Results 51 to 60 of about 289,150 (274)

Is there an integrative center in the vertebrate brain-stem? A robotic evaluation of a model of the reticular formation viewed as an action selection device [PDF]

, 2005
Neurobehavioral data from intact, decerebrate, and neonatal rats, suggests that the reticular formation provides a brainstem substrate for action selection in the vertebrate central nervous system.
Baerends, G., Barto, A., Blumberg, B., Bowsher, D., Cherniak, C., Delwaide, P., Humphries, M., Jones, B., Kevin Gurney, Maes, P., Mark D. Humphries, Montes-Gonzalez, F., Newman, D., Scheibel, M., Stevens, D., Tony J. Prescott   +15 more
core   +2 more sources

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Six weeks that changed the preterm infant brain: lessons learned from the Family Nurture Intervention randomized controlled trials

Frontiers in Psychology
AimWe review extensive results from two randomized controlled trials conducted over 9 years, comparing standard care (SC) in level-4 neonatal intensive care units (NICUs) with SC plus Family Nurture Intervention (FNI).MethodsFNI included ~six weeks of ...
Robert J. Ludwig, Robert J. Ludwig, Michael M. Myers, Michael M. Myers, Martha G. Welch, Martha G. Welch   +5 more
doaj   +1 more source

Evolution and physiology of neural oxygen sensing

Frontiers in Physiology, 2014
Major evolutionary trends in animal physiology have been heavily influenced by atmospheric O2 levels. Amongst other important factors, the increase in atmospheric O2 which occurred in the Pre-Cambrian and the development of aerobic respiration beckoned ...
Kauê Machado Costa, Daniela eAccorsi-Mendonça, Davi J.A. Moraes, Benedito H Machado   +3 more
doaj   +1 more source

Microsurgery vs. Gamma Knife Radiosurgery for the Treatment of Brainstem Cavernous Malformations: A Systematic Review and Meta-Analysis

Frontiers in Neurology, 2021
Background: Brainstem cavernous malformations (BSCMs) are a subset of cerebral cavernous malformations with precarious locations and potentially devastating clinical courses.
Xiangyu Gao, Kangyi Yue, Jidong Sun, Yuan Cao, Boyan Zhao, Haofuzi Zhang, Shuhui Dai, Lei Zhang, Peng Luo, Xiaofan Jiang   +9 more
doaj   +1 more source

Bedside differentiation of vestibular neuritis from central "vestibular pseudoneuritis". [PDF]

, 2008
Acute unilateral peripheral and central vestibular lesions can cause similar signs and symptoms, but they require different diagnostics and management.
Brandt, Thomas, Cnyrim, C. D., Karch, C., Newman-Toker, D., Strupp, Michael   +4 more
core   +1 more source

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source

Linoleic acid participates in the response to ischemic brain injury through oxidized metabolites that regulate neurotransmission. [PDF]

, 2017
Linoleic acid (LA; 18:2 n-6), the most abundant polyunsaturated fatty acid in the US diet, is a precursor to oxidized metabolites that have unknown roles in the brain.
Bazinet, Richard P, Hammock, Bruce D, Hennebelle, Marie, Kitson, Alex P, Lee, Kin Sing Stephen, Metherel, Adam H, Otoki, Yurika, Richardson, Christine E, Taha, Ameer Y, Yang, Jun, Zhang, Liang, Zhang, Zhichao   +11 more
core   +1 more source

Acoustic Measures Capture Speech Dysfunction in Spinocerebellar Ataxia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxias (SCA) are hereditary cerebellar degenerative disorders with a common feature of dysarthria, involving impaired phonatory and articulatory control of speech, thereby affecting social communication. In this study, we investigated whether acoustic measures could objectively measure speech dysfunction and identify
Zena Fadel, Charlotte Hennessey, Hannah Lee, Pia Parekh, Sheng‐Han Kuo, Ami Kumar   +5 more
wiley   +1 more source

Arousal system stimulation and anesthetic state alter visuoparietal connectivity

Frontiers in Systems Neuroscience, 2023
Cortical information processing is under the precise control of the ascending arousal system (AAS). Anesthesia suppresses cortical arousal that can be mitigated by exogenous stimulation of the AAS. The question remains to what extent cortical information
Axel Hutt, Anthony G. Hudetz
doaj   +1 more source