Results 41 to 50 of about 1,865 (214)

Statistical Analysis of Temperature Effects on Brake Force and Efficiency in Vehicle Braking Systems: A Comprehensive Study [PDF]

E3S Web of Conferences
The vehicle braking system is critical for ensuring road safety, particularly under high-temperature conditions caused by friction during braking. Thermal stress in braking components leads to the degradation of friction materials, reducing braking ...
Shofiah Siti, Syah Ide Navis, Hadi Suprapto, Widiandaru Nanang Okta, Asmin La Ode   +4 more
doaj   +1 more source

Instructor’s Rating of Driver’s Performance during an Anti-Lock Braking Exercise on a Closed-Road Course

Safety, 2021
Rear-end crashes are a common crash scenario, which contribute to many traffic related injuries and fatalities. A performance driving center offers adult car control classes focused on defensive driving skills, which include both classroom and behind-the-
Lauren Mims, Johnell O. Brooks, Timothy M. Jenkins, Casey Jenkins, Joseph Neczek, Donnie Isley, Allison Bormann, Laura Hayes, Daniel Gubitosa   +8 more
doaj   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Analysis of the Braking Performance of the Hydraulic Retarder in Mining Dump Truck based on AMESim

Jixie chuandong, 2016
The hydrodynamic retarder is one of the important auxiliary braking system in mining dump truck,which has an important influence on the braking force distribution and braking performance of the vehicle.
Deng Lin
doaj  

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Plotting the adhesion utilization curves for multi-axle vehicles

Қарағанды университетінің хабаршысы. Физика сериясы, 2021
The paper presents a method for calculating normal reactions of the road bearing surface along the axles of a multi-axle wheeled vehicle, upon which it is possible to construct the adhesion utilization curves for all vehicle axles, considering that both
В.A. Богомолов, В.И. Клименко, Д.Н. Леонтьев, С.В. Поникаровская, А.А. Кашканов, В.Ю. Кучерук   +5 more
doaj   +1 more source

The Comprehensive Live Cell‐Based Cytotoxicity Assay for Monitoring Disease Activity and Guiding Rescue Therapy in Acute Attacks of NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu, Jie Ding, Yupeng Du, Guibao Luo, Jinming Li, Rui Liu, Xiaoyi Xu, Xiao Li, Minshu Li, Wei Jiang, Chunsheng Yang   +10 more
wiley   +1 more source

An Optimal Slip Ratio-Based Revised Regenerative Braking Control Strategy of Range-Extended Electric Vehicle

Energies, 2020
The energy recovered with regenerative braking system can greatly improve energy efficiency of range-extended electric vehicle (R-EEV). Nevertheless, maximizing braking energy recovery while maintaining braking performance remains a challenging issue ...
Hanwu Liu, Yulong Lei, Yao Fu, Xingzhong Li   +3 more
doaj   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonists in Multiple Sclerosis: A Topical Narrative Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The glucagon‐like peptide‐1 (GLP‐1) receptor agonists (RAs) are a relatively new class of drugs that were initially approved by the US Food and Drug Administration to improve glycemic control in patients with type 2 diabetes mellitus and, subsequently, weight reduction in patients with obesity.
Audrey Y. Chang, Farrah J. Mateen
wiley   +1 more source

Artemisinin‐Loaded Core‐Shell Microspheres Modulate Histone Lactylation to Remodel the Microenvironment for Cartilage Protection in Rheumatoid Arthritis

Advanced Healthcare Materials, EarlyView.
ART@PLGA@GH‐A microspheres are developed via microfluidic technology for intra‐articular delivery of artemisinin. The system remodels rheumatoid arthritis microenvironments by regulating metabolic and inflammatory disorders, reducing lactate‐driven histone lactylation and cellular senescence, while restoring cartilage homeostasis and protecting joint ...
Shijie Meng, Jianxin Li, Yuyang Luo, Yisi Liu, Feng Xing, Yingchen Ni, Fengyuan Zhang, Zhicheng Fan, Hua Xu, Weidong Zhang, Youhua Wang   +10 more
wiley   +1 more source