Results 51 to 60 of about 3,815 (260)

USING COUPLING WEIGHTS AND RATIONAL DISTRIBUTION OF BRAKE FORCES BETWEEN THE AXLES OF WHEELED VEHICLES [PDF]

open access: yesAvtomobilʹnyj Transport (Harʹkov), 2011
The dependence of the coefficient of coupling weight-axle vehicles under braking and a ra-tional distribution coefficient of braking force to the front axle on the condition of maximum coupling weight.
M. Kholodov, M. Podrigalo
doaj  

Engineered Exosomal miR‐146a‐5p Reprograms BMSC Fate and Restores Mitochondrial Homeostasis in Glucocorticoid‐Induced Osteonecrosis of Femoral Head

open access: yesAdvanced Science, EarlyView.
Exosomal miR‐146a‐5p is identified as a pivotal regulator in steroid‐induced osteonecrosis. Its reduction activates NF‐κB signaling, compromises mitophagy, and disrupts mitochondrial bioenergetics, resulting in autophagic disequilibrium. Engineered exosomes delivering miR‐146a‐5p reinstate mitochondrial function, augment oxidative phosphorylation and ...
Zehui Lv   +13 more
wiley   +1 more source

IDEAL BRAKE FORCE DISTRIBUTION BETWEEN THE AXLES OF THE TWO-AXLE VEHICLE SERVICE BRAKE APPLICATIONS [PDF]

open access: yesAvtomobilʹnyj Transport (Harʹkov), 2015
The obtained analytical expressions allow us to evaluate the stability of two-axle vehicles at various slowdowns. An analytical expression for calculating the ideal according to condition stability ensuring of a two-axle vehicle at service brake ...
M. Podryhalo, A. Turenko
doaj  

Design Explorations on the Brake Force Distributions of a Motorbike

open access: yesJournal of Applied Engineering Design and Simulation
The braking system is crucial for motorbike safety, as effective braking ensures both deceleration and stability. This study investigates the influence of the deceleration rate and the combined biker and pillion load on the optimal distribution of the braking force of a motorbike.
Mahamad Hisyam Mahamad Basri   +4 more
openaire   +1 more source

A Biomimetic Dual‐Targeting Nano‐APA‐Editor Reprograms the 3'UTR Landscape for Tongue Squamous Cell Carcinoma Therapy

open access: yesAdvanced Science, EarlyView.
This study unveils a pathogenic axis in oral cancer where NUDT21 suppresses a tumor suppressor network, prominently PTEN, via 3'UTR lengthening. To exploit this transcriptomic vulnerability, we developed a biomimetic Nano‐APA‐editor. By delivering CRISPR/Cas9, we reprogrammed the global 3'UTR landscape, restoring multi‐target tumor suppression and ...
Yiran Ao   +5 more
wiley   +1 more source

Analysis of the Braking Performance of the Hydraulic Retarder in Mining Dump Truck based on AMESim

open access: yesJixie chuandong, 2016
The hydrodynamic retarder is one of the important auxiliary braking system in mining dump truck,which has an important influence on the braking force distribution and braking performance of the vehicle.
Deng Lin
doaj  

Composite Braking Control Strategy for Electromechanical-Hydraulic Vehicles

open access: yesCSEE Journal of Power and Energy Systems
Short driving ranges and low braking energy recovery efficiencies are two recognized technical bottlenecks to be overcome in electric vehicles. In this paper, a novel electromechanical-hydraulic coupling system is proposed and integrated as a powertrain ...
Zewen Meng   +6 more
doaj   +1 more source

Development of a Cooperative Braking System for Front-Wheel Drive Electric Vehicles

open access: yesEnergies, 2018
Most electric vehicles adopt cooperative braking systems that can blend friction braking torque with regenerative braking torque to achieve higher energy efficiency while maintaining a certain braking performance and driving safety.
Di Zhao   +4 more
doaj   +1 more source

Beyond Potency: Emerging Determinants and Optimization Strategies Enhancing Therapeutic Efficacy of Adult Stem Cells

open access: yesAdvanced Science, EarlyView.
Adult stem cell therapy requires more than high in vitro potency. This review proposes a systems framework in which cell‐intrinsic programs, instructive microenvironmental cues, and pre‐/post‐delivery engineering are co‐designed under standardized translational rules.
Soo‐Rim Kim   +2 more
wiley   +1 more source

Automation of Surgical Workflow Recognition: Unveiling the Surgical Instrument Kinematics that Underly Robot‐Assisted Prostatectomy Procedures

open access: yesAdvanced Intelligent Discovery, EarlyView.
Automated procedural analysis is recognized as one of the major game changers for robotic surgery. Meaning digital analysis needs to replace the manual assessments that set todays standard. Mechanical robotic‐instrument tracking enables the derivation of quantitative kinematic metrics that support behavior‐based workflow segmentation into distinct ...
Kateryna Pirkovets   +4 more
wiley   +1 more source

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