Results 61 to 70 of about 2,242 (266)
Advanced Science, EarlyView.TGFBI deficiency elevates O‐GlcNAcylation, promoting the transcriptional activation of ADAMTS16 and OGT‐mediated post‐translational modification of ADAMTS16 at Ser1170. This leads to its stabilization and accumulation, driving chondrocyte metabolic disorders and senescent phenotypes, ultimately resulting in fibrocartilage dysfunction and TMJOA ...
Xin Liu +12 more
wiley +1 more source
Temperature Field and Thermal Stress Analysis of ULF Light Rail Trains Brake Disc
机车电传动, 2018 To research the distribution of temperature filed and the thermal stress of ULF light rail trains, the three-dimensional finite element model was constructed, and according to apply proper boundary condition to the brake disc , the heat flux generation ...
DAI Xinliang, WANG Boming
doaj
Advanced Science, EarlyView.A carrier‐free zinc‐coordinated polyphenol nanoplatform (ZnCA NPs) is designed as an “all‐in‐one” therapeutic strategy for intestinal inflammation. The ZnCA NPs exhibit enhanced colonic accumulation and broad‐spectrum reactive oxygen and nitrogen species scavenging.
Qiwen Xie +7 more
wiley +1 more source
AtmosphereIn this paper, results are presented for an on-road measurement campaign for measuring the brake wear particles of disc brakes on a heavy-duty tractor trailer during the EU P012101 Pilot Project funded by the European Parliament.
Misja Frederik Alban Steinmetz +2 more
doaj +1 more source
Neuro-genetic optimization of disc brake performance at elevated temperatures [PDF]
FME Transactions, 2014 The basic problem of automotive brakes operation is the decreasing of their performance at elevated temperatures in the contact of friction pair (brake disc and brake pad).
Ćirović Velimir +2 more
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A CASE STUDY ON THERMAL ANALYSIS OF THE DISC BRAKE USED FOR HEAVY-DUTY CARS
Platform, a Journal of Engineering, 2023 The brake system converts kinetic energy into thermal energy, resulting in a rise in the temperatures of the disc brake due to the friction caused by the pressure brake between the turntable and the brake pads. This study aimed to investigate the thermal
Said S. Al Riyami +3 more
doaj
Cannabinoid CB1 Receptor in Nociceptors Mediates Postoperative Analgesia via ASIC3 Inhibition
Advanced Science, EarlyView.CB1R and ASIC3 are co‐expressed in CGRP+ nociceptors of mouse DRG. Plantar incision triggers an upregulation of ASIC3 and activation of ASIC3+ neurons, driving mechanical allodynia. CB1R activation suppresses ASIC3 function and downstream ERK1/2 phosphorylation, thereby braking nociceptive signaling and accelerating pain resolution.
Kangtai Xu +13 more
wiley +1 more source
Research on Braking Vibration Characteristics of Grooved Brake Interface of Disc Brake
IOP Conference Series: Materials Science and Engineering, 2019 Abstract With the good performance and wide application of surface texture in various aspects, more and more scholars are devoted to investigating the effect of texture interface on tribological properties. Disc brake friction pair is a typical friction brake interface.
Zhihua Sha +6 more
openaire +1 more source
CD112 Lactylation Drives Dual Immune Evasion From CD8+ T Cells and NK Cells
Advanced Science, EarlyView.AARS2 functions as an intracellular lactate sensor and lactyltransferase, catalyzing CD112 K412 lactylation to block ubiquitination‐dependent degradation and stabilize CD112. This pathway suppresses CD8+ T‐cell and NK‐cell cytotoxicity, enabling dual immune evasion.
Zhuoshuo Xu +6 more
wiley +1 more source
Analytical Model of the Frictional Heating in a Railway Brake Disc at Single Braking with Experimental Verification. [PDF]
Materials (Basel), 2022 Topczewska K +4 more
europepmc +1 more source