Results 71 to 80 of about 1,142,672 (327)

Early differences in lassitude predicts outcomes in Stanford Neuromodulation Therapy for difficult to treat depression

open access: yesnpj Mental Health Research
Stanford Neuromodulation Therapy (SNT), has recently shown rapid efficacy in difficult to treat (DTT) depression. We conducted an exploratory analysis of individual symptom improvements during treatment, correlated with fMRI, to investigate this rapid ...
David Benrimoh   +9 more
doaj   +1 more source

Totally Implantable Bidirectional Neural Prostheses: A Flexible Platform for Innovation in Neuromodulation. [PDF]

open access: yes, 2018
Implantable neural prostheses are in widespread use for treating a variety of brain disorders. Until recently, most implantable brain devices have been unidirectional, either delivering neurostimulation without brain sensing, or sensing brain activity to
Starr, Philip A
core   +2 more sources

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Distinct patterns of temporal and directional connectivity among intrinsic networks in the human brain [PDF]

open access: yes, 2017
To determine the spatiotemporal relationships among intrinsic networks of the human brain, we recruited seven neurosurgical patients (four males and three females) who were implanted with intracranial depth electrodes.
Bickel, Stephan   +9 more
core   +2 more sources

Neural correlates of subjective timing precision and confidence [PDF]

open access: yes, 2020
Humans perceptual judgments are imprecise, as repeated exposures to the same physical stimulation (e.g. audio-visual inputs separated by a constant temporal offset) can result in different decisions. Moreover, there can be marked individual differences –
Arnold, D. H., Hohaia, W., Yarrow, K.
core   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

open access: yesFEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Inhibit My Disinhibition: The Role of the Inferior Frontal Cortex in Sexual Inhibition and the Modulatory Influence of Sexual Excitation Proneness

open access: yesFrontiers in Human Neuroscience, 2018
Sexual behaviour is the result of an interplay between distinct neural inhibitory and excitatory mechanisms. Individual differences in sexual excitation and sexual inhibition are proposed to play an important role in the processes sustaining the ...
Geraldine Rodriguez   +3 more
doaj   +1 more source

Setting reference level in the human safety guidelines via nerve activation intercomparison at IF [PDF]

open access: yes, 2019
International guidelines/standards have been published for human protection from electromagnetic field exposure. The research in the intermediate frequencies (IF: 300 Hz-10 MHz) is scattered unlike for other frequencies, and thus the limit prescribed in ...
Gomez-Tames, Jose   +7 more
core   +2 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Using Remotely Supervised At-Home TES for Enhancing Mental Resilience

open access: yesFrontiers in Human Neuroscience, 2022
We are in the midst of a mental health crisis with major depressive disorder being the most prevalent among mental health disorders and up to 30% of patients not responding to first-line treatments.
Jasmina Paneva   +16 more
doaj   +1 more source

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