Brain metastasis from ovarian carcinoma: Analysis of eight cases from a single radiotherapy center

open access: yesTaiwanese Journal of Obstetrics & Gynecology, 2020
Objective: Brain metastasis from epithelial ovarian carcinoma (EOC) is rarely seen having rate of 1–3% with very poor prognosis. Studies on brain metastatic EOC is limited with low number of participants.
Zumrut Bahat   +2 more
doaj   +1 more source

Gamma Knife Radiosurgery of Brain Metastasis from Malignant Pleural Mesothelioma : Report of Three Cases with Autopsy Study in a Case [PDF]

open access: yes, 2014
2014-02The median survival time of malignant pleural mesothelioma (MPM) has been 9 months. Given the short survival, there have been only few cases in which brain metastases have been diagnosed and treated before death.
TORIYAMA, TAKANOBU   +6 more
core   +1 more source

ProNGF promotes brain metastasis through TrkA/EphA2 induced Src activation in triple negative breast cancer cells

open access: yesExperimental Hematology & Oncology, 2023
Background Triple-Negative Breast Cancer is particularly aggressive, and its metastasis to the brain has a significant psychological impact on patients' quality of life, in addition to reducing survival.
Julien Cicero   +27 more
doaj   +1 more source

Vascular co-option in brain metastasis. [PDF]

open access: yes, 2020
Vascular co-option by brain metastasis-initiating cells has been demonstrated as a critical step in organ colonization. The physical interaction between the cancer cell and the endothelial cell is mediated by integrins and L1CAM and could be involved in ...
Valiente, Manuel, García-Gómez, Pedro
core   +1 more source

Blood–Brain Barrier, Cell Junctions, and Tumor Microenvironment in Brain Metastases, the Biological Prospects and Dilemma in Therapies

open access: yesFrontiers in Cell and Developmental Biology, 2021
Brain metastasis is the most commonly seen brain malignancy, frequently originating from lung cancer, breast cancer, and melanoma. Brain tumor has its unique cell types, anatomical structures, metabolic constraints, and immune environment, which namely ...
Zhiyuan Guan   +5 more
doaj   +1 more source

Nicotine promotes brain metastasis by polarizing microglia and suppressing innate immune function.

open access: yes, 2020
Up to 40% of lung cancer patients develop brain metastasis, and the median survival of these patients remains less than 6 months. Smoking is associated with lung cancer. However, how smoking impacts the development of brain metastasis remains elusive. We
Watabe, Kounosuke   +15 more
core   +1 more source

Outcomes of brain metastasis in high-grade bone and soft tissue sarcoma: An analysis of clinicopathological characteristics and survival data

open access: yesRare Tumors, 2021
Brain metastases in sarcoma are exceedingly rare, with few published series documenting ranges from 1% to 8%. This study investigated the outcomes of sarcoma patients with brain metastases using a population-based analysis.
Charles A Gusho   +2 more
doaj   +1 more source

Erlotinib in patients with previously irradiated, recurrent brain metastases from non-small cell lung cancer: Two case reports [PDF]

open access: yes, 2008
Background: With the current improvements in primary lung care, the long-term control of brain metastases becomes a clinical challenge. No established therapeutic approaches exist for cranial relapse after response to previous radiotherapy and systemic ...
Pawel, Joachim   +3 more
core   +1 more source

Inflammatory Activation of Astrocytes Facilitates Melanoma Brain Tropism via the CXCL10-CXCR3 Signaling Axis

open access: yesCell Reports, 2019
Summary: Melanoma is the deadliest skin cancer due to its high rate of metastasis, frequently to the brain. Brain metastases are incurable; therefore, understanding melanoma brain metastasis is of great clinical importance.
Hila Doron   +19 more
doaj   +1 more source

Frequency of metastases within the hypothalamic–pituitary area and the associated high-risk factors in patients with brain metastases

open access: yesFrontiers in Neurology, 2023
ObjectiveBrain radiotherapy often results in impairment of hypothalamic–pituitary (HT-P) function, which in turn causes secretory dysfunction of related hormones.
Peng Xie   +9 more
doaj   +1 more source

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