Results 81 to 90 of about 19,582 (264)

BRAKING PRECISION, THE CAR NUMBER IN THE TRAILER AND THE HUMP''S PERFORMANCE

open access: yesNauka ta progres transportu, 2009
A form of regression equations is determined, which adequately describe a correlation between the error of braking of cuts and the average speed of their collision on hump tracks, the average length of «window» and the average quantity of setting ...
V. V. Zhuravel
doaj  

Experimental research into motor vehicle oscillations in the case of changeable deceleration [PDF]

open access: yesTransport, 2005
In this paper processes of oscillation of flexible mounted and inflexible mounted masses are analysed. The tangential effect of the wheel contact with bearing surface is given, thus enabling more precise calculus of vehicle braking parameters.
R. Pečeliūnas,   +4 more
doaj  

Material‐Encoded Synchronization of Immunogenic Cell Death With Adenosine A2A Receptor Blockade Reprograms the Tumor Microenvironment

open access: yesAdvanced Science, EarlyView.
A bismuth–copper diselenide–based nanoplatform (BSCS@PHY) coordinates immunogenic cell death with local A2A receptor blockade in 4T1 tumors. Thermally triggered shell melting exposes catalytic surfaces for glutathione depletion and chemodynamic ROS generation, while co‐delivering an A2AR antagonist and yeast‐wall adjuvant to enhance dendritic‐cell ...
Xiangting Yi   +12 more
wiley   +1 more source

Influence of Longitudinal Train Dynamics on Friction Buffer Stop Performances

open access: yesDynamics
Buffer stops have always been installed on blind tracks to mitigate the hazards associated with overruns due to insufficient or wrong braking. Conventional buffer stops fixed to the rails may absorb only limited energy while Energy-Absorbing Buffers ...
Gianluca Megna   +2 more
doaj   +1 more source

PRMT5‐Dependent Stabilization of VPS34 Orchestrates Copper Trafficking to Shield Cancer Cells from Cuproptosis and Radiotherapy

open access: yesAdvanced Science, EarlyView.
Radioresistance arises partly from tumor cells evading cuproptosis via unknown defenses. This study reveals that the PRMT5‐VPS34 axis acts as a radiation‐activated anticuproptotic mechanism: PRMT5 methylates VPS34 at Arg174, recruiting USP10 to remove K48‐linked ubiquitination and prevent degradation.
Wei Chen   +17 more
wiley   +1 more source

CXCL10/SLC11A1 Axis Exacerbates Septic Liver Injury by Regulating Neutrophil Extracellular Traps Formation to Drive Macrophage Pro‑Inflammatory Polarization

open access: yesAdvanced Science, EarlyView.
In sepsis‐induced liver injury, marked neutrophil infiltration correlates with disease severity. Neutrophil SLC11A1 drives intracellular Fe2+ and ROS via the Fenton reaction, promoting NETs formation. Hepatocyte‐derived CXCL10 recruits neutrophils and activates the JAK/STAT1/SLC11A1 axis, enhancing NETs‐mediated inflammation.
Haiping Lin   +8 more
wiley   +1 more source

Membrane‐Active Peptide Protects Against Inflammation by Targeting NLRP3 Activation at the Trans‐Golgi Network

open access: yesAdvanced Science, EarlyView.
The membrane‐active peptide Pep19‐2.5 reduces harmful inflammation by blocking activation of the NLRP3 inflammasome at trans‐Golgi network membranes. By targeting key membrane interactions, Pep19‐2.5 suppresses inflammatory IL‐1β production and alleviates allergic airway inflammation in mice, leading to reduced immune cell infiltration and improved ...
Jonas Engelhardt   +16 more
wiley   +1 more source

Immediate Growth Control in Response to Boiling Histotripsy is Prognostic for Intratumoral Immune Activation

open access: yesAdvanced Science, EarlyView.
Boiling Histrotripsy (BH), a mechanical form of focused ultrasound (FUS), allows for non‐invasive and non‐ionizing tissue destruction. Utilizing a BH treatment protocol that yielded bifurcating primary tumor growth responses, we found that immediate BH‐induced tumor growth control identifies tumors with acute reductions in antigen‐presenting cells (APC)
Lydia E. Kitelinger   +8 more
wiley   +1 more source

ANALYSIS OF POSSIBILITY TO AVOID A RUNNING-DOW ACCIDENT TIMELY BRAKING [PDF]

open access: yesAvtomobilʹnyj Transport (Harʹkov), 2013
Such circumstances under which the drive can stop the vehicle by applying timely braking before reaching the pedestrian crossing or decrease the speed to the safe limit to avoid a running-down accident is considered.
Sarayev, A.
doaj  

Leading the Pack: Next‐Generation Batteries for Humanoid Robotics

open access: yesAdvanced Science, EarlyView.
Humanoid robots challenge traditional and anticipated energy technologies. Humanoid robot benchmarks of runtimes and energy demands for industry applications inform humanoid robot battery design choices at the cell level, pack level, and system level.
Matthew Bergschneider   +6 more
wiley   +1 more source

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