Results 251 to 260 of about 26,410 (296)

11.7T Diffusion Magnetic Resonance Imaging and Tractography to Probe Human Brain Organoid Microstructure. [PDF]

Biol Psychiatry Glob Open Sci
Versace A, Hitchens TK, Wallace CT, Watkins SC, D'Aiuto L.   +4 more
europepmc   +1 more source

Immune involvement in neuropsychiatric disorders: Insights from single‐cell transcriptomic studies

Psychiatry and Clinical Neurosciences, EarlyView.
Neuropsychiatric disorders pose profound challenges to both research and treatment, largely due to their clinical heterogeneity and the limited understanding of their underlying biological mechanisms. While bulk RNA sequencing (bulk RNA‐seq) has been widely used to study gene expression, it cannot resolve cell‐type‐specific signals or detect rare ...
Tsutomu Takeda, Michihiro Toritsuka, Hiroto Tamakoshi, Nakao Iwata, Manabu Makinodan   +4 more
wiley   +1 more source

Rigor and reproducibility in human brain organoid research: Where we are and where we need to go. [PDF]

Stem Cell Reports
Sandoval SO, Cappuccio G, Kruth K, Osenberg S, Khalil SM, Méndez-Albelo NM, Padmanabhan K, Wang D, Niciu MJ, Bhattacharyya A, Stein JL, Sousa AMM, Waxman EA, Buttermore ED, Whye D, Sirois CL, Cross-IDDRC Human Stem Cell Consortium, Williams A, Maletic-Savatic M, Zhao X.   +19 more
europepmc   +1 more source

The Donation of Human Biological Material for Brain Organoid Research: The Problems of Consciousness and Consent. [PDF]

Sci Eng Ethics
Kataoka M, Gyngell C, Savulescu J, Sawai T.   +3 more
europepmc   +1 more source

Editorial: Stem cell-derived retinal and brain organoid culture for disease modeling. [PDF]

Front Cell Neurosci
Cheng L, Caldwell MA, Cho KS, Mellough CB.   +3 more
europepmc   +1 more source

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Polarizing brain organoids

Nature Biotechnology, 2019
Human brain organoids are endowed with regional topography using engineered signaling centers.
Yuki Miura, Sergiu P. Pașca
openaire   +2 more sources

Brain organoids restore cortical damage

Cell Stem Cell, 2023
Cortical damage is irreparable and poses a challenge to regenerative medicine. Whether brain organoids can compensate for injured brain regions remains unclear. In this issue of Cell Stem Cell, Jgamadze et al. report that human forebrain organoids transplanted into the rat visual system show long-term structural connectivity and the restoration of ...
Nazlican, Altinisik, Dhanasekaran, Rathinam, Minh, Tran, Jay, Gopalakrishnan   +3 more
openaire   +2 more sources

Interdisciplinary approaches to brain organoid biology

Folia Pharmacologica Japonica, 2023
Embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) have been widely used as materials for regenerative medicine and for modeling development and disease because of their pluripotency to differentiate into all cell types of the body.
Tomoki, Kodera, Fumitaka, Osakada
openaire   +2 more sources