Results 41 to 50 of about 1,109,078 (325)

Glutamate-mediated blood-brain barrier opening. implications for neuroprotection and drug delivery [PDF]

, 2016
The blood-brain barrier is a highly selective anatomical and functional interface allowing a unique environment for neuro-glia networks. Blood-brain barrier dysfunction is common in most brain disorders and is associated with disease course and delayed ...
CECCANTI , MARCO, Chassidim, Y, COLONNESE, Claudio, D'ELIA, ALESSANDRO, Fassler, M, Friedman, A., INGHILLERI, Maurizio, Nucciarelli, V, ONESTI, EMANUELA, Pell, Gs, Prager, O, Raccah, R, Roth, Y, SALVATI, Maurizio, SANTORO, Antonio, Shahar, H, Vazana, U, Veksler, R, Zangen, A   +18 more
core   +1 more source

Gamma‐induction in frontotemporal dementia (GIFTeD) randomized placebo‐controlled trial: Rationale, noninvasive brain stimulation protocol, and study design

Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 2021
Introduction Frontotemporal dementia (FTD) is a neurodegenerative disorder for which there is no effective pharmacological treatment. Recently, interneuron activity responsible for fast oscillatory brain activity has been found to be impaired in a mouse ...
Martina Assogna, Giulia Sprugnoli, Daniel Press, Brad Dickerson, Joanna Macone, Sonia Bonnì, Ilaria Borghi, Ann Connor, Megan Hoffman, Nainika Grover, Bonnie Wong, Changyu Shen, Alessandro Martorana, Molly O'Reilly, Giulio Ruffini, Georges El Fakhri, Giacomo Koch, Emiliano Santarnecchi   +17 more
doaj   +1 more source

Towards a computational model for stimulation of the Pedunculopontine nucleus [PDF]

, 2009
The pedunculopontine nucleus (PPN) has recently been suggested as a new therapeutic target for deep brain stimulation (DBS) in patients suffering from Parkinson's disease, particularly those with severe gait and postural impairment [1].
Gils, Stephan A. van, Heida, Tjitske, Lourens, Marcel A.J., Meijer, Hil G.E.   +3 more
core   +3 more sources

Using transcranial direct-current stimulation (tDCS) to understand cognitive processing [PDF]

, 2016
Noninvasive brain stimulation methods are becoming increasingly common tools in the kit of the cognitive scientist. In particular, transcranial direct-current stimulation (tDCS) is showing great promise as a tool to causally manipulate the brain and ...
Cosman, Josh D., Fukuda, Keisuke, Reinhart, Robert M.G., Woodman, Geoffrey F.   +3 more
core   +1 more source

Lasting EEG/MEG aftereffects on human brain oscillations after rhythmic transcranial brain stimulation: Level of control over oscillatory network activity [PDF]

, 2015
A number of rhythmic protocols have emerged for non-invasive brain stimulation (NIBS) in humans, including transcranial alternating current stimulation (tACS), oscillatory transcranial direct current stimulation (otDCS) and repetitive (also called ...
Gross, Joachim, Thut, Gregor, Veniero, Domenica, Vossen, Alexandra   +3 more
core   +2 more sources

Neuronavigated Right Orbitofrontal 20 Hz Theta Burst Transcranial Magnetic Stimulation Augmentation for Obsessive–Compulsive Disorder with Comorbid Depression and Anxiety Disorders: An Open-Label Study

Brain Sciences
Background: Despite the availability of pharmacotherapy and psychotherapy for treating obsessive–compulsive disorder (OCD), alternative approaches need to be explored due to the high likelihood of treatment resistance.
William F. Stubbeman, Jennifer Yang, Julianne Converse, Melodi Gencosmanoglu, Daisy Morales Ortega, Jordyn Morris, Andrew Sobocinski, Vicky Li, Gabriella Gunawardane, Yana Edelen, Raya Khairkhah, Jillian Perez   +11 more
doaj   +1 more source

Neural correlates of subjective timing precision and confidence [PDF]

, 2020
Humans perceptual judgments are imprecise, as repeated exposures to the same physical stimulation (e.g. audio-visual inputs separated by a constant temporal offset) can result in different decisions. Moreover, there can be marked individual differences –
Arnold, D. H., Hohaia, W., Yarrow, K.
core   +1 more source

Association between cognitive performance and cortical glucose metabolism in patients with mild Alzheimer's disease [PDF]

, 2005
Background: Neuronal and synaptic function in Alzheimer's disease (AD) is measured in vivo by glucose metabolism using positron emission tomography (PET). Objective: We hypothesized that neuronal activation as measured by PET is a more sensitive index of
A. Drzezga, A.L.W. Bokde, Baron JC, C. Born, Collins DL, G. Leinsinger, H. Hampel, H.-J. Moeller, Herholz K, Herscovitch P, Ibanez V, Ishii K, J. Thissen, Jueptner M, M. Schwaiger, McKhann G, Meltzer CC, Meltzer CC, Mentis MJ, Mentis MJ, P. Bartenstein, Pietrini P, Pietrini P, Pietrini P, Rapoport SI, S.J. Teipel, Sokoloff L, W. Dong   +27 more
core   +1 more source

A two-site, open-label, non-randomized trial comparing Focal Electrically-Administered Seizure Therapy (FEAST) and right unilateral ultrabrief pulse electroconvulsive therapy (RUL-UBP ECT)

Brain Stimulation, 2020
Background: Focal Electrically-Administered Seizure Therapy (FEAST) is a form of electroconvulsive therapy (ECT) that spatially focuses the electrical stimulus to initiate seizure activity in right prefrontal cortex.
Gregory L. Sahlem, William V. McCall, E. Baron Short, Peter B. Rosenquist, James B. Fox, Nagy A. Youssef, Andrew J. Manett, Suzanne E. Kerns, Morgan M. Dancy, Laryssa McCloud, Mark S. George, Harold A. Sackeim   +11 more
doaj   +1 more source

A pilot randomized controlled trial of supervised, at-home, self-administered transcutaneous auricular vagus nerve stimulation (taVNS) to manage long COVID symptoms

Bioelectronic Medicine, 2022
Background Although the coronavirus disease 19 (COVID-19) pandemic has now impacted the world for over two years, the persistent secondary neuropsychiatric effects are still not fully understood.
Bashar W. Badran, Sarah M. Huffman, Morgan Dancy, Christopher W. Austelle, Marom Bikson, Steven A. Kautz, Mark S. George   +6 more
doaj   +1 more source