Results 111 to 120 of about 3,034,655 (354)

Diverting glial glycolytic flux towards neurons is a memory-relevant role of Drosophila CRH-like signalling

open access: yesNature Communications
An essential role of glial cells is to comply with the large and fluctuating energy needs of neurons. Metabolic adaptation is integral to the acute stress response, suggesting that glial cells could be major, yet overlooked, targets of stress hormones ...
Raquel Francés   +3 more
doaj   +1 more source

Primed to Sleep: The Dynamics of Synaptic Plasticity Across Brain States

open access: yesFrontiers in Systems Neuroscience, 2019
It is commonly accepted that brain plasticity occurs in wakefulness and sleep. However, how these different brain states work in concert to create long-lasting changes in brain circuitry is unclear.
J. Seibt, M. Frank
semanticscholar   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

LATERODORSAL NUCLEUS OF THE THALAMUS HEAD DIRECTION-TUNED CELLS CONTRIBUTION TO LONG-TERM CONTEXTUAL FEAR MEMORY CONSOLIDATION.

open access: yesIBRO Neuroscience Reports, 2023
José Casanova   +3 more
doaj   +1 more source

Rapid and dynamic processing of face pareidolia in the human brain

open access: yesNature Communications, 2020
The human brain is specialised for face processing, yet sometimes objects are perceived as illusory faces. Here, the authors show that illusory faces are initially represented similarly to real faces, but the representation quickly transforms into one ...
Susan G. Wardle   +3 more
doaj   +1 more source

Brain Modularity: A Biomarker of Intervention-related Plasticity.

open access: yesTrends in Cognitive Sciences, 2019
Interventions using methods such as cognitive training and aerobic exercise have shown potential to enhance cognitive abilities. However, there is often pronounced individual variability in the magnitude of these gains.
C. Gallen, M. D’Esposito
semanticscholar   +1 more source

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu   +10 more
wiley   +1 more source

The role of raptor during brain development and in adult forebrain neurons [PDF]

open access: yes, 2012
mTOR is a serine/threonine protein kinase that appears in two functionally distinct multi-protein complexes. mTOR together with the scaffold protein raptor forms mTOR complex1 (mTORC1) that is inhibited in its function by rapamycin.
Lustenberger, Regula Maria
core   +1 more source

Early-life stress impairs acquisition and retrieval of fear memories: sex-effects, corticosterone modulation, and partial prevention by targeting glucocorticoid receptors at adolescent age

open access: yesNeurobiology of Stress
The early postnatal period is a sensitive time window that is characterized by several neurodevelopmental processes that define neuronal architecture and function later in life.
Jeniffer Sanguino-Gómez   +1 more
doaj   +1 more source

The m6A‐epitranscriptomic signature in neurobiology: from neurodevelopment to brain plasticity

open access: yesJournal of Neurochemistry, 2018
Research over the past decade has provided strong support for the importance of various epigenetic mechanisms, including DNA and histone modifications in regulating activity‐dependent gene expression in the mammalian central nervous system. More recently,
Jocelyn Widagdo, V. Anggono
semanticscholar   +1 more source

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