Results 81 to 90 of about 3,034,655 (354)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Activity-dependent plasticity in visual forebrain areas of the zebra finch

, 1996
Rollenhagen A, Bischof H-J. Activity-dependent plasticity in visual forebrain areas of the zebra finch. Behavioural Brain Research.
Rollenhagen, Astrid, Astrid Rollenhagen, Hans-Joachim Bischof, Bischof, Hans-Joachim   +3 more
core   +1 more source

Functional partitioning of sentence processing and emotional prosody in the right perisylvian cortex after perinatal stroke

Scientific Reports
In healthy adults different language abilities—sentence processing versus emotional prosody—are supported by the left (LH) versus the right hemisphere (RH), respectively.
Kelly C. Martin, Anna Seydell-Greenwald, Peter E. Turkeltaub, Catherine E. Chambers, William D. Gaillard, Elissa L. Newport   +5 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Stable inhibition-related inferior frontal hypoactivation and fronto-limbic hyperconnectivity in obsessive–compulsive disorder after concentrated exposure therapy

NeuroImage: Clinical, 2020
Response inhibition has previously been suggested as an endophenotype for obsessive–compulsive disorder (OCD), evidenced by studies showing worse task performance, and altered task-related activation and connectivity.
Anders Lillevik Thorsen, Stella J. de Wit, Pernille Hagland, Olga Therese Ousdal, Bjarne Hansen, Kristen Hagen, Gerd Kvale, Odile A. van den Heuvel   +7 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Ageing, plasticity, and cognitive reserve in connectionist networks [PDF]

, 2008
Neurocomputational modeling has suggested that a range of mechanisms can lead to reductions in functional plasticity across development (Thomas & Johnson, 2006).
Thomas, Michael S.C., Michael S C Thomas
core  

Ingestion of artificial sweeteners leads to caloric frustration memory in Drosophila

Nature Communications, 2017
While non-caloric artificial sweeteners (NAS) are used as food additives, it’s unclear whether animals perceive NAS as positive or negative percept. Here, Musso and colleagues show in Drosophila that NAS is a negative percept, encoded in a new type of ...
Pierre-Yves Musso, Aurélie Lampin-Saint-Amaux, Paul Tchenio, Thomas Preat   +3 more
doaj   +1 more source

Cortical priming strategies for gait training after stroke: a controlled, stratified trial

Journal of NeuroEngineering and Rehabilitation, 2020
Background Stroke survivors experience chronic gait impairments, so rehabilitation has focused on restoring ambulatory capacity. High-intensity speed-based treadmill training (HISTT) is one form of walking rehabilitation that can improve walking, but its
Sangeetha Madhavan, Brice T. Cleland, Anjali Sivaramakrishnan, Sally Freels, Hyosok Lim, Fernando D. Testai, Daniel M. Corcos   +6 more
doaj   +1 more source

The Role of Early Growth Response 1 (EGR1) in Brain Plasticity and Neuropsychiatric Disorders

Frontiers in Behavioral Neuroscience, 2017
It is now clearly established that complex interactions between genes and environment are involved in multiple aspects of neuropsychiatric disorders, from determining an individual’s vulnerability to onset, to influencing its response to therapeutic ...
Florian Duclot, M. Kabbaj
semanticscholar   +1 more source