Results 61 to 70 of about 4,631 (294)
Advanced Science, EarlyView.ANKS1B in the nucleus accumbens plays a critical role in the transition from controlled to escalated cocaine intake. Mechanistically, ANKS1B interacts with CBP to epigenetically suppress FoxO3 through H3K27 acetylation. The ANKS1B‐CBP‐FoxO3 signaling cascade presents a novel theraputic target for the treatment of cocaine addiction.
Liping Yang +15 more
wiley +1 more source
, 2018 Within the field of electric vehicles, the cooperative control of a dual electro-hydraulic regenerative brake system using the foot brake pedal as the sole input of driver brake requests is a challenging control problem, especially when the electro ...
Philippe Micheau +2 more
core +1 more source
Advanced Science, EarlyView.ABSTRACT The muscle capsule of Trichinella is a critical structure that impedes immune attacks and drug penetration, yet the molecular mechanisms underlying its formation remain poorly understood. Using a high‐quality super‐pangenome comprising 12 Trichinella species, we compared extensive genomic variations between encapsulating and non‐encapsulating ...
Qingbo Lv +8 more
wiley +1 more source
Jixie chuandong, 2014 In order to enhance and improve the accuracy of characteristics analysis of wet multdisc brake and avoid the local damage by high temperature and pressure on the brakes,the wet multiple of disc brake of wheel loader drive axle is considered as the ...
朱霞, 冷志杰
doaj
Advanced Science, EarlyView.Glioblastoma (GBM) exhibits RFX7 silencing via promoter hypermethylation, which downregulates PIK3IP1 to activate PI3K/AKT signaling, increase lactate accumulation, and enhance histone H4K12 lactylation. This lactylation upregulates PD‐L1/CSF1 expression and drives the immunosuppressive microenvironment formation.
Liying Han +20 more
wiley +1 more source
Generation of Nanoparticles from Friction between Railway Brake Disks and Pads
, 2016 In this study, we measured the size distribution of particles ranging in size from 5.6 to 560 nm that were emitted between brake disks and pads under various braking conditions to observe and analyze changes to the resulting particle size distribution ...
Sechan Park (2570002) +8 more
core +1 more source
Advanced Science, EarlyView.This study achieves the synergistic integration of self‐powered sensing and edge AI acceleration to establish a real‐time fault diagnosis system. The proposed TENG‐based self‐powered bearing sensor (NSE‐TBS) and FPGA‐accelerated edge AI framework fundamentally break through the inherent limitations of conventional monitoring systems, including complex ...
Kehui Zhu +7 more
wiley +1 more source
Finite Element Analysis of Magnetic Saturation of Disk-type Magnetorheological Brake
Jixie chuandong, 2016 An evaluation magnetic saturation rate is proposed due to magnetic saturation degree not clear in the magnetorheological device. The magnetic field finite element analysis of disc- type magnetorheological brake is carried out,and the simulation results ...
Qiao Zhen, Huang Jin
doaj
Advanced Science, EarlyView.SLC25A13 is identified as an immunometabolic driver of triple‐negative breast cancer that sustains ferroptosis resistance and immune evasion through a STAT3–IFI6 circuit. Pharmacologic degradation of SLC25A13 restores ferroptosis sensitivity and enhances anti‐PD‐1 efficacy, highlighting a strategy to convert immune‐cold tumors into immunotherapy ...
Yingze Zhu +8 more
wiley +1 more source
A New Model of Stopping Sight Distance of Curve Braking Based on Vehicle Dynamics
Discrete Dynamics in Nature and Society, 2016 Compared with straight-line braking, cornering brake has longer braking distance and poorer stability. Therefore, drivers are more prone to making mistakes. The braking process and the dynamics of vehicles in emergency situations on curves were analyzed.
Rong-xia Xia +4 more
doaj +1 more source