Results 91 to 100 of about 6,149,012 (253)

Glutamine Metabolism in Brain Tumors

Cancers, 2019
Altered metabolism is a hallmark of cancer cells. Tumor cells rewire their metabolism to support their uncontrolled proliferation by taking up nutrients from the microenvironment.
Sivaraman Natarajan, S. Venneti
semanticscholar   +1 more source

Colony stimulating factor-1 receptor as a treatment for cognitive deficits postfractionated whole-brain irradiation. [PDF]

, 2017
Whole-brain irradiation (WBI) is commonly used to treat primary tumors of the central nervous systems tumors as well as brain metastases. While this technique has increased survival among brain tumor patients, the side effects of including a decline in ...
Rosi, Susanna
core   +2 more sources

Towards Immunotherapy for Pediatric Brain Tumors.

Trends in immunology, 2019
Pediatric brain tumors are the leading cause of childhood cancer-related death. Immunotherapy is a powerful new approach for treating some refractory cancers; applying this 'fourth pillar' of cancer treatment to pediatric brain tumors is an exciting but ...
S. S. Wang, P. Bandopadhayay, Misty R. Jenkins   +2 more
semanticscholar   +1 more source

Functional analysis of telomere maintenance mechanisms is more informative than immunohistochemistry for ATRX mutation interpretation in Gliomas

Acta Neuropathologica Communications
Loss of ATRX function, a diagnostic criterion of IDH-mutant astrocytoma, is closely associated with alternative lengthening of telomeres (ALT), a telomere maintenance mechanism (TMM).
Clemence Guerriau, Camille Léonce, Catherine Carpentier, Karima Mokhtari, Franck Bielle, Amel Dridi-Aloulou, Patrick Lomonte, David Meyronet, Marc Sanson, Luis Castro-Vega, Delphine Aude Poncet   +10 more
doaj   +1 more source

YB-1 dependent oncolytic adenovirus efficiently inhibits tumor growth of glioma cancer stem like cells [PDF]

, 2013
Background: The brain cancer stem cell (CSC) model describes a small subset of glioma cells as being responsible for tumor initiation, conferring therapy resistance and tumor recurrence.
Beier, Dagmar, Girbinger, Vroni, Holm, Per Sonne, Lage, Hermann, Mantwill, Klaus, Mittelbronn, Michel Guy André, Naumann, Ulrike, Schlegel, Jürgen, Seznec, Janina, Surowiak, Pawel   +9 more
core   +1 more source

Anomalous vascularization in a Wnt medulloblastoma: A case report [PDF]

, 2016
BACKGROUND: Medulloblastoma is the most common malignant brain tumor in children. To date only few cases of medulloblastoma with hemorrhages have been reported in the literature.
Cacchione, Antonella, Carai, Andrea, Colafati, Giovanna Stefania, Dell'Anna, Vito Andrea, Di Giannatale, Angela, Diomedi Camassei, Francesca, Ferretti, Elisabetta, Locatelli, Franco, Marrazzo, Antonio, Mastronuzzi, Angela, Miele, Evelina, Po, Agnese   +11 more
core   +2 more sources

Pseudoprogression of brain tumors

Journal of Magnetic Resonance Imaging, 2018
This review describes the definition, incidence, clinical implications, and magnetic resonance imaging (MRI) findings of pseudoprogression of brain tumors, in particular, but not limited to, high‐grade glioma.
S. Thust, M. J. van den Bent, M. Smits
semanticscholar   +1 more source

Polyclonal expansion of functional tumor-reactive lymphocytes infiltrating glioblastoma for personalized cell therapy

Nature Communications
Tumor-infiltrating lymphocyte (TIL)-therapy has received FDA approval for the treatment of advanced melanoma and shows potential for broader applications in solid tumors, including glioblastoma.
Martina Maffezzini, Silvia Musio, Natalia Di Ianni, Agnese Rumolo, Monica Patanè, Andrea Galluzzo, Irene Sambruni, Arianna Berlendis, Domenico Aquino, Giacomo Baso, Manuela Zingarelli, Manuel Facciolla, Luisa Maddaloni, Rossella Valentino, Rosina Paterra, Fabio Agistri, Mariangela Farinotti, Luca Mattei, Paola Coluccia, Francesco Acerbi, Francesco DiMeco, Bianca Pollo, Antonio Silvani, Marica Eoli, Catia Traversari, Daniela Montagna, Serena Pellegatta   +26 more
doaj   +1 more source

Spider venom administration impairs glioblastoma growth and modulates immune response in a non-clinical model. [PDF]

, 2020
Molecules from animal venoms are promising candidates for the development of new drugs. Previous in vitro studies have shown that the venom of the spider Phoneutria nigriventer (PnV) is a potential source of antineoplastic components with activity in ...
Barreto, Natália, Bonfanti, Amanda Pires, Brunetto, Sérgio, Caballero, Marcus, Cordeiro, Gabriel, Moura, Fernanda, Munhoz, Jaqueline, Ramos, Celso Dario, Rapôso, Catarina, Rocha-E-Silva, Thomaz, Sutti, Rafael, Thome, Rodolfo, Verinaud, Liana   +12 more
core   +1 more source

Registration of brain tumor images using hyper-elastic regularization [PDF]

, 2012
In this paper, we present a method to estimate a deformation field between two instances of a brain volume having tumor. The novelties include the assessment of the disease progress by observing the healthy tissue deformation and usage of the Neo ...
Hamamci, Andac, Hamamcı, Andaç, Unal, Gozde, Ünal, Gözde   +3 more
core   +1 more source