Results 91 to 100 of about 195,791 (228)

Identifying tumor type and cell type-specific gene expression alterations in pediatric central nervous system tumors

Nature Communications
Central nervous system (CNS) tumors are the leading cause of pediatric cancer death, and these patients have an increased risk for developing secondary neoplasms.
Min Kyung Lee, Nasim Azizgolshani, Joshua A. Shapiro, Lananh N. Nguyen, Fred W. Kolling, George J. Zanazzi, Hildreth Robert Frost, Brock C. Christensen   +7 more
doaj   +1 more source

Evaluation of a Novel Approach for Automatic Volume Determination of Glioblastomas Based on Several Manual Expert Segmentations [PDF]

arXiv, 2011
The glioblastoma multiforme is the most common malignant primary brain tumor and is one of the highest malignant human neoplasms. During the course of disease, the evaluation of tumor volume is an essential part of the clinical follow-up. However, manual segmentation for acquisition of tumor volume is a time-consuming process.
arxiv  

Brain organoids and insights on human evolution. [PDF]

, 2019
Human brain organoids, generated from pluripotent stem cells, have emerged as a promising technique for modeling early stages of human neurodevelopment in controlled laboratory conditions.
Muotri, Alysson R
core  

Serum microRNA array analysis identifies miR-140-3p, miR-33b-3p and miR-671-3p as potential osteoarthritis biomarkers involved in metabolic processes. [PDF]

, 2017
Background: MicroRNAs (miRNAs) in circulation have emerged as promising biomarkers. In this study, we aimed to identify a circulating miRNA signature for osteoarthritis (OA) patients and in combination with bioinformatics analysis to evaluate the utility
A Brazma, A Nan, A Okuhara, A Turchinovich, B Aryal, B Mayr, B Sharif, B Zhang, BM Bolstad, BM Kuhn, BM Mayr, C Beyer, C Chen, C Guay, C Taurino, CL Andersen, D Dlouha, D Iliopoulos, D Zhang, DT Felson, F Kostopoulou, FE Nicolas, G Dennis Jr, G Li, G Tardif, GD Miles, GR Sondag, GS Lien, H Causton, JB van Meurs, JD Storey, JD Storey, KC Vickers, L Qi, M Cross, M Parrizas, MB Goldring, MC Hochberg, MD Paraskevopoulou, MP Gantier, OF Laterza, Q Zhuo, R Gernapudi, RF Loeser, RI Gregory, S Kluzek, S Kumar, S Miyaki, T Thomou, TA Karlsen, VM Borgonio Cuadra, W Cleveland, WM Reichmann, X Chen, X Chen, X Tan, X Wang, Y Klipper-Aurbach, Y Zhang, YH Li   +59 more
core   +1 more source

Global and regional brain metabolic scaling and its functional consequences [PDF]

BMC Biology 5:18 (2007), 2007
Background: Information processing in the brain requires large amounts of metabolic energy, the spatial distribution of which is highly heterogeneous reflecting complex activity patterns in the mammalian brain. Results: Here, it is found based on empirical data that, despite this heterogeneity, the volume-specific cerebral glucose metabolic rate of ...
arxiv  

Self\u2010esteem and academic difficulties in preadolescents and adolescents healed from paediatric leukaemia [PDF]

, 2017
Adolescents with cancer may demonstrate problems in their self\u2010esteem and schooling. This study aims to screen the preadolescents and adolescents more at risk in their self\u2010esteem perception and schooling difficulties post\u2010five years from ...
Basso, Giuseppe, Bonichini, Sabrina, Pillon, Marta, Taverna, Livia, Tremolada, Marta   +4 more
core   +1 more source

Focal Spot, Fall/Winter 2002/2003 [PDF]

, 2003
https://digitalcommons.wustl.edu/focal_spot_archives/1092/thumbnail ...

core   +1 more source

Subtotal resection of vestibular schwannoma: evaluation with Ki-67 measurement, magnetic resonance imaging, and long-term observation [PDF]

, 2017
Purpose The aim of this study was to compare the postoperative clinical and radiological data of patients with vestibular schwannomas who were initially managed by near total resection (NTR) or subtotal resection (STR).
Angeletti, Diletta, Carletti, Raffaella, De Vincentiis, Marco, Di Gioia, Cira Rosaria Tiziana, Iannella, Giannicola, Magliulo, Giuseppe, Manno, Alessandra, Pasquariello, Benedetta, Savastano, Ersilia   +8 more
core   +1 more source

Identification of epidermal Pdx1 expression discloses different roles of Notch1 and Notch2 in murine KrasG12D-induced skin carcinogenesis in vivo [PDF]

, 2010
Background The Ras and Notch signaling pathways are frequently activated during development to control many diverse cellular processes and are often dysregulated during tumorigenesis.
Barbara M. Grüner, Bence Sipos, Freddy Radtke, Hassan Nakhai, Jens T. Siveke, Joseph Alan Bauer, Lothar J. Strobl, Pawel K. Mazur, Roland M. Schmid, Ursula Zimber-Strobl   +9 more
core   +4 more sources

Hypoxic Cell Waves around Necrotic Cores in Glioblastoma: A Biomathematical Model and its Therapeutic Implications

, 2012
Glioblastoma is a rapidly evolving high-grade astrocytoma that is distinguished pathologically from lower grade gliomas by the presence of necrosis and microvascular hiperplasia.
Calvo, Gabriel F., Martínez-González, Alicia, Pérez-García, Víctor M., Romasanta, Luis A. Pérez   +3 more
core   +1 more source