Results 71 to 80 of about 36,496 (307)

Time/frequency analysis of contact-friction instabilities. Application to automotive brake squeal. [PDF]

open access: yes, 2010
Robust design of silent brakes is a current industrial challenge. Braking systems enter in the more general context of unstable systems featuring contact friction interaction.
BALMES, Etienne   +3 more
core   +2 more sources

A study of commercial vehicle brake judder transmission using multi-body dynamic analysis [PDF]

open access: yes, 2007
YesBraking-induced forced vibration, known as brake judder in road vehicles, causes dissatisfaction to drivers and passengers and also damage and possible early failure in components and systems. In this paper, the transmission of judder vibration from
Day, Andrew J.   +2 more
core   +1 more source

ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology

open access: yesAdvanced Science, EarlyView.
This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li   +25 more
wiley   +1 more source

Dual output variable pitch turbofan actuation system [PDF]

open access: yes, 1976
An improved actuating mechanism was provided for a gas turbine engine incorporating fan blades of the variable pitch variety, the actuator adapted to rotate the individual fan blades within apertures in an associated fan disc. The actuator included means
Broman, C. L., Griswold, R. H., Jr.
core   +1 more source

SAA/FPR2 Signaling Between Pericentral Hepatocytes and Macrophages Exacerbates Zonated Liver Transplant Injury

open access: yesAdvanced Science, EarlyView.
After liver transplantation, ischemia‐reperfusion injury is more severe in pericentral regions. Multiomic analyses of human grafts and mouse models identify FOXO1 activation in pericentral hepatocytes as an upstream driver of SAA secretion. SAA recruits and activates FPR2+ macrophages, amplifying local inflammation. Amilo‐5MER inhibits SAA bioactivity,
Feng Zhang   +19 more
wiley   +1 more source

Effect of Temperature Variations on Brake Squeal Characteristics in Disc Brake Systems

open access: yesEngineering Proceedings
Brake squeal is an undesirable high-frequency noise caused by vibrations induced by friction in disc brake systems. The noise is strongly affected by temperature, as this influences the material properties of the friction pair and the dynamic behaviour ...
Akif Yavuz   +3 more
doaj   +1 more source

Defining the Temperature Change of the Brake Disc

open access: yesActa Technica Jaurinensis, 2018
In the article the thermal analysis of the brake disc and separator disc of a high performance power machine will be presented. As example an agricultural vehicle with weight of 30000 kg and maximum travel speed of 40 km/h will be taken.
Melinda Menyhártné Baracskai
doaj   +1 more source

S100A14 in Tumor‐Derived EVs Targets PIAS3 to Reprogram Astrocytes and Induce Immunosuppressive Microenvironment Promoting Brain Metastasis and Germacrone Reversal Effect

open access: yesAdvanced Science, EarlyView.
This study identifies S100A14 in tumor‐derived exosomes as a key driver of brain metastasis. S100A14 targets PIAS3 in astrocytes, activating STAT3 signaling and promoting immunosuppressive MDSCs recruitment via chemokine secretion. Germacrone, a natural compound, binds S100A14 to disrupt this axis, effectively inhibiting brain metastasis with low ...
Qian Feng   +13 more
wiley   +1 more source

Full-Scale Simulation and Experimental Study of Heat Transfer in Landing Gear Brake Discs for Medium-Sized Passenger Aircraft

open access: yesApplied Sciences
Aircraft brake discs undergo rapid temperature rises during braking, critically impacting safety, lifespan, and adjacent components. Therefore, it is particularly important to study the heat transfer mechanism during the braking process and predict the ...
Qingtang Meng   +3 more
doaj   +1 more source

Characterization of surface morphology and its correlation with friction performance of brake pads [PDF]

open access: yes, 2015
The present work presents the morphology evolution of a brake material surface submitted to braking tests through a laboratory-scale tribometer. Optical microscope images of the material’s surface were obtained for every 10 braking operations.
Ando, Matyas   +6 more
core   +2 more sources

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