Results 251 to 260 of about 26,891 (293)

11.7T Diffusion Magnetic Resonance Imaging and Tractography to Probe Human Brain Organoid Microstructure. [PDF]

Biol Psychiatry Glob Open Sci
Versace A, Hitchens TK, Wallace CT, Watkins SC, D'Aiuto L.   +4 more
europepmc   +1 more source

Rigor and reproducibility in human brain organoid research: Where we are and where we need to go. [PDF]

Stem Cell Reports
Sandoval SO, Cappuccio G, Kruth K, Osenberg S, Khalil SM, Méndez-Albelo NM, Padmanabhan K, Wang D, Niciu MJ, Bhattacharyya A, Stein JL, Sousa AMM, Waxman EA, Buttermore ED, Whye D, Sirois CL, Cross-IDDRC Human Stem Cell Consortium, Williams A, Maletic-Savatic M, Zhao X.   +19 more
europepmc   +1 more source

The Donation of Human Biological Material for Brain Organoid Research: The Problems of Consciousness and Consent. [PDF]

Sci Eng Ethics
Kataoka M, Gyngell C, Savulescu J, Sawai T.   +3 more
europepmc   +1 more source

Editorial: Stem cell-derived retinal and brain organoid culture for disease modeling. [PDF]

Front Cell Neurosci
Cheng L, Caldwell MA, Cho KS, Mellough CB.   +3 more
europepmc   +1 more source

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Polarizing brain organoids

Nature Biotechnology, 2019
Human brain organoids are endowed with regional topography using engineered signaling centers.
Yuki Miura, Sergiu P. Pașca
openaire   +2 more sources

Brain organoids restore cortical damage

Cell Stem Cell, 2023
Cortical damage is irreparable and poses a challenge to regenerative medicine. Whether brain organoids can compensate for injured brain regions remains unclear. In this issue of Cell Stem Cell, Jgamadze et al. report that human forebrain organoids transplanted into the rat visual system show long-term structural connectivity and the restoration of ...
Nazlican, Altinisik, Dhanasekaran, Rathinam, Minh, Tran, Jay, Gopalakrishnan   +3 more
openaire   +2 more sources

Interdisciplinary approaches to brain organoid biology

Folia Pharmacologica Japonica, 2023
Embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) have been widely used as materials for regenerative medicine and for modeling development and disease because of their pluripotency to differentiate into all cell types of the body.
Tomoki, Kodera, Fumitaka, Osakada
openaire   +2 more sources

Microinstrumentation for Brain Organoids

Advanced Healthcare Materials
AbstractBrain organoids are three‐dimensional aggregates of self‐organized differentiated stem cells that mimic the structure and function of human brain regions. Organoids bridge the gaps between conventional drug screening models such as planar mammalian cell culture, animal studies, and clinical trials.
Devan Patel, Saniya Shetty, Chris Acha, Itzy E. Morales Pantoja, Alice Zhao, Derosh George, David H. Gracias   +6 more
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Modeling traumatic brain injury with human brain organoids

Current Opinion in Biomedical Engineering, 2020
Traumatic brain injury (TBI) remains a prominent public health concern despite several decades of attempts to develop therapies for the associated neurological and cognitive deficits. Effective models of this condition are imperative for better defining its pathophysiology and testing therapeutics.
Dennis Jgamadze, Victoria E. Johnson, John A. Wolf, D. Kacy Cullen, Hongjun Song, Guo-li Ming, Douglas H. Smith, H. Isaac Chen   +7 more
openaire   +2 more sources