Results 51 to 60 of about 1,087,620 (371)

Gamma‐induction in frontotemporal dementia (GIFTeD) randomized placebo‐controlled trial: Rationale, noninvasive brain stimulation protocol, and study design

Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 2021
Introduction Frontotemporal dementia (FTD) is a neurodegenerative disorder for which there is no effective pharmacological treatment. Recently, interneuron activity responsible for fast oscillatory brain activity has been found to be impaired in a mouse ...
Martina Assogna, Giulia Sprugnoli, Daniel Press, Brad Dickerson, Joanna Macone, Sonia Bonnì, Ilaria Borghi, Ann Connor, Megan Hoffman, Nainika Grover, Bonnie Wong, Changyu Shen, Alessandro Martorana, Molly O'Reilly, Giulio Ruffini, Georges El Fakhri, Giacomo Koch, Emiliano Santarnecchi   +17 more
doaj   +1 more source

Transcranial Direct Current Stimulation Effects on the Neural Substrate of Conceptual Representations

Brain Sciences, 2023
The aim of this study was to shed light on the neural substrate of conceptual representations starting from the construct of higher-order convergence zones and trying to evaluate the unitary or non-unitary nature of this construct.
Sonia Bonnì, Ilaria Borghi, Michele Maiella, Elias Paolo Casula, Giacomo Koch, Carlo Caltagirone, Guido Gainotti   +6 more
doaj   +1 more source

Relations between large scale brain connectivity and effects of regional stimulation depend on collective dynamical state [PDF]

PLoS Computational Biology, 16-9 (2020), 2020
At the macroscale, the brain operates as a network of interconnected neuronal populations, which display rhythmic dynamics that support interareal communication. Understanding how stimulation of a particular brain area impacts such concerted activity is important for gaining basic insights into brain function and for developing neuromodulation as a ...
arxiv   +1 more source

Optogenetics and deep brain stimulation neurotechnologies [PDF]

, 2015
Brain neural network is composed of densely packed, intricately wired neurons whose activity patterns ultimately give rise to every behavior, thought, or emotion that we experience. Over the past decade, a novel neurotechnique, optogenetics that combines
A Berndt, A Berndt, A Priori, AA Kuhn, AA Kuhn, AS Chuong, B Sauer, B Wingeier, BY Chow, BY Chow, C Bamann, D Luo, D Oesterhelt, D Oesterhelt, D Williams, ES Boyden, EY Uc, F Zhang, F Zhang, G Foffani, G Miesenbock, G Nagel, J Cavanaugh, J Mobley, J Volkmann, J Wells, J Wietek, JG Bernstein, JG Bernstein, JG Bernstein, JL Spudich, JL Spudich, JO Dostrovsky, JZ Tsien, L Bekar, L Madisen, LA Gunaydin, M Weinberger, M Weinberger, MC Rodriguez-Oroz, MJ Lehmkuhle, ML Welter, MM Doroudchi, O Yizhar, P Brown, P Silberstein, R Levy, R Levy, R Levy, R Waehler, S Zhao, TW Chen, VC Anderson, X Han, X Han, X Han, X Han, X Han, X Liu   +58 more
core   +2 more sources

Neuronavigated Right Orbitofrontal 20 Hz Theta Burst Transcranial Magnetic Stimulation Augmentation for Obsessive–Compulsive Disorder with Comorbid Depression and Anxiety Disorders: An Open-Label Study

Brain Sciences
Background: Despite the availability of pharmacotherapy and psychotherapy for treating obsessive–compulsive disorder (OCD), alternative approaches need to be explored due to the high likelihood of treatment resistance.
William F. Stubbeman, Jennifer Yang, Julianne Converse, Melodi Gencosmanoglu, Daisy Morales Ortega, Jordyn Morris, Andrew Sobocinski, Vicky Li, Gabriella Gunawardane, Yana Edelen, Raya Khairkhah, Jillian Perez   +11 more
doaj   +1 more source

Causal evidence that intrinsic beta frequency is relevant for enhanced signal propagation in the motor system as shown through rhythmic TMS [PDF]

, 2016
Correlative evidence provides support for the idea that brain oscillations underpin neural computations. Recent work using rhythmic stimulation techniques in humans provide causal evidence but the interactions of these external signals with intrinsic ...
Akam, Bauer, Blankenship, Brittain, Brittain, Brown, Cecere, Chanes, de Graaf, Di Lazzaro, Edden, Engel, Feurra, Gregor Thut, Guderian, Hanslmayr, Hari, Helfrich, Jaegle, Jensen, Jensen, Jensen, Jon Driver, Joseph L. Brooks, Joundi, Jung, Klimesch, Klimesch, Lakatos, Lakatos, Lee, Little, Litvak, Marcos Economides, Markus Bauer, Mathewson, McClelland, Mima, Mima, Mima, Muthukumaraswamy, Neuling, Nunez, Oostenveld, Pfurtscheller, Pogosyan, Romei, Romei, Romei, Rosa, Rossi, Rossini, Ruzzoli, Salinas, Sauseng, Schoffelen, Skaggs, Strüber, Sven Bestmann, Thut, Thut, van Pelt, Veniero, Vincenzo Romei, Wallstrom, Will Penny, Womelsdorf, Yousry   +67 more
core   +6 more sources

A pilot randomized controlled trial of supervised, at-home, self-administered transcutaneous auricular vagus nerve stimulation (taVNS) to manage long COVID symptoms

Bioelectronic Medicine, 2022
Background Although the coronavirus disease 19 (COVID-19) pandemic has now impacted the world for over two years, the persistent secondary neuropsychiatric effects are still not fully understood.
Bashar W. Badran, Sarah M. Huffman, Morgan Dancy, Christopher W. Austelle, Marom Bikson, Steven A. Kautz, Mark S. George   +6 more
doaj   +1 more source

Completing the puzzle: why studies in non-human primates are needed to better understand the effects of non-invasive brain stimulation [PDF]

arXiv, 2021
Brain stimulation is a core method in neuroscience. Numerous non-invasive brain stimulation (NIBS) techniques are currently in use in basic and clinical research, and recent advances promise the ability to non-invasively access deep brain structures. While encouraging, there is a surprising gap in our understanding of precisely how NIBS perturbs neural
arxiv  

Deep brain and cortical stimulation for epilepsy [PDF]

, 2014
Background : Despite optimal medical treatment, including epilepsy surgery, many epilepsy patients have uncontrolled seizures. In the last decades, interest has grown in invasive intracranial neurostimulation as a treatment for these patients ...
Anderson, Andrade, Becker, Beyenburg, Boon, Borghs, Boëx, Buren, Chabardes, Chkhenkeli, Cramer, Cramer, Curtin, Deeks, Devinsky, Elbourne, Elisevich, Engel, Fisher, Fisher, Fisher, Forsgren, Franzini, Handforth, Hodaie, Jehi, Katariwala, Kellinghaus, Khan, Kwan, Kwan, Kwan, Lim, Lim, McLachlan, Morrell, Neligan, Parrent, Privitera, Raftopoulos, Raftopoulos, Rijckevorsel, Rijckevorsel, Salanova, Schulze-Bonhage, Schulze-Bonhage, Selwa, Stedman, Tellez-Zenteno, Tellez-Zenteno, Tisi, Tomson, Valentin, Velasco, Velasco, Velasco, Velasco, Velasco, Velasco, Vonck, Wiebe, Wille, Wright, Zou   +63 more
core   +1 more source

Glutamate-mediated blood-brain barrier opening. implications for neuroprotection and drug delivery [PDF]

, 2016
The blood-brain barrier is a highly selective anatomical and functional interface allowing a unique environment for neuro-glia networks. Blood-brain barrier dysfunction is common in most brain disorders and is associated with disease course and delayed ...
CECCANTI , MARCO, Chassidim, Y, COLONNESE, Claudio, D'ELIA, ALESSANDRO, Fassler, M, Friedman, A., INGHILLERI, Maurizio, Nucciarelli, V, ONESTI, EMANUELA, Pell, Gs, Prager, O, Raccah, R, Roth, Y, SALVATI, Maurizio, SANTORO, Antonio, Shahar, H, Vazana, U, Veksler, R, Zangen, A   +18 more
core   +1 more source