Results 91 to 100 of about 3,034,655 (354)
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Exploring brain functional plasticity in world class gymnasts: a network analysis
, 2016 Long-term motor skill learning can induce plastic structural and functional reorganization of the brain. Our previous studies detected brain structural plasticity related to long-term intensive gymnastic training in world class gymnasts (WCGs).
Wang, Junjing +10 more
core +1 more source
From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care
Molecular Oncology, EarlyView.Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard +8 more
wiley +1 more source
Music and the brain: disorders of musical listening
, 2006 The study of the brain bases for normal musical listening has advanced greatly in the last 30 years. The evidence from basic and clinical neuroscience suggests that listening to music involves many cognitive components with distinct brain substrates ...
Stewart, Lauren +10 more
core +1 more source
The plasticity of near space: evidence for contraction [PDF]
, 2009 The distinction between near space and the space farther away has been well established, as has the relation of this distinction to arm length. Recent studies provide evidence for the plasticity of near space, showing that it is possible to expand its ...
Longo, Matthew R., Lourenco, S.F.
core +1 more source
eLifeRelevance-based selectivity and high energy cost are two distinct features of long-term memory (LTM) formation that warrant its default inhibition. Spaced repetition of learning is a highly conserved cognitive mechanism that can lift this inhibition ...
Typhaine Comyn +3 more
doaj +1 more source
BMC Psychiatry, 2022 Background Several risk factors for anxious-depressive symptomatology during the COVID-19 pandemic have been established. However, few studies have examined the relationship between personality traits, hardiness, and such symptomatology during the ...
Espen Rasmussen Lassen +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
BMC PsychiatryBackground B4DT is a concentrated treatment format with prolonged sessions of exposure and ritual prevention (ERP) delivered over four consecutive days.
Solvei Harila Skjold +5 more
doaj +1 more source
Scientific Reports, 2017 The capacity to respond to novel events is crucial for adapting to the constantly changing environment. Here, we recorded 29-channel Event Related Brain Potentials (ERPs) during an active auditory novelty oddball paradigm and used for the first time ...
Adrià Vilà-Balló +6 more
doaj +1 more source