Results 51 to 60 of about 3,864 (261)

In Situ X‐Ray Tomography and Acoustic Emission Monitoring of Damage Evolution in C/C‐SiC Composites Fabricated by Liquid Silicon Infiltration

Advanced Science, EarlyView.
This study investigates how the internal structure of fiber‐reinforced ceramic composites affects their resistance to damage. By combining 3D X‐ray imaging with acoustic emission monitoring during mechanical testing, it reveals how silicon distribution influences crack formation.
Yang Chen, Renato S. M. Almeida, Stefan Flauder, Guillaume Couégnat, Kamen Tushtev, Jürgen Horvath, Peter Wriggers, Kurosch Rezwan   +7 more
wiley   +1 more source

Engineered Exosomal miR‐146a‐5p Reprograms BMSC Fate and Restores Mitochondrial Homeostasis in Glucocorticoid‐Induced Osteonecrosis of Femoral Head

Advanced Science, EarlyView.
Exosomal miR‐146a‐5p is identified as a pivotal regulator in steroid‐induced osteonecrosis. Its reduction activates NF‐κB signaling, compromises mitophagy, and disrupts mitochondrial bioenergetics, resulting in autophagic disequilibrium. Engineered exosomes delivering miR‐146a‐5p reinstate mitochondrial function, augment oxidative phosphorylation and ...
Zehui Lv, Xuejie Cai, Yiming Xu, Xingdong Yang, Ruoying Wang, Han Wang, Yixin Bian, Jiawei Xu, Jiao Lu, Lulu Liu, Yingjie Wang, Jibin Song, Bin Feng, Xisheng Weng   +13 more
wiley   +1 more source

Enhanced Regenerative Braking Strategies for Electric Vehicles: Dynamic Performance and Potential Analysis

Energies, 2017
A regenerative braking system and hydraulic braking system are used in conjunction in the majority of electric vehicles worldwide. We propose a new regenerative braking distribution strategy that is based on multi-input fuzzy control logic while ...
Boyi Xiao, Huazhong Lu, Hailin Wang, Jiageng Ruan, Nong Zhang   +4 more
doaj   +1 more source

A Biomimetic Dual‐Targeting Nano‐APA‐Editor Reprograms the 3'UTR Landscape for Tongue Squamous Cell Carcinoma Therapy

Advanced Science, EarlyView.
This study unveils a pathogenic axis in oral cancer where NUDT21 suppresses a tumor suppressor network, prominently PTEN, via 3'UTR lengthening. To exploit this transcriptomic vulnerability, we developed a biomimetic Nano‐APA‐editor. By delivering CRISPR/Cas9, we reprogrammed the global 3'UTR landscape, restoring multi‐target tumor suppression and ...
Yiran Ao, Bin Gu, Hui Zhao, Kun Tan, Qin Zhao, Zhengjun Shang   +5 more
wiley   +1 more source

Optimization of Regenerative Braking Control Strategy in Single-Pedal Mode Based on Electro-Mechanical Braking

IEEE Access
To enhance the braking stability of electric vehicles and maximize braking energy recovery, this paper proposes a regenerative braking force distribution strategy based on Electro-Mechanical Braking (EMB) in a single-pedal mode.
Xiaobin Ning, Zhenghao Wang, Yong Lin, Yuming Yin, Jiazheng Wang, Yihao Hong   +5 more
doaj   +1 more source

Research of braking peculiarities of used cars [PDF]

Transport, 2002
This paper briefly describes some analysis of a car braking process - the peculiarities of car wheel-to-road adhesion, the influence of distribution of braking forces on car stability between front and rear axles.
V. Mitunevičius, S. Nagurnas
doaj  

Study on influences of brake force distribution to vehicle motions (Numerical calculation of pitch motion and contact forces, and the comparison with experimental results)

Nihon Kikai Gakkai ronbunshu, 2014
Appropriate relation among the inertia, suspension characteristics and brake force distribution will be required for achieving comfortable motion of vehicle and stable contact forces at braking. At a forethought stage where the design concept is decided,
Ryoichi KURASAKO, Goro OBINATA, Kazufumi TORIYA   +2 more
doaj   +1 more source

PRMT5‐Dependent Stabilization of VPS34 Orchestrates Copper Trafficking to Shield Cancer Cells from Cuproptosis and Radiotherapy

Advanced Science, EarlyView.
Radioresistance arises partly from tumor cells evading cuproptosis via unknown defenses. This study reveals that the PRMT5‐VPS34 axis acts as a radiation‐activated anticuproptotic mechanism: PRMT5 methylates VPS34 at Arg174, recruiting USP10 to remove K48‐linked ubiquitination and prevent degradation.
Wei Chen, Ming‐Ying Xiao, Lan‐Lan Guo, Hao‐Yue Hu, Sui‐Xian Zhang, Bai‐Qiang Dong, Chen‐Fei Wu, Xia‐Hang Huang, Li Li, Run‐Zhe Chen, Yuan‐Yang Huang, Ying Jin, Hai Song, Ying Wang, Qi‐Wen Li, Ming Chen, Xuan Li, Yuan‐Yuan Chen   +17 more
wiley   +1 more source

Long Downhill Braking and Energy Recovery of Pure Electric Commercial Vehicles

World Electric Vehicle Journal
The thermal decay of the brake has a great impact on the long downhill braking stability of pure electric commercial vehicles. Based on the road slope and using the fuzzy control method, the motor regenerative braking force and friction braking force ...
Weisheng Cai, Chengye Liu
doaj   +1 more source

CXCL10/SLC11A1 Axis Exacerbates Septic Liver Injury by Regulating Neutrophil Extracellular Traps Formation to Drive Macrophage Pro‑Inflammatory Polarization

Advanced Science, EarlyView.
In sepsis‐induced liver injury, marked neutrophil infiltration correlates with disease severity. Neutrophil SLC11A1 drives intracellular Fe2+ and ROS via the Fenton reaction, promoting NETs formation. Hepatocyte‐derived CXCL10 recruits neutrophils and activates the JAK/STAT1/SLC11A1 axis, enhancing NETs‐mediated inflammation.
Haiping Lin, Shicong Zheng, Pei Song, Jie Chang, Zewei Chen, Cang Li, Min Yu, Lude Wang, Shian Yu   +8 more
wiley   +1 more source